Báo cáo y học: "Serum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycle" doc
Báo cáo y học: "Serum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycle" doc
... properly cited.Ras isoforms and the cell cycle<p> ;Transcriptional and functional analysis reveals that the H-Ras and N-Ras isoforms have different roles in the initial phases of the mouse cell ... confirm the notion of an absolute requirement for different peaks of Ras activity during the initial stages of the cell cycle and document the functional specificity of H-Ras and N-Ras during ... R123ResearchSerum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycleEsther Castellano*†, Carmen Guerrero*, Alejandro Núñez*,...
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Báo cáo y học: "Prior exposure to an attenuated Listeria vaccine does not reduce immunogenicity: pre-clinical assessment of the efficacy of a Listeria vaccine in the induction of immune responses against HIV" pps
... meancompared to the sera of 6 naïve monkeys. No increaseswere observed during the course of the immunization inany monkeys (Table 1 and 2). We also screened for anti-Gag IgG responses by using ELISA ... list of author information is available at the end of the articleWhitney et al. Journal of Immune Based Therapies and Vaccines 2011, 9:2http://www.jibtherapies.com/content/9/1/2© 2011 Whitney ... Gagprotein. The efficacy of the Lm vector was determined by ELISA to assess the generation of anti-Listerial antibodies;cellular responses were measured by HIV-Gag specific ELISpot assay. Our results...
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Báo cáo khoa học: " 3D-conformal-intensity modulated radiotherapy with compensators for head and neck cancer: clinical results of normal tissue sparing" doc
... Academy of Otolaryngology-Head and NeckSurgery: Neck dissection Classificaton Update: Revisions Pro-posed by the American Head and Neck Society and the American Academy of Otolaryngology-Head and ... assigned for inverse planning: the parotid glands, the spinal cord with5 mm safety margin, brain stem and more recently the glottic larynx without any safety margin. The mandible and oral cavity were ... change of the composition of the oral flora being the most important [11]. Due to their ease detectibility inplanning CT, their lateral position and their pairity theyhave been selected early when...
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Báo cáo y học: "Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis" ppsx
... indicated by a spot, with the intensity of the spot representing the proportion of significantly differentially expressed transcripts for each one of the transcriptional modules. The color of the spot ... accuracy as before, despite the change of microarray platform. (b) The performance of the 37 predictor genes was then further evaluated in a secondary independent test set also analyzed using ... funded by the Baylor Health Care System foundation and the National Institutes of Health (U19 AIO57234-02 and U01 AI082110 toJB) and the NIAID/NIH (AI-61363). RP was supported by the Commissionof...
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Báo cáo y học: "Identifying transcriptional targets" pdf
... anothergroup has designed a microarray containing the non-repetitivesequence of human chromosome 22 [27]. They then used thisarray in a ChIP assay to analyze binding of the p65 subunit of NF-B ... expression of a hormone-inducible form of Clk in cell culture in the presence of cycloheximide indicatesthat only nine of the genes are in fact direct targets [7].These methods provide further evidence ... At this point, the isolated DNA can be used to verify targets by PCRor dot blot, or the DNA may be sub-cloned and sequenced to identify new targets [44]. For ChIP array analysis, the purified...
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Báo cáo y học: "Information exchange networks for chronic illness care in primary care practices: an observational study" pptx
... omparison and role modeling, although obviously the quality of the connections plays a role as well.It is unclear whether these and other hypotheses on the uptake of innovations apply to healthcare. ... conditions,asopposedtoCHF.ItmayalsoreflectthestrongerfocusondiabetesandCOPD,comparedtoCHF,innat ionwide programmes for quality improvement in the Netherlands. The lower density of the CHF network inthepracticesmayprovideachallengefortheuptakeofnew ... density and centralization, were determined for the two prac-tices in the study. The study illustrated the approachvery well, but the methods used were resource intensive and time consuming.In the...
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Báo cáo y học: " Post-transcriptional control by bacteriophage T4: mRNA decay and inhibition of translation initiation" pdf
... he encodes the 5’ strand of the RNA structure. Therefore, early translation of these lysisgenes may also be inhibited by intramolecular RNAstructures (Figure 5). The T4 thymidylate synthase gene ... polynucleotide kinase/3’ phos-phatase (PNK). This enzyme catalyzes both the phos-phorylation of 5’-hydroxyl polynucleotide termini and the hydrolysis of 3’ -phosphomonoesters and 2’ :3’-cycl ... aselaborated by the Utah group. Some of principal featuresinclude: a domain of the nascent gp60 polypeptide preced-ing the hop, the glyc ine 46 codon GGA at the end of the initial ORF (the “take-off...
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Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
... protein profile of the serum samples from the 98 patients with CRC and the 80 healthy controls were extracted by magnetic beads and examined by MALDI-TOF-MS. The data were analyzed by Bio-marker ... the sensitivity of 92.85% and the specificity of 91.25%. Blind test data indicated a sensitivity of 86.95% and a specificity of 85%. The result suggested that MALDI technology could be used ... were approved by the local Ethics Committee of Taizhou Municipal Hospital, and had the informed consent of the patients and volun-teers. The patients and serum samples were then di-vided...
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Báo cáo y học: "1, 25-dihydroxyvitamin D3 decreases adriamycin-induced podocyte apoptosis and loss"
... beneficial effects of 1,25(OH)2D3 on podocytes may be attributable to inhibit podocyte apoptosis and the amelioration of podocytopenia. Key words: 1, 25 -dihydroxyvitamin D3, podoc yte, proteinuria ... podocyte apoptosis and podocyto-penia. The present study aimed to investigate the ef-fects of 1,25-(OH)2D3 on podocyte apoptosis and po-docytopenia induced by adriamycin (ADR) and the potential ... micro-scopy. The number of apoptotic podocytes per glomerulus and that of apoptotic nuclei an d caspase-3 activity in cultured podocytes were determined by TUNEL staining. The average number of podocytes...
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Báo cáo y học: "Line bisection performance in patients with generalized anxiety disorder and treatment-resistant depressionLine bisection performance in patients with generalized anxiety disorder and treatment-resistant depression"
... team work includes the clin-ical psychology and clinical psychiatry, being funded by the Natural Science Founda-tion of China, the H.J. Ey-senck Memorial Foundation, and others. Int. J. ... Department of Clinical Psychology and Psychiatry, Zhejiang University School of Medicine, Hangzhou, China; 3. Department of Psychiatry, Second Hospital, Zhejiang University School of Medicine, ... midpoint to the right of the true center 4. Of interest to psychologists and psychiatrists are the possible functional cerebral asymmetries represented in sorts of psychiatric patients and in...
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