Báo cáo y học: "Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level" doc
Báo cáo y học: "Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level" doc
... Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level. Genome Biology 2010 11:R118.Submit your ... 11:R118http://genomebiology.com/2010/11/11/R118Page 13 of 18RESEARC H Open AccessPopulation sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity ... -aGenotype called as reference homozygote by sequencing and heterozygote by MassARRAY or heterozygote by sequencing and alternative homozygote byMassARRAY.bGenotype called as heterozygote by sequencing...
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Báo cáo Y học: Co-existence of two regulatory NADP-glyceraldehyde 3-P dehydrogenase complexes in higher plant chloroplasts ppt
... Sauermann11Plant Physiology, University of Osnabrueck, Germany;2Planton GmbH, Kiel, Germany;3Plant Physiology, University of Kaiserslautern, Kaiserslautern, GermanyLight/dark modulation of the higher ... changes of regulatory cysteines. Here wedemonstrate that plants possess two different complexescontaining the inactive forms (a) of NADP-GAPDH and PRK and (b) of only NADP-GAPDH, respectively, indarkened ... redox-modification at specific cysteine residues mediated by theferredoxin/thioredoxin system [1]. The activity of each of these enzymes is adjusted by fine-tuning, the rates of reduction and/ or of oxidation being...
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Báo cáo Y học: Stimulated biosynthesis of flavins in Photobacterium phosphoreum IFO 13896 and the presence of complete rib operons in two species of luminous bacteria Sabu Kasai and Takumi Sumimoto pot
... Francesco, R.D. (1991) Structure, synthesis, and physical properties of covalently bound flavins and 6- and 8-hydroxyflavins. In Chemistry and Biochemistry of Flavoenzymes(M€uuller, F., ed.), Vol. ... ismonocistronic and not a member of the rib operon [29]. Thisposes the question of whether rib genes are organized inan operon and the genes for 3,4-dihydroxy-2-butanone4-phosphate synthase and GTP cyclohydrolase ... Four enzymes participate in thesynthesis of riboflavin from GTP and ribulose 5-phos-phate: pyrimidine deaminase/pyrimidine reductase,riboflavin synthase, GTP cyclohydrolase II/3,4-dihydr-oxy-2-butanone...
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Báo cáo y học: "Direct sequencing of the human microbiome readily reveals community differences" pps
... of energy in adipocytes [19]. e obesity -associated microbiomes of humans (and mice) are enriched in functional genes for certain types of carbohydrate metabolism, and this is directly attributable ... 5Department of Computer Science, 9Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309, USA. 2Department of Microbiology and Immunology, Stanford University, Stanford, ... communities was primarily explained by body habitat, secondarily by host individual (within habitats), and nally by time (within habitats and individuals). Specically, variation in species...
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Báo cáo y học: " Reduced levels of two modifiers of epigenetic gene silencing" ppsx
... recently identified as playing a centralrole in lipid metabolism and metabolic syndrome [20].Ingenuity Pathway Analysis of dysregulated genes revealed that the two top canonical pathways were ... period of 20 years to ana-lyze the significance of di fferent components of randomvariability in quantitative traits. Reduction of geneticvariability, by using inbred strains, and reduction of environmental ... variability, by standardized husbandry,did not significantly reduce the range of random pheno-typic variability. Simil arly, moving the animal s into thewild to increase environmental variability...
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Báo cáo y học: "Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic nois" pdf
... identified as playing a centralrole in lipid metabolism and metabolic syndrome [20].Ingenuity Pathway Analysis of dysregulated genes revealed that the two top canonical pathways were ‘LPS/IL-1 ... period of 20 years to ana-lyze the significance of di fferent components of randomvariability in quantitative traits. Reduction of geneticvariability, by using inbred strains, and reduction of environmental ... variability, by standardized husbandry,did not significantly reduce the range of random pheno-typic variability. Simil arly, moving the animal s into thewild to increase environmental variability...
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Báo cáo y học: "Systematic mapping of two component response regulators to gene targets in a model sulfate reducing bacterium" ppt
... about the two component regulatory network in sulfate reducing bacteria. Here we provide a fairly comprehensive map of genes that are transcriptionally regulated by the majority of the two component ... cloned in by the Gibson method [50] downstream of the Ptet and upstream of rfp such that they replace the native polymerase and gyrase genes, amino acid transport genes, glutamate synthase, phosphodiesterase ... less biofilm than the wild-type, and the wild type biofilm also contains less carbohydrate and more protein filaments [34]. It is possible that that the two genes are negatively correlated with...
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Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"
... Department of Orthopedics, Affiliated Hospital of Hebei University, Baoding 071000, China. 3. Laboratory of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Academy of Military ... refreshed, and then the medium changed every other day. Cell passaging was per-formed when cell confluence reached 85%. The purity and immunophenotype of MSCs and their potentials of osteogenesis and ... significantly im-proved. However, nowadays, a lot of younger adults develop ischemic femoral head necrosis, and lifetime of prosthesis, risk of surgery and high cost for surgery limit its...
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Báo cáo y học: " Mutation Analysis of hCDC4 in AML Cells Identifies a New Intronic Polymorphis"
... ABI PRISM Big Dye Terminator system (Applied Biosystems, Germany). Sequences were analyzed using the Chromas software (Technely-sium Pty Ltd, Tewantin, Australia) and GeneDoc software (http://www.psc.edu/biomed/genedoc). ... individuals. Interestingly, this SNP had not yet been registered in any SNP databases despite of its high frequency of 20% in samples of patients with AML and 13,7% in healthy individuals. After ... analysis of the hCDC4 gene in 35 samples of patients with Acute Myeloid Leukemia (AML) to elucidate a possible role of hCDC4 mutations in this disease. By direct DNA sequencing and digestion with...
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Báo cáo y học: "The Syndrome of Frontonasal Dysplasia, Callosal Agenesis, Basal Encephalocele, and Eye Anomalies – Phenotypic and Aetiologica"
... frontonasal dysplasia (MIM 136760 and 305645), acrofrontofacionasal dysostosis 1 (MIM 201180), acrofrontofacionasal dysostosis 2 (MIM 201181), frontofacionasal dysplasia (MIM 229400), oculoauriculofrontonasal ... Richieri-Costa A. New Syndrome of Growth and Mental Retardation, Structural Anomalies of the Central Nervous System and First Branchial Arch, Anophthalmia, Heminasal A/hypoplasia, and Atypical Clefting: ... different pattern of cerebral and facial manifestations ranging from normality to typical HPE phenotype. Penetrance is relatively low. Patient 1 of the present study was previously reported as...
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