... used asa tool for (a) increasing the catalytic efficiency of enzymes in the biotechnology industry (by enhancing the coupling ofdynamics to the reaction coordinate), and (b) producingmore effective ... nss4@le.ac.ukAbbreviations:TST,transitionstatetheory;TTQ,tryptophantrypto-phylquinone; MADH, methylamine dehydrogenase; AADH, aroma-tic amine dehydrogenase; TMADH, trimethylamine dehydrogenase;TSOX, heterotetrameric sarcosine dehydrogenase; ... enzyme inhibitors in the pharmaceuticalindustry (by dampening those vibrations coupled to thereaction coordinate). Such advances have broader implica-tions, as they will also give insight into...