Báo cáo y học: " Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cells" pdf
Báo cáo y học: " Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cells" pdf
... Open Access Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cellsThomas K Albert1, Korbinian Grote 2 , Stefan Boeing1, Michael ... prevalence for the occurrence of motif com-binations in TFIIB-dominated genes in illustrated in Figure5e.InlinewiththeknownsynergybetweenINR and TATA [14], 94% and 56% of promoters harboring the INR motif ... for one initial cycle con-sisting of 2 minutes at 55° (during which polymerasewas added), 5 minutes at 72 C and 2 minutes at 94°C,followed by 22 cycles of 0.5 minutes at 94°C, 0.5 min-utes...
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Báo cáo y học: " Highly pathogenic avian influenza A virus H5N1 NS1 protein induces caspase-dependent apoptosis in human alveolar basal epithelial cells" docx
... 1998, 25 2: 324 -330. 23 . Hyland L, Webby R, Sandbulte MR, Clarke B, Hou S: Influenza virus NS1protein protects against lymphohematopoietic pathogenesis in an in vivo mouse model. Virology 20 06, ... signaling responses. J Virol 20 07,81:3058-3067. 28 . Hayman A, Comely S, Lackenby A, Murphy S, McCauley J, Goodbourn S,Barclay W: Variation in the ability of human influenza A viruses to induce and ... NCI-H2 92, was caspasepathway-dependent [26 ]. Here, we performed experi-ments to investigate whether the caspase pathways wereinvolved in the apoptosis induced by NS1 proteinsderived from the influenza...
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Báo cáo y học: "Food allergy management from the perspective of patients or caregivers, and allergists: a qualitative study" docx
... allergy. J Allergy Clin Immunol 20 10, 125 (2 Suppl 2) :S116 -25 , Epub 20 09 Dec 29 . Review. 2. Salter J, Mehra S, Cairns JT, Sussman G, Vadas P: A study of 32 food-induced anaphylaxis deaths in Ontario: ... wereseen in US mortality data recorded by the AmericanAcademy of Allergy, Asthma & I mmunology: between 1994 and 1999, only 3 of 32 individuals had epinephrineavailable for use at the time of their ... provid ed the original work is properly cited.A subsequ ent study found t hat of the 31 additionaldeaths between 20 01 and 20 06, only 4 individuals hadepinephrine administered in a timely manner...
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Báo cáo y học: "Tumour necrosis factor activates the mitogen-activated protein kinases p38α and ERK in the synovial membrane in vivo" doc
... also in the syn-ovial lining layer (Fig. 2a,b,d,e). In contrast, activation of JNKwas far less frequent and confined to a few cells within syno-vial pannus and the synovial lining (Fig. 2c,f). ... byproinflammatory cytokines, which not only induce but alsomaintain synovitis and therefore play an important role in pro-gressive joint destruction [1 ,2] . Several cytokines are currentlyconsidered ... factor in chronic synovial inflammation and is an inducer of mitogen-activated protein kinase (MAPK) signalling. In the present studywe investigated the ability of TNF to activate MAPKs in the synovial...
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Báo cáo y học: "Risk factors associated with the loss of cartilage volume on weight-bearing areas in knee osteoarthritis patients assessed by quantitative magnetic resonance imaging: a longitudinal study" pot
... meniscectomy [31]. Taken together, these find-ings stress the very important role played by the meniscalstructure and positioning in protecting the integrity of cartilage in both healthy and OA individuals. ... (Table 1). Theseare in line with some of our findings from previous analyses [2, 7] and with the work of other investigators [9,11 ,28 ,29 ].There are, however, some exceptions. For instance, the asso-Table ... compartment and the JSW in patients with knee OA.These findings were in line with the previous report of Amin and colleagues [4]. However, in the present study, a verystrong correlation was found between...
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Báo cáo y học: " Factors that may mediate the relationship between physical activity and the risk for developing knee osteoarthritis" pot
... involvement in heavy physicalactivity increases their risk. Further longitudinal investigationthat accurately examines the level of physical activity in obeseindividuals is required to confirm these ... study.Assessment of physical activity is further complicated by the different features of physical activity, including the type,intensity, frequency and duration, that can be examined. Forinstance, although ... biomechanics and bodycomposition may influence the effect of physical activity onjoint health. Overall, these findings highlight the need toconsider the role of sex when examining the relationshipbetween...
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Báo cáo y học: "Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic nois" pdf
... significantly reduce the range of random pheno-typic variability. Simil arly, moving the animal s into the wild to increase environmental variability did notincrease random phenotypic variability, hence ... phenotypes in Trim28MommeD9/+mice.A recent study of a Trim28 conditional knockout in the forebrain reported heightened anxiety and stress-inducedbehavior in mutant animals [22 ]. We tested the ... =4) was assessed for integrity using the Agilent Bioanalyzer 21 00, and RNA integrity (RIN) scores above 8 w ere pre-sent in all samples. RNA was amplified using the IlluminaTotalPrep RNA Amplification...
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Báo cáo y học: "Tumor necrosis factor-a enhances hyperbaric oxygen-induced visfatin expression via JNK pathway in human coronary arterial endothelial cells" ppt
... inhibit the visfatin protein expression induced byHBO.ThesefindingsimplicatedthatJNKandERKpathways but not p38 MAP kinase and PI-3 kinasemediated the induction of visfatin protein by HBO in Control 15 2 25(ATA)HBO, ... antibody and SP600 125 inhibited the AP-1 binding activity inducedby HBO, indicating that TNF-a and JNK pathway mediate the increased transcriptional activity of AP-1 in the HBOmodel. Furthermore, ... Y: The metabolic syndrome and adipocytokines. FEBS Lett 20 06, 580 :29 17 -29 21. 2. Matsuzawa Y: Therapy insight: adipocytokines in metabolic syndrome and related cardiovascular disease. Nat Clin...
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Báo cáo y học: "Eyes wide shut - unusual two stage repair of pectus excavatum and annuloaortic ectasia in a 37 year old marfan patient: case report." pdf
... pul-monary function testing and cardio-pulmonary exercisetesting are suggested. However, the extent of physic alund especially image-guided examinations is generallyon discretion of the physician in ... the arch and venouscannulation using a two-stage cannula placed into the right atrium cardiopulmonary bypass was started. The ascending aort a was distally crossclamped directlyunderneath the ... twometal bars. They were placed in a parallel fashion with the ends supported by the lateral thorax at the level of the third and fourth rib and fixed with ripclamps. The middle portion of the chest...
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Báo cáo y học: "An MRI study on the relations between muscle atrophy, shoulder function and glenohumeral deformity in shoulders of children with obstetric brachial plexus injury" ppt
... following hypothesis to explain the differ-ence in atrophy between infraspinatus and subscapularis.We suggest that the infraspinatus muscle is more affectedby denervation than the subscapularis ... prospective study in OBPL chil-dren between 1 .2 and 7.3 years to assess the relations between muscle atrophy, glenohumeral deformity and passive and active shoulder function in OBPL. The activefunction ... were assessed between 1998 and 20 03. The children underwent MR imaging, the younger chil-dren while being sedated. Their position was standardizedwith both hands on the belly. The shoulders...
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