Báo cáo y học: " High-resolution transcription atlas of the mitotic cell cycle in budding yeast" pptx
Báo cáo y học: " High-resolution transcription atlas of the mitotic cell cycle in budding yeast" pptx
... is mainly containedwithin the protein-coding message; 2 of these 8 cycle in- phase, and 6 display opposite-phase expression. For 5 of 24 SAPs in which only the antisense transcript cycles, the ... phase-specific splicing; hence, in contrast tomeiosis in budding and fission yeast [49,50], we see noevidence for a regulatory role of splicing in the mitotic cell cycle of budding yeast.ConclusionsOur ... facili-tate initiation of mitosis. Samples were collected every 5minutes for 200 minutes (equal to three cell cycles). The degree o f synchrony was monitored by assessing the number of budding cells.Nuclearpositionwasdetermined...
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Báo cáo y học: "Genome-wide analysis of the diatom cell cycle unveils a novel type of cyclins involved in environmental signaling" pptx
... diatom specific.CYCB2CYCA/B;1CYCB1CYCD1CYCH1CYCP2CYCP6CYCP3CYCP4CYCP5CYCL1CYCP1CYC-likedsCYC3dsCYC4dsCYC2dsCYC10dsCYC6dsCYC8dsCYC1dsCYC9dsCYC5dsCYC7dsCYC11(b)(a)0h1h6h5h4h3h2h8h9h7h10h11h12h0h1h6h5h4h3h2h8h9h7h10h11h12h-3.0 ... Thus, increasedmRNA levels of early cell cycle- regulated genes are to beexpected at the time of cell cycle reinitiation after nitraterepletion. Accordingly, early cell cycle genes (CYCP6,CYCH1, ... expansion of the cyclin gene family in diatoms and discovered a new cyclinclass, the diatom-specific cyclins. The latter are most prob-ably involved in signal integration to the cell cycle becausetranscript...
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Báo cáo y học: "High synovial expression of the inhibitory FcγRIIb in rheumatoid arthritis" ppsx
... demonstrating FcγRI, II and III positive cells in the synovial lining and sub-lining layers and perivasculary. Note the dense staining of FcγRIII in the synovial lining layer. The FcγR stainings ... in all the stained RA synovial biopsies. FcγRIIb staining was observed in the synovial lin-ing and sub-lining layers, perivasculary and inside lymphocyte infiltrates (e). (d) No staining of ... however,most often in the synovial lining layer and in the sub-lininglayer. However, FcγRIII was not detected as often as FcγRII in the sub-lining layer. Both FcγRII and III were occasionallydetected...
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Báo cáo y học: "Composition and conservation of the mRNA-degrading machinery in bacteria" pps
... serving as astorehouse of genetic information, the fraction of totalRNA that delivers coding information to the protein-synthesizing machinery (i.e. mRNA ) is in trinsically labileand continuously ... in bacteria, the degree of their coupling cancontrol the access of individual transcripts to the RNAdecay machinery, thus influencing the rate of mRNAturnover. For more information about the ... 1).Since the steady-state level of mRNA ca n vary and is afunction of RNA synthesis and decay, the control of mRNA stability plays an essential role in the regulation of gene expression. As transcription...
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Báo cáo khoa học: Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex doc
... early in the cell cycle (before RP) immediately suffer a long delay in the cell division cycle; (b) cells treated late in the divi-sion cycle finish the current cycle similar to untreatedcells ... Novak andTyson [5] constructed their kinetic model on the RP of the mammalian cell cycle using a yeast-like core model of the cyclin–Cdk interactions (emphasizing the deepsimilarities of the Cdk-regulatory ... phosphorylation of Rb is induced by Cdk/cyclincomplexes. (D) P27, a cyclin-dependent kinase inhibitor in the G1-phase, also binds to cyclin A/Cdk2 (CYCA) and cyclin E/Cdk2(CYCE) dimers to form inactive...
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Báo cáo y học: "Predictive network modeling of the highresolution dynamic plant transcriptome in response to nitrate" pps
... Tsay YF: CHL1 functions as a nitrate sensor in plants. Cell 2009, 138:1184-1194.21. Hu HC, Wang YY, Tsay YF: AtCIPK8, a CBL-interacting protein kinase,regulates the low-affinity phase of the ... the type of microarray data normalization, and the optimization algorithm for learning the parameters of the dynamical model. For each of these, we selected the best hyperparameters, namely the ... corresponding to the beginning of sentinel geneinduction and their preceding time points (0, 3, 6, 9, 12,15, 20 minutes). Note that we kept the 20-minute timepoint as a referenc e, since it was the...
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Báo cáo y học: "Clinical review: Treatment of new-onset atrial fibrillation in medical intensive care patients – a clinical framework"
... associated with increasedmorbidity. This is reflected by the number of reportedsymptoms and by the days spent in the ICU and in the hospital. Haemodynamic parameters also tend to be worse in patients ... optimising the fluid balance, correcting electro-lyte disturbances, reducing sympaticus tonus and avoidingproarrhythmic drugs. Reduction of the systemic inflammatorystate is tempting but is of ... RA, Almere, The Netherlands2Department of Intensive Care, University Medical Center Groningen, University of Groningen, PO 30.001, 9700 RB Groningen, The Netherlands3Department of Intensive...
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Báo cáo y học: "Aplasia and Agenesis of the Frontal Sinus in Turkish Individuals: A Retrospective Study Using Dental Volumetric Tomograph"
... age of 8 years, the top of the frontal sinuses is at the level of the orbital roof, and by the age of 10 years, the sinuses extend into the vertical portion of the frontal bone. The final adult ... By the age of 4 years, the average cranial extent of the frontal sinus reaches half the height of the orbit and extends just above the top of the most-anterior ethmoid cells. By the age of ... craniotomy because of the proximity of the sinus to the orbit and the anterior skull base [5]. The frequency of bilateral absence of the frontal sinus has been reported in 3-4% to 10% of several...
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Báo cáo y học: " Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial"
... including glucosamine and chondroitin, one month prior to study and during the study, other than multivitamin and mineral supplements containing vitamins and minerals as the sole medicinal ingredients ... unwilling to stop taking pain medication other than the study medication (for arthritis or other types of pain) or is unwilling to stop taking other medications for the treatment of OA Any other ... present clinical trial evaluated the safety and efficacy of UC-II as compared to a combination of glucosamine and chondroitin (G+C) in the treatment of OA of the knee. The results indicate that...
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Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx
... residue and/or by the binding contribution fromtheGalNAcresidue.Docking the glycopeptide to the antibody the sugar ringhas little contact to the protein surface. Only the N-acetylmethyl group is ... struc-ture into the binding cavity of SM3 and the binding epitopeobtained from STD NMR is very good.Comparison with the X-ray and previous NMR structuresAs mentioned above, in the crystal cell the ... 36% of the interaction of the full peptide with the binding cavity of SM3. The sizes of the surfaces were determined using distances between ligandatoms and protein atoms of less than 3 A˚. These...
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