Báo cáo y học: "What does the marriage of Open Access with online publication bring" docx

Báo cáo y học: "What is the clinical and ethical importance of incidental abnormalities found by knee MRI" docx

... facilitate the institution of an appropriate system.Although the frequency of these lesions is low, they may have clinical significance and may be the first sign of life-threateningdisease. Researchers ... lesions, incidental to the pur-pose of the imaging, are not missed. There may be a number of ways of providing this function apart from review by a mus-culoskeletal radiologist or other suitably trained ... requiring therapy, and those with a history of significant knee trauma, this is unlikely:these subjects would not have otherwise undergone knee imaging. Subjects with knee OA had already undergone...

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Báo cáo y học: "Cytokines in the colon of a patient with Behçet’s disease" ppt

... of Arthritis Research & Therapy, in whichthey describe cytokine patterns of inflamed joints frompatients with Behỗets disease (BD). The authors show thatneutrophils and T lymphocytes are ... colon by analyzingmRNA expression levels of cytokine genes as previouslydescribed [2]. Because of the extensive prior treatment, the patient served as an internal control. Intestinal inflammationwas ... IL-4, IL-10, andIL-17 were observed. We would like to add to theseobservations our data showing a similar cytokine profile in the colon of a patient with BD. A 37-year-old BD patient with severe...

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Báo cáo y học: "What does the marriage of Open Access with online publication bring" docx

... and the disease caused by it, AIDS. Many of themare now accessible online. However, we are launching the first Open Access journal in the AIDS arena – AIDSResearch and Therapy. The purpose of ... any other barriers to access. In an Open Access journal, the communication has to be bi-direc-tional for the journal's success and improving the quality of the journal. Consequently, the ... together with the Editor/reviewer han-dling the manuscript will be required to declare any com-peting interests. AIDS Research and Therapy will considerfollowing types of articles: Research, Hypotheses,...

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Báo cáo y học: "What is the role of surfactant and inhaled nitric oxide in lung transplantation" pps

... laboratory investigations [8]. Therefore, many lung transplant programmes use iNO routinely during earlyreperfusion of the lung. Bearing in mind that the concept of ischaemia/reperfusion injury in ... role of surfactant in management of initially impaired graft functionafter lung transplantation, and do these findings apply toother forms of lung injury?Ischaemia/reperfusion injury leading ... recovery of the graft. The combination of iNO and surfactant proved to be successful in experimental severe reperfusion injury [15], strengthening the hypothesis that this combination prevents intrapulmonaryshunt...

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Báo cáo y học: "What are the challenges of translating positive trial results in severe sepsis into clinical practice" pptx

... criteria for sepsis in clinical practice or therapeutic trials. The panel went on to discuss what elements should beincluded in the definition of sepsis. Perhaps unsurprisingly,they essentially recreated ... study of rhAPC in severe sepsis, Bakker and colleagues actively considerwhether each patient fulfils the criteria for entry into the study; in short, there is more of a reason to make an earlydiagnosis ... diminish the potential impact of adopting novel therapies/strategies in the treatment of thiscommon and serious syndrome.Conclusion The confusing terminology and woolly definitionssurrounding...

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Báo cáo y học: "What is the best site for central venous catheter insertion in critically ill patients" doc

... at increased risk for pulmonary complications(severe emphysema, acute respiratory distress syndrome)were not included in the analysis – a fact that may explainthis surprising finding. In a ... catheters) [1], malposition was significantlyCommentaryWhat is the best site for central venous catheter insertion in critically ill patients?Jean-Franỗois TimsitRộanimation médicale et infectieuse, ... only 17 wereincluded in the meta-analysis. The meta-analysis populationincluded ICU and non-ICU patients, and no distinction wasmade between catheters inserted for dialysis, pulmonaryartery...

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Báo cáo y học: "What does the structure-function relationship of the HIV-1 Tat protein teach us about developing an AIDS vaccine?" ppsx

... purposes)RetrovirologyOpen AccessReviewWhat does the structure-function relationship of the HIV-1 Tat protein teach us about developing an AIDS vaccine?Grant R Campbell1 and Erwann P Loret*2Address: ... inducingconformational changes [43]. Theses mutations between the vaccine and the virus used for the challenge mightexplain the lack of efficacy of the Tat vectored vaccine in the second study [105]. The second ... Study Group: Sequence conservation and anti-body cross-recognition of clade B human immunodeficiencyvirus (HIV) type 1 Tat protein in HIV-1- infected Italians,Ugandans, and South Africans....

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Báo cáo y học: "Where does the lactate come from? A rare cause of reversible inhibition of mitochondrial respiration" pdf

... the lactate/ pyruvate ratio [8].All in all, anaerobic energy metabolism is characterized by hyperlactatemia associated with an elevated lactate/ pyruvate ratio, greater glucose utilization and ... phosphorylation [7], thereby inhibiting ATP synthesis and reoxidation of NADH.  is leads to a decrease in the ATP/ADP ratio and an increase in the NADH/NAD ratio. A decrease in the ATP/ADP ratio ... should theoretically be accompanied by hypoxic hyperlac-tatemia. Cardiogenic shock, as demonstrated previously [5], is associated with hyperlactatemia with a very high lactate/ pyruvate ratio....

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