Báo cáo y học: "Pre-clinical development as microbicide of z

Báo cáo y học: "Pre-clinical development as microbicide of zinc tetra-ascorbo-camphorate, a novel terpenoid derivative: Potent in vitro inhibitory activity against both R5- and X4-tropic HIV-1 strains without significant in vivo mucosal toxicity" docx

... purposes) AIDS Research and Therapy Open Access Research Pre-clinical development as microbicide of zinc tetra-ascorbo-camphorate, a novel terpenoid derivative: Potent in vitro inhibitory activity against ... leucocytes infiltration, vascular congestion and oedeme, were calculated as the mean of the scores estimated at the cervicovagina, midvagina and...

Ngày tải lên : 10/08/2014, 05:21

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Báo cáo y học: " Prolactinoma presenting as chronic anaemia with osteoporosis: a case report" pdf

... trauma, during the preceding year. His serum prolactin was massively increased and a magnetic resonance imaging (MRI) scan of the head demonstrated a pituitary mass consistent with a prolactinoma. ... prolactinoma was present during the initial presentation and was the cause of his anaemia. Conclusion: This case highlights the importance of fully evaluating and investigating...

Ngày tải lên : 11/08/2014, 14:21

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Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"

... Okuno T, Tamura T, Yamamori M, Chayahara N, Yamada T, Miki I, Okamura N, Kadowaki Y, Shirasaka D, Aoyama N, Nakamura T, Okumura K, Azuma T, Kasuga M, Sakaeda T. Favorable genetic polymorphisms ... Ehninger G, Stoehlmacher J. Phar- macogenetic analyses of a phase III trial in metastatic gastroesoph- ageal adenocarcinoma with fluorouracil and leucovorin plus either oxaliplatin or c...

Ngày tải lên : 25/10/2012, 10:51

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Tài liệu Báo cáo Y học: Ornithine decarboxylase-antizyme is rapidly degraded through a mechanism that requires functional ubiquitin-dependent proteolytic activity pot

... S., Matsufuji, T., Miyazaki, Y. , Murakami, Y. , Atkins, J.F., Gesteland, R.F. & Hayashi, S. (1995) Autoregulatory frame- shifting in decoding mammalian ornithine decarboxylase antizyme. ... Murakami, Y. , Matsufuji, S., Kameji, T., Hayashi, S., Igarashi, K., Tamura, T., Tanaka, K. & Ichihara, A. (1992) Ornithine decarboxylase is degraded by the 26S proteasome without ubiqui...

Ngày tải lên : 22/02/2014, 04:20

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Báo cáo Y học: Monitoring the structural consequences of Phe12 ﬁ D-Phe and Leu15 ﬁ Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf

... information towards the design and synthesis of new molecules with higher binding afﬁnity and enhanced stability against biological degradation and possibly biological activity. The impact of Aib introduction ... studies and biological activity evaluation of new CRH analogues are in progress in our laboratory. Fig. 4. (A) Surface electrostatic potentials of CRH analog...

Ngày tải lên : 17/03/2014, 10:20

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Báo cáo Y học: Puri®cation and characterization of the human adenosine A2a receptor functionally expressed in Escherichia coli doc

... the main contamination, seen in lane 1, run s only m arginally above the hA2aR fusion pro tein and is the main band in lane 2. In this pu ri®cation, 7% of speci®c ligand binding sites loaded ... fusion protein was characterized by ligan d b inding analyses to judge its identity and integrity. Binding of the antagonist [ 3 H]ZM241385 was speci®c and saturable for both membran...

Ngày tải lên : 24/03/2014, 00:21

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Báo cáo y học: "The emerging modern face of mood disorders: a didactic editorial with a detailed presentation of data and definitions" potx

... malignancies (especially in the pancreas) and disseminated carcinoma- tosis. Also, there are a number of abnormal endocrine conditions including hypothyroidism and hyperthyroid- ism, hyperparathyroidism, hypopituitarism, ... brain magnetic resonance imaging (MRI) scans, and in late onset cases indices assessing malig- nancy. Suicide Today we know that suicide is a complex and...

Ngày tải lên : 08/08/2014, 23:21

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Báo cáo y học: "Relationship between radiographic grading of osteoarthritis and the biochemical markers for arthritis in knee osteoarthritis" doc

... between radiographic grading of osteoarthritis and the biochemical markers for arthritis in knee osteoarthritis Masaaki Takahashi, Kenichi Naito, Masashi Abe, Tomokazu Sawada and Akira Nagano Department ... pyridinoline were corrected by urinary creatinine. The intra-assay and interassay coefficients of variance were 6.4% and 5.9%, respectively. Serum YKL-40 Serum YKL-40 was mea...

Ngày tải lên : 09/08/2014, 01:23

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Báo cáo y học: "First-dose analgesic effect of the cyclo-oxygenase-2 selective inhibitor lumiracoxib in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled comparison with celecoxib [NCT00267215]" doc

... treatment and centre as main effects, whereas baseline actual pain was used as a covariate. Data from small centres were pooled using a predefined algorithm. APID, AVPID and WPID were analyzed at ... day of treatment. Secondary variables included evaluation of treatment over 7 days during the multiple-dose pain assessment phase. Patients rated actual pain intensity, average pa...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: "Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling" ppsx

... design, analysis and interpretation of data, manuscript preparation, and statistical analysis. SKT participated in acquisition of data, analysis and interpretation of data, and manuscript preparation. ... interpretation of data, manuscript preparation, and statistical analysis. J-PP participated in study design, analysis and interpretation of data, and manuscri...

Ngày tải lên : 09/08/2014, 10:23

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