... study involved bradycardia,cerebral infarction, oedema, hypotension and intracranialhaemorrhage in the remifentanil group, raised ICP in the fenta-nyl group, and bradycardia and raised ICP in ... addition of a sedativeagent at a reduced dosage.It has been reported that fentanyl, sufentanil and alfentanil canincrease ICP [21,22], probably because of a vasodilatory response, secondary to systemic ... adverse event involving brady-cardia in a patient treated with remifentanil. This occurred in a 63-year-old male with a history of atrial fibrillation receivingremifentanil in combination with...