... early inflammatoryreactions as well, in this particular study, an acute arthritisscore of 0.5 was given if at least two interphalangeal, meta-carpo-phalangeal, or metatarso-phalangeal joints ... separated about 70 years ago and the correspondingmicroarray results indicate that, indeed, a single or a limitednumber of mutations may dramatically affect the clinical phe-notype of arthritis ... systematicallymated and an inbred colony was established in 1920 [71].The original BALB/c colony was separated in 1935. One of these colonies was maintained by G. Snell at The JacksonLaboratory...