báo cáo khoa học: "Reaction to halothane anaesthesia among heterozygotes at the halothane locus in British Landrace pigs" doc

... within the first three minutes of test, the test duration was reduced from 5 min in generation 1 to 4 min in generation 2 and 3 minutes in the remaining generations.1. ... at the halothane locus reacting to halothane anaesthesia wasinvestigated using five generations of British Landrace pigs selected for positive or negativereaction to halothane. ... generation 1. As the gene was stillsegregating in the SR line at generation 5, data from the selection lines and inter-linecrosses were pooled within generation, in order...

Báo cáo khoa học: " Exposure to genistein does not adversely affect the reproductive system in adult male mice adapted to a soy-based commercial diet" potx

... important factor to maintainfertilization. Genistein inhibits the induction of acrosomalexocytosis and binding of spermatozoa to the zona pellucida(ZP) [34]. ZP-induced acrosomal exocytosis in domestic ... The effects of the phytoestrogen genisteinon the postnatal development of the rat. Toxicol Sci 2003, 71,74-83.20. Mahony MC, Gwathmey T. Protein tyrosinephosphorylation during hyperactivated ... [14,17,21]. In the present study, the exposure to genistein slightly increasedsperm motile characteristics compared to the control.Fielden et al. [11] reported that the exposure to genistein at the...

báo cáo khoa học: "A statistical model for genotype determination at a major locus in a progeny test design" ppt

... females according to their genotypes : the candidate population issubdivided into three groups by minimizing the sum of squared deviations from the within group means. ... points are to be modified : the probability pi used in the successive estimations of the parameters is defined in another way and we have to calculate at each step the ... c.U! depending on the genotype of the daughter. Whatever the hypothesis, the problem of prior information on these parameters appears andrequires preliminary investigations.2....

Tài liệu Báo cáo khoa học: "Learning to Find Translations and Transliterations on the Web" doc

... and generate features for each tokens in the same way as done in the training phase. We then use the trained model to tag the snippets, and extract translation candidates by identifying consecutive ... preparing training data, we add the distance, i.e. number of words, between a Chinese token feature and the English term in question, aimed at exploiting the fact that translations tend to occur ... E is used to indicate the occurrences of the given term (e.g., Emmy Awards in Figure 1). 3.1.2 Generating translation feature. We generate translation features using external bilingual resources....

Báo cáo khoa học: Contributions to catalysis and potential interactions of the three catalytic domains in a contiguous trimeric creatine kinase doc

... changes in substrate binding, catalyticefﬁciency (kcat⁄ KM) decreased in direct relation to the kcatvalues (Table 2).These results show that the contribution of eachCK domain to catalysis ... linked to substrate binding in the second. Stated another way, formation of the TSAC in one active site may act to stabilize the openstate in the other, or preclude its closing. [5]. This ‘tug-of-war’ ... proline that seems in the rabbit crystalstructure to act as a hinge point when the N-terminalundergoes conformational changes upon conversion to the TSAC are indicated (many of the N-terminal...

Báo cáo khoa học: "What to do when lexicalization fails: parsing German with sufﬁx analysis and smoothing" doc

... to be due to Markovization. The boundaries of VPs are sometimes incorrect, with the parser attaching dependents directly to the S noderather than the VP. In the most extreme cases, the VP had ... howsmoothing can be incorporated into an unlexicalizedgrammar to achieve state-of -the- art results in Ger-man. Rather using one smoothing algorithm, we usethree different approaches, allowing us to ... becauselexicalization adds little to the performance of Ger-man parsing models, it is therefore interesting to in- vestigate the impact of smoothing on unlexicalizedparsing models for German.Parsing an...

Tài liệu Báo cáo khoa học: "You’ve Got Answers: Towards Personalized Models for Predicting Success in Community Question Answering" doc

... answer ”be” in answer Q prev avg rating”want in answer in the in question CA avg asker rating”adenocarcinoma” in question CA History “anybody” in question”was” in question ”who is” in question ... was satisﬁed.Based on our exploration we believe that the mainreasons for not “closing” a question are a) the askerloses interest in the information and b) none of the answers are satisfactory. ... participants, in- formation seekers can obtain speciﬁc answers to their questions. However, user success in obtaining satisfactory answers varies greatly.We hypothesize that satisfaction with the con-tributed...

Tài liệu Báo cáo khoa học: Site-directed mutagenesis of a loop at the active site of E1 (a2b2) of the pyruvate dehydrogenase complex A possible common sequence motif docx

... motif outlined in Fig. 2. In addition to the E1aR288A mutant of rat E1bbeing inactive, it was incapable of becoming phosphory-lated, suggesting that this residue may be involved in the interaction ... subcloninginto the vector. All the sequences differed slightly from the original pKBstE1a plasmid [21] in the noncoding regionfollowing the stop codon. The differences (four C instead ofthree C at ... recognized as involved in binding thiamindiphosphate (ThDP) in all ThDP-dependent enzymes. The role of individual residues in this set of conserved aminoacids in the E1a chain was investigated by...

Báo cáo khoa học: Site-directed mutagenesis of selected residues at the active site of aryl-alcohol oxidase, an H2O2-producing ligninolytic enzyme pot

... moleculardocking. The enzyme consists of two domains, the FAD-binding domain (bottom part) and the substrate-binding domain (top part), and one cofactor moleculewith the adenine moiety buried in the ... clustering together after docking. The putativesubstrate-binding pocket is connected to the proteinsurface by a main channel providing direct access to the re-side of the isoalloxazine ring, ... of them clustered together in front of the rectus (re)-face of the isoalloxazine ring of the FAD cofactor. This substrate location is shown in Fig. 2A, which includes the 10 molecules of veratrylalcohol...

Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx

... rate-limitingstep for folding. The linear plots in Fig. 7 indicate a bf-valueof 0.09 supporting the latter model. We see that the prolinemutations produce very small effects on the folding rate ... realized in the folding TSE, indicative of the loop between the N-terminal b-hairpin and the main a-helix remainingﬂexible in the TSE, with native-like contacts and back-bone F,w angles becoming ... structured in the transition state for folding and appear to be consolidatedinto the native structure only late in the folding process. Wedraw a similar conclusion regarding position 19 in the loopconnecting...

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