Báo cáo y học: "Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways" ppsx
... Watanabe M, Ohsugi T, Shoda M, Ishida T, Aizawa S, Maruyama-Nagai
M, Utsunomiya A, Koga S, Yamada Y, Kamihira S, Okayama A, Kikuchi
H, Uozumi K, Yamaguchi K, Higashihara M, Umezawa K, Watanabe ... Research and Therapy
Open Access
Research
Two specific drugs, BMS-345541 and purvalanol A induce apoptosis
of HTLV-1 infected cells through inhibition of the NF...
... and differential, normal renal function
and normal hepatic function. She was admitted on day 6
of the cycle with febrile neutropenia, grade 2 mucositis
and grade 2 arthralgia and myalgia. Apart ... her
oesophagogastroduodenoscopy (OGD) and flexible sig-
moidoscopy revealed widespread ulceration in the eso-
phagus and gastric antrum that was biopsied. Meanwhile,
a galacto...
...
ACC: American College of Cardiology; AHA:
American Heart Association; CABG: coronary artery
binding graft; CK: creatine kinase; MACE: major ad-
verse cardiac events; MI: myocardial infarction; ...
results of these initial trials indicate that the ZES is
safe and reduces the rates of clinical and angiographic
restenosis in patients with symptomatic coronary ar-
tery disease...
... important given
the frequency of femoral and acetabular defects asso-
ciated with THA infections
[7-9].
The aim of a two-stage revision is to eradicate
any residual bacteria after removal of the ... use of PROSTALAC
for the 2-stage revision of infected THA. The cement
of the femoral head
articulated with the bone of the
acetabular bed causing bone er...
... (asynchr.)
was also analyzed. The percentage of cells in the G0/G1, S, and G2/M
phases of the cell cycle at each time point was determined by FACS
analysis and is shown at the bottom.
Fig. 4. Translation of ... 5¢-GGGAATTCTCAGATAGAGTCTTCTCTGG
GAGC-3¢
SG50: 5¢-GGGGACCAGGGTGACCGCGG-3¢
SG92: 5¢-GCGCGGGAGATCTAACGGACGG-3¢
SG108: 5¢-CCTCTAGACGCGCCGTCCGGTGCTGAC
TCAT-3¢
SG109:...
... insertion of a selenocysteine in mammal
GPXs. The selenocysteine residue is important for the
catalytic activity of GPX as replacement of selenocysteine by
cysteine greatly reduces the activity of the ... variations
in the tissue and the subcellular concentrations of substrates
and reducing substrates, dual catalytic activities for a given
enzyme might constitute...
... several stabilizing
van der Waals’ contacts between the O4¢ atoms of the DNA
sugars and distamycin atoms are observed.
Rings A and B make an angle of 8.6 °,ringsBandC
21.1 °, and ring C makes an angle ... chemical calculations in
further analysis of crystallographic results, a combination
Table 3. Close contacts of atoms in the minor groove of d(GGCCAATTGG) or d(CGCA...
... Example of calculation of the index of the quantity of allergen -specific Th cells and the number of precursor cells of
acquired allergen -specific cells (needed to calculate the absolute count of ... allergen -specific Th
or B cells was based on the ability of the cells to prolif-
erate. We assumed that all allergen -specific cells prolif-
erated...
... half of the RP
patients the cartilage of the tracheolaryngeal tract is
affected. This is a potentially fatal symptom caused by a
collapse of tracheal rings and bronchi and/ or by inflamma-
tory ... RP and also indi-
cates that shared pathogenic pathways might be used in
RP and RA. As large variations in the severity and targets
of the inflammatory attack appear...