Immobilizing topoisomerase I on a surface plasmon resonance biosensor chip to screen for inhibitors pptx
Immobilizing topoisomerase I on a surface plasmon resonance biosensor chip to screen for inhibitors pptx
... DNA-TopI binders for interaction and for primary screening of TopI inhibitors. Conclusions: TopI immobilized on the chip retained its bioactivities of DNA binding and catalysis of intermediates ... Medicine, Taipei Medical University, Taipei, Taiwan, 3Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan, 4Institute of Molecular Biology, Academia Sinica, ... by inhibitors and results in failure of re-ligation. Attempts at new derivative designs for TopI inhibition are enthusiastically being pursued, and TopI inhibitors were developed for a variety...
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Báo cáo Y học: Interaction of bovine coagulation factor X and its glutamic-acid-containing fragments with phospholipid membranes A surface plasmon resonance study pdf
... thuspossible that binding of at least some Gla domain-containing proteins to biological membranes will besensitive to local variations in the Ca2+concentration inthe immediate vicinity of ... Gla-domain has a conformation that is appropriate for membrane binding.Equilibrium binding isothermsThe concentration dependence of factor X binding is shownin Fig. 2. It is apparent that ... assumption.DISCUSSIONCalcium binding to the Gla domain is known to be crucial for the induction of a conformation in the domain thatmediates membrane binding. Early studies employingequilibrium dialysis established...
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Báo cáo khóa học: Binding analyses between Human PPARc–LBD and ligands Surface plasmon resonance biosensor assay correlating with circular dichroic spectroscopy determination and molecular docking ppt
... Rmax, maximum analyte binding capacity;k on , association rate constant; koff: dissociation rate constant; KD, equilibrium dissociation constant. KD¼ koff/k on ; v2statistical value in ... to PPARc, even at millimolar concentrations(Fig. 2C).SPR biosensor experiments require immobilization of a receptor or ligand on a surface and monitoring its binding to a second component in ... polar head such as cis-parinaricacid, linoleic acid, 15-d-PGJ2and palmitic acid (Table 2). Incomparison with other ligands, GI262570 forms severaladditional hydrophobic contacts with PPARc...
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Báo cáo Y học: Characterization of heparin binding by a peptide from amyloid P component using capillary electrophoresis, surface plasmon resonance and isothermal titration calorimetry ppt
... electrophoresis (CE), surface plasmon resonance (SPR), and isothermal titration calorimetry(ITC). By CE, heparin-binding activity was readily apparent for both a regular peptide and a slightly N-terminallymodified ... binding; surface plasmon resonance; capillary electrophoresis; isothermaltitration calorimetry.Amyloid P component (AP) is a heparin-binding serumprotein, which is also found outside the circulation ... greater than a tetrasaccharide sizegave optimal binding. It is interesting to note that practicallyno interaction of sequence scrambled AP-1 peptide to heparin oligosaccharides could be measured...
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Báo cáo hóa học: " Sensitive and molecular size-selective detection of proteins using a chip-based and heteroliganded gold nanoisland by localized surface plasmon resonance spectroscopy" pptx
... promisingalternative for achieving high sensitivity, and selectivityat low concentrations.The optical properties of metallic nanomaterials arisefrom localized surface plasmon resonance (LSPR), whichis ... 124:10596.17. Hiep HM, Yoshikawa H, Saito M, Tamiya E: An interference localized surface plasmon resonance biosensor based on the photonic structureof Au nanoparticles and SiO2/Si multilayers. ACS Nano ... materials that are reasonably stable, and its subse-quent application to simple and low-cost diagnostics.Optimization of heterolihanded gold nanoisland for thehigh sensitivity For the sensitive...
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PLASMONICS NANOFOCUSING BASED ON LONGRANGE SURFACE PLASMON POLARITONS
... the spatial grid does not allow discontinuity of both permittivity and permeability to occur simultaneously. 3.6 Terminating The Simulation Domain A basic consideration with implementation of ... Figure 2.2 Schematic for the localization of photons by a metal-coated axicon prism [10] 33 Figure 2.3 Intensity distributions on a gold-coated axicon prism for radially polarized incident light ... transfer via evanescent coupling. In conclusion, we see that surface plasmon polaritons can be excited by TM polarized wave on the surface between a dielectric and a conductor. In a metal slab waveguide,...
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Báo cáo sinh học: " Rapid label-free identification of mixed bacterial infections by surface plasmon resonance" pdf
... biochemical identification system. API Staph(BioMeri eux, USA) was used for identification of S aur-eus and API 20 A (BioMerieux, USA) for identificationof P. aeruginosa, C. tetani and C. perfringens ... accurately identify the mixed aerobic-anaerobic infection, providing a reliable alternative to bacterial culture for rapid bacteria detection.Keywords: bacterial infection biosensor, mixed infection, ... more than 100 times (Figure 4B).DiscussionDiscriminating a mixed bacterial infection by traditiona lculture- and b iochemical character-based methods is a challenge in clinical practice because...
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báo cáo hóa học:" Rapid label-free identification of mixed bacterial infections by surface plasmon resonance" pptx
... contributionsJW and YL have made substantial contributions to conception and design,data acquisition, analysis and data interpretation and are involved in draft ingand revising the manuscript. WF has made ... substantial contributions to conception and design.BZ, MC, TJ, PL, JH, KZ and WG have made substantial contributions to dataacquisition, analysis and data interpretation. Moreover, each author ... obtained by bacterial revival, isolation and cul-ture were identified using the API biochemical identifi-cation system and used as the target bacterial strains(data not shown).Identification...
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Báo cáo hóa học: " Properties of nanocones formed on a surface of semiconductors by laser radiation: quantum confinement effect of electrons, phonons, and excitons" pptx
... conversion of light into heat and lateral deforma-tion of the crystalline lattice of a semiconductor takesplace due to inhomogeneous absorption of light, leading to formation of periodical structure ... formation of mechanically com-pressed layer at the irradiated surface due to increase of concentration of the interstitial atoms ofSi at the surface in temperature gradient field, whichis characteristic ... Si like a thin film. As a result, LRA stage gradually tran-sits to SLA stage.The second stage, SLA, is characterized by formation ofnanocones on the irradiated surface of a semiconductorby...
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Báo cáo hóa học: " Plasmonic propagations distances for interferometric surface plasmon resonance biosensing" ppt
... NANO EXPRESS Open AccessPlasmonic propagations distances for interferometric surface plasmon resonance biosensingDominic Lepage, Dominic Carrier, Alvaro Jiménez, Jacques Beauvais and Jan ... nanofabrication team for their helpful participation.Authors’ contributionsDL carried out the main conception and design of the SPR architectures,participated in the analysis and interpretation of data, ... a semi-in finite flat interface of Auand air, with a regular array of finite gratings, evenlyseparated and illuminated as in Figure 1. The 20-nmhigh sinusoidal gratings have a periodicity of...
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Từ khóa: 3 10 tensors on a surface or hypersurfacecondensation reaction of cd and te2 vapors on a surfacelabel free detection with surface plasmon resonance imagingmonetary amounts received that are not earmarked for a specific purpose shall be taken to income for the reporting period in which they are recognisedôn thi hoc sinh giỏi địa 12can i play a powerpoint presentation on my smart tvcan i play a powerpoint presentation on my tvcan i play a powerpoint presentation on my tv via usbcan i play a powerpoint on my tvcan i run a powerpoint presentation on my tvcan i run a powerpoint presentation on a smart tvcan i play a powerpoint on apple tvcan i play a powerpoint presentation on a tvhow can i play a powerpoint on a tvcan i use my iphone as an ipod on a planeNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinBT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘI