Báo cáo y học: " HIV-1 reverse transcriptase mutations that

Báo cáo y học: " HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors" docx

... N265 may not play a key role in binding to RT8 . It is also interesting that N255D mutant displays a 10-fold hypersensitivity to RT8 . We surmise that N255 residue may be involved in binding to RT8 ... the aptamers (RT2 6, RT4 and RT6 ), the pattern of resistance was very similar to that seen with RT1 t49 in that the reduction in susceptibility was smal...

Ngày tải lên : 10/08/2014, 05:20

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Báo cáo y học: " Phase IIb randomized trial of adjunct immunotherapy in patients with first-diagnosed tuberculosis, relapsed and multi-drug-resistant (MDR) TB" doc

... used in this arm are abbreviated as follows: Isoniazid (H), Rifampicin (R), Pyrazinamide (Z), Ethambutol (E), Streptomycin (S), Ofloxacin (O), Amikacin (A), Capreomycin (C), Para-aminosalicylic ... were earlier indications that V5 exhibits the anti-inflammatory activity [4-8]. These observations are supported by this study. Contrary to the outcome in placebo group the markers of infla...

Ngày tải lên : 11/08/2014, 08:21

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Tài liệu Báo cáo Y học: BIGH3 (TGFBI) Arg124 mutations inﬂuence the amyloid conversion of related peptides in vitro Implications in the BIGH3-linked corneal dystrophies pptx

... local factors may also explain the corneal involve- ment in other forms of amyloidosis [26]. In summary, autosomal dominant corneal diseases linked to mutations in the BIGH3 gene are a prominent ... transformation. Blocking the Cys residues decreased amyloid formation by approximately 50%, demonstrating that Cys–Cys bond formation does facilitate amyloid precipitation, but i...

Ngày tải lên : 21/02/2014, 01:21

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Báo cáo Y học: Introducing Wilson disease mutations into the zinc-transporting P-type ATPase ofEscherichia coli The mutation P634L in theÔhingeÕ motif (GDGXNDXP) perturbs the formation of the E2P state pdf

... the metal binding and phosphorylation sites. It should be noted that binding of the metal ion initiates the catalytic cycle [6]. This binding event in the TM part should trigger changes in the P ... involved in binding of Mg 2+ [34–37]. Moreover, the E 1 to E 2 transition may be linked to changes in Mg 2+ ligation so that in the E 1 state Mg 2+ is ligated by residues in th...

Ngày tải lên : 17/03/2014, 17:20

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Báo cáo y học: "LV reverse remodeling imparted by aortic valve replacement for severe aortic stenosis; is it durable? A cardiovascular MRI study sponsored by the American Heart Association" pot

... myocyte hypertrophy is not the only pathology that must be accounted for and con- sequently regress post-AVR. Were both sarcomere hypertrophy and collagen expression to be finely gov- erned by ... increasing due to aortic and peripheral changes in compliance and arterial inelasticity due to aging. The surgically induced relief of a fterload may be counterbalanced by the resultant...

Ngày tải lên : 10/08/2014, 09:21

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Báo cáo y học: "Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections"

... defined previously [34]. Thereby, LRTI was defined by the presence of at least one respiratory symp- tom (cough, sputum production, dyspnea, tachypnea, pleuritic pain) plus at least one finding ... Obrosky DS, Peyrani P, Johnson B, Hooy M, Grayson ML: SMART-COP: a tool for predicting the need for intensive respiratory or vasopressor support in community-acquired pneumonia. Clin Infect ......

Ngày tải lên : 25/10/2012, 10:02

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Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"

... Academic centers are increasingly recognizing engagement in quality improvement as a distinct career pathway. Involving such physicians in medical emergency teams will likely facilitate the dual ... The increased effort required for the study consisted of only a 5-minute debriefing to fill out the standardized MET form on each patient and a weekly 1-hour Commentary The evolving story of...

Ngày tải lên : 25/10/2012, 10:06

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Báo cáo y học: "Trace Elements, Heavy Metals and Vitamin Levels in Patients with Coronary Artery Diseas"

... sig- nificantly lower in patients with CAD compared to the control group. Other investigators have also re- ported decreased retinol levels in patients with CAD (31,32). In other studies, Levels of retinol ... strongest supporting evidence that Fe is a risk factor for CAD stems from a cohort study of eastern Finnish men, in which high levels of serum ferritin and dieta...

Ngày tải lên : 25/10/2012, 10:51

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Báo cáo y học: "Aplasia and Agenesis of the Frontal Sinus in Turkish Individuals: A Retrospective Study Using Dental Volumetric Tomograph"

... exact drainage system of the frontal sinus depends on its embryologic development [2,13]. The drainage usually occurs directly into the frontal recess [14] or into the frontal recess by way of ... ex- tending above a line tangential to the supraorbital margin (horizontal line). Frontal sinus aplasia is also defined by an oval-shaped sinus with the lateral margin medial to a vertical...

Ngày tải lên : 25/10/2012, 11:04

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Báo cáo y học: "Optimization of 5-fluorouracil solid-lipid nanoparticles: a preliminary study to treat colon cancer"

... formulation parameters; including type of Dynasan, soyalicithin:Dynasan ratio, drug:total lipid ratio, and polyvinyl al- cohol (PVA) concentration were studied with respect to particle size and drug ... 30. Yassin AE, Alsarra IA, Alanazi FK, et al. New targeted-colon delivery system: in vitro and in vivo evaluation using x-ray imaging. J Drug Target. 2010; 18: 59-66. 31. Alanazi...

Ngày tải lên : 25/10/2012, 11:22

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