Báo cáo y học: "Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences" ppsx
... framework for perform-
ing computational analyses, systematically repeating ana-
lyses, capturing all details of performed analyses, and
annotating analyses. Using Galaxy Pages, researchers
can communicate ... When a user performs an analysis using Galaxy,
it automatically generates metadata for each analysis
step. Galaxy’s metadata includes every piece of informa-
tion necessary to...
... of a catheter in the radial artery
and either a central venous catheter and/ or a pulmonary
artery catheter (n = 14). The latter allowed to measure
the PAOP after proper wedging, the cardiac output ... peri-
cardial (regional) tamponade after primary cardiac surgery.
Theaimofthecurrentstudywasthereforetoevalu-
ate, retrospectively, the clinical, haemodynamic and
echocar...
... variation. Our data indicate
that SV discovery is largely dependent on the strategy
used, and presently there is no single approach that can
readily capture all types of variation and that a combina-
tion ... holds the Natural Sci-
ences and Engineering Research Council of Canada (NSERC) Alexander Gra-
ham Bell Canada Graduate Scholarship. DP is supported by fellowships from...
... same training and testing
for inter-rater reliability. The raters explained the proce-
dure and human rights to the prospective subjects and
obtained informed consent. Then they administered the
structured ... opportunities for intimacy safely from
the beginning of therapy. A second lesson is that doing so
may be also necessary for therapy.
So far, the stepwise outco...
... A, Yamada R, Chang X, Tokuhiro S, Sawada T, Suzuki M,
Nagasaki M, Nakayama-Hamada M, Kawaida R, Ono M, Ohtsuki
M, Furukawa H, Yoshino S, Yukioka M, Tohma S, Matsubara T,
Wakitani S, Teshima R, ... S, Teshima R, Nishioka Y, Sekine A, Iida A, Takahashi A,
Tsunoda T, Nakamura Y, Yamamoto K: Functional haplotypes of
Arthritis Research & Therapy Vol 6 No 1 Vossenaar et al.
... cytoki...
... injury has anti-
inflammatory effects [5].
In the current paper by Schwartz and colleagues, TWEAK
was assessed as a biomarker for LN in both cross-sectional
and longitudinal studies. In the former, ... array of
cytokines, chemokines and cell adhesion molecules. TWEAK
plays a role in tissue inflammation, repair and regeneration in
many diseases, including SLE [5]....
... (approxi-
mately 90%) are shared (Additional data file 3) since they
encode proteins displaying at least 30% amino acid identity
over at least 80% of their length and are, in addition, in syn-
teny ... points in the query genome in comparison with
closely related genomes, searches for mobility genes, tRNA
and direct repeats (if any) at the borders of the synteny break
poin...
... two
‘expected’ values: one is calculated analytically and the
other empirically. The first quantity is DASPER (the dif-
ference between the observed and analytically calculated
expected SPER), indicating ... selected as potential candidate fusion tran-
scripts; also, reads that do not align anywhere are stored
for the computational validation of the candidates and
for d...
... ated
laboratory and imaging data, and assisted with manuscript
editing. MS and SK collected the patient’s information.
YM was the pathologist and performed the histological
examinations. All authors ... cytokines and protei-
nases. TNF -a is a key cytokine, which triggers the
inflammatory cascade and stimulates the production of
matrix degradable proteinases such as m...
...
reagent to check the non-specific binding of the
CD34-PE monoclonal antibody.
Statistical analysis
All data were analyzed by Systat software (Sys-
tat Inc) and KaleidaGraph software. Variables ... parameters are
summarized in Table 1.
These percentages did not vary systematically
with the initial mass of the subjects. The decrease in
body fat was substantial, and in...