Báo cáo y học: "Systematic detection of putative tumor suppressor genes through the combined use of exome and transcriptome sequencin" ppt

Báo cáo y học: "Systematic detection of putative tumor suppressor genes through the combined use of exome and transcriptome sequencin" ppt

Báo cáo y học: "Systematic detection of putative tumor suppressor genes through the combined use of exome and transcriptome sequencin" ppt

... to common tumor suppressor genes shared by many cancer types like RB1 and TP53, many tumor suppressor genes are specific to a particular tumor type and/ o r cell type that originate the tumor. Deficiency ... 11:R114 http://genomebiology.com/2010/11/11/R114 Page 4 of 14 RESEARC H Open Access Systematic detection of putative tumor suppressor genes through th...
Ngày tải lên : 09/08/2014, 22:23
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Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx

Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx

... of the drug is hydrogen-bonded to the two O2 atoms of the thymine bases of the central AT steps. Nitrogen atoms N3(D) and N7(D) bridge N3(adenine) and O2(thymine) atoms of opposite strands. Furthermore, ... amino-group pyramidalization. The contacts of the atoms O1(D) and N1(D) at the other side of the drug are more complicated. The interaction energy with...
Ngày tải lên : 24/03/2014, 04:21
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Báo cáo y học: "Hereditary angioedema: beyond international consensus - circa December 2010 - The Canadian Society of Allergy and Clinical Immunology Dr. David McCourtie Lecture" pps

Báo cáo y học: "Hereditary angioedema: beyond international consensus - circa December 2010 - The Canadian Society of Allergy and Clinical Immunology Dr. David McCourtie Lecture" pps

... teaching in the field of Allergy and Clinical Immunology and was well respected as a physician, teacher and colleague. The 2010 Canadian Society of Allergy and Clinical Immunology Dr. David McCourtie ... trials and other studies published on either prophylaxis or therapy of hereditary angio edema and some of these produ cts have changed licensure sta- tus in various co...
Ngày tải lên : 08/08/2014, 21:20
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Báo cáo y học: "4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase" doc

Báo cáo y học: "4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase" doc

... articular chondro- cytes and as the main precursor for the synthesis of ECM gly- cosaminoglycans in cartilage [35,36]. The inhibition of proteoglycan synthesis in OA chondrocytes by HNE (data not shown) ... activity is primarily impor- tant for the observed event. On the other hand, the inhibition of mNADP + -ICDH, an important regulator of the citric acid cycle, by HN...
Ngày tải lên : 09/08/2014, 13:21
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Báo cáo y học: "Introducing Arthritis Research & Therapy’s 10th anniversary issue, ‘The Scientific Basis of Rheumatology: A Decade of Progress’" pdf

Báo cáo y học: "Introducing Arthritis Research & Therapy’s 10th anniversary issue, ‘The Scientific Basis of Rheumatology: A Decade of Progress’" pdf

... gives the reader the advantages of a traditional review text. Overview of part one of The Scientific Basis of Rheumatology: A Decade of Progress Biology and methodology The contribution of Foxwell ... arthritis. Chen and Tuan [2] discuss the potential involvement of MSCs in the pathophysiology of degenerative joint disease and explore the prospects of MSC...
Ngày tải lên : 09/08/2014, 13:22
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Báo cáo y học: " Adjuncts or adversaries to shared decision-making? Applying the Integrative Model of behavior to the role and design of decision support interventions in healthcare interactions" pps

Báo cáo y học: " Adjuncts or adversaries to shared decision-making? Applying the Integrative Model of behavior to the role and design of decision support interventions in healthcare interactions" pps

... contexts over the past 30 years. [21]. These include the Theory of Reasoned Action, the Theory of Planned Behavior, the Health Belief Model and Social Cognitive Theory. [31-34]. Implicit in the combination ... asking questions? Finally, self-efficacy reflects whether a person perceives that they have the necessary skills and abilities to perform the behavior if they real...
Ngày tải lên : 11/08/2014, 05:21
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Báo cáo y học: "CTLA-4 blockade during dendritic cell based booster vaccination influences dendritic cell survival and CTL expansion" ppt

Báo cáo y học: "CTLA-4 blockade during dendritic cell based booster vaccination influences dendritic cell survival and CTL expansion" ppt

... conceived the study, carried out the in vivo experi- ments and flowcytometry, performed the statistical analy- sis and drafted the manuscript. FR participated in the design and coordination of the ... Offringa and has been described previously [14]. The 9H10 antibody was administered as 100 µg/mouse i.p. on the first day together with DC vaccination and 50 µg/mouse...
Ngày tải lên : 11/08/2014, 10:23
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Báo cáo y học: "Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis" pdf

Báo cáo y học: "Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis" pdf

... study is under way. Introduction The prevalence of systemic lupus erythematosus (SLE) varies with age, gender, and ethnicity, and the highest rates occur in young adult women, particularly of ... 2 g daily. The duration of follow-up of patients on MMF was generally between 6 and 36 months, and average follow-ups were gen- erally of 1 year or longer. None of the stu...
Ngày tải lên : 09/08/2014, 08:23
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Báo cáo y học: "Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action" pot

Báo cáo y học: "Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action" pot

... underestimate because our cur- rent analysis is limited by the quality and quantity of the therapeutic data available. Our representations of chemi- cal structure and drug therapeutic use rely on public databases, ... struc- tural similarity (295 and 37 pairs in the heterozygous and homozygous datasets, respectively). Of these pairs, 74% and 90% in the heterozygous...
Ngày tải lên : 09/08/2014, 20:21
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Báo cáo y học: "Phylogenetic detection of numerous gene duplications shared by animals, fungi and plants" ppsx

Báo cáo y học: "Phylogenetic detection of numerous gene duplications shared by animals, fungi and plants" ppsx

... suggested by the ‘ crown-stem’ model [18-20]. Even if the position of the root of the eukaryotic tree is between Excavata and the other supergroups, the split of the lineage with plants and the lineage ... leading to the conclusion that early eukaryotes had significantl y more gene duplicatio n Figure 1 Alternative views of the eukaryotic phylogeny and the...
Ngày tải lên : 09/08/2014, 20:21
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