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Báo cáo y học: "The promise and reality of personal genomics" pot

Báo cáo Y học: The processivity and fidelity of DNA synthesis exhibited by the reverse transcriptase of bovine leukemia virus pot

Báo cáo Y học: The processivity and fidelity of DNA synthesis exhibited by the reverse transcriptase of bovine leukemia virus pot

... The processivity and fidelity of DNA synthesis exhibited by the reverse transcriptase of bovine leukemia virus Orna Avidan, Michal Entin Meer, Iris Oz and Amnon HiziDepartment of Cell Biology ... processivity of DNA synthesis and the fidelity of DNA synthesis. Theseproperties were c ompared with t hose o f the well-studied RTs of human immunodeficiency virus type 1 (HIV-1) and murine leukaemia virus ... Both the elongation of the DNA template and the processivity of DNA synthesis exhibited by BLV RT are impaired relative to the other twoRTs studied. Two parameters of fidelity were studied, the capacity...
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Báo cáo y học: "The use and abuse of commercial kits used to detect autoantibodies" ppsx

... high level of security, of scrutiny and of standardization, and under good labora-tory practices and quality control. Many of these compa-nies subscribe to and offer postmarketing qualityassurance ... chain of production, use and application of autoantibody test kits. 198PatientThe ongoing demands of quality control and quality assur-ance are highly dependent on the availability of prototypesera ... specificity), reliability, and quality of many commercial kits. In many cases the manu-facturer has been assumed the root cause for these short-comings; however, the use of commercial kits and theirappropriate...
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Báo cáo y học: "The identification and characterization of a novel protein, c19orf10, in the synovium" docx

... (f) An area of an OA synovium demonstrates a lining layer completely devoid of c19orf10 staining. (g) Intense staining of a hyperplastic RA synovial lin-ing cell layer. This staining was typical ... Expression of c19orf10 in OA synovium. (a) Intense staining of the synovial lining layer and perivascular regions of RA (OCT sec-tion) tissue.(b) Intense staining of the synovial lining layer and ... minimal staining of the lymphocytes although some mononuclear cells in the aggregates stained positively (arrow). (e) Intense staining of individual cells in the lining layer of a typical OA synovium....
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Báo cáo y học: "The promise and reality of personal genomics" pot

... (Solexa) [4] and Applied Biosystem’s SOLiD [5] systems - but no explicit comparison of the two versions has yet been published.MinireviewThe promise and reality of personal genomicsBryndis Yngvadottir, ... likely to be easy to both genotype and sequence. The sensitivity of SNP and indel detection in repetitive or copy-number-variable regions will be lower. Finally, a non-trivial proportion of any ... Lower section: expanded view of the personal genome inferred ancestries.Bantu (South Africa)Bantu (Kenya)YorubaYRI (HapMap)MandenkaBiaka PygmiesSanNA18507VenterWatsonYHAK1SJKAfricaEurope...
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Báo cáo y học: " The yin and yang of chromatin spatial organization" ppt

... of chromatin may extend away from the core of the territory. (d) As G1 phase is established and nucleoli form, loops of NOR-containing chromatin co-associate with the other components of the ... nuclear lamina. These processes, along with others described in this article and many more, are likely be important in dynamically shaping the spatial environment and organization of the genome.Specialized ... non-random. Preferential chromatin interactions, both in cis and in trans and between transcriptionally active and silent regions, inuence organization.â 2010 BioMed Central Ltd The yin and yang...
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Báo cáo y học: "The promise and limitations of population exomics for human evolution studies" doc

... variation and evolutionary history, but there are signicant challenges to overcome before this becomes a reality.â 2010 BioMed Central LtdThe promise and limitations of population exomics for human ... events (in units of thousands of years, kyr) and population sizes are indicated. (b) The site frequency spectrum for sample sizes of 50 and 2,000 chromosomes. (c) Average value of Tajima’s D ... clearly more desirable and important to develop [33].Challenges and caveats for population exomics Although exome datasets remove many of the biases and limitations that have plagued previous population...
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Báo cáo y học: " The prevalence and correlates of adult separation anxiety disorder in an anxiety clinic" pptx

... patients to DSM-IV adult anxiety subcategories using the SCID. We also measured demographic factors and reports of early separation anxiety (the Separation Anxiety Symptom Inventory and a retrospective ... played a major role in designing the study from its inception, directing the analyses and made a key contribution to writing and refining the article.CM, VM and RW contributed to the design and ... ASAD attending an anxiety clinic are highly symptomatic and disabled. The findingshave implications for the classification, clinic al identification and treatment of adult anxiety disorders.BackgroundThe...
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Báo cáo y học: " The identification and management of ADHD offenders within the criminal justice system: a consensus statement from the UK Adult ADHD Network and criminal justice agencies" doc

... al.: The identification and management of ADHD offenders within the criminal justice system: a consensus statement from the UK Adult ADHD Network and criminal justice agencies. BMC Psychiatry 2011 ... adult ADHD and the Criminal Justice System (CJS) will be vital toraising awareness of the needs of ADHD offenders at every stage of the offender pathway. Joint working and commissioning within the ... Eli-Lilly, Janssen-Cilag,Pharmacia Upjohn and UCB Pharma; JT at meetings sponsored by Janssen-Cilag and Eli-Lilly; and PA at meetings sponsored by Janssen-Cilag, Shire and Flynn-Pharma.SY has received...
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Báo cáo y học: "The infectivity and pathogenicity of a foot-and-mouth disease virus persistent infection strain from oesophageal-pharyngeal fluid of a Chinese cattle in 2010" potx

... p.i The infectivity and pathogenicity of a foot- and- mouth disease virus persistent infection strain from oesophageal-pharyngeal fluid of a Chinese cattle in 2010 ArticleCategory : Short ... circulated strain O/CHN/Mya98/2010. Keywords Foot -and- mouth disease virus (FMDV), Persistent infection strain, Oesophageal-pharyngeal fluid, Infectivity, Pathogenicity Findings Foot -and mouth ... Key Laboratory of Veterinary Etiologic Biology, Key laboratory of Animal Virology of Ministry of Agriculture, National Foot- and -Mouth Disease Reference Laboratory of China, Lanzhou Figure...
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Báo cáo y học: "The expression and significance of protooncogene c-fos in viral myocarditis" pot

... expression in the cardiomyocytes of VMC mice is significantly increased, c-fos plays animportant role in myocardial lesions. The apparent increase in expression of c-fos is likely to be involved in ... Ruiz4AbstractBackground: c-fos may play a role in the pathogenesis of some diseases. The expression and function of c-fos in viral myocarditis (VMC) have not yet been reported. To study the change and significance of ... pathogenesis of VMC.Conclusions c-fos expression in the cardiomyocytes of VMC mice issignificantly increased, c-fos plays an important role in myocardial lesions. The appar ent increase in expression of...
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Báo cáo y học: " The establishment and characterization of the first canine hepatocellular carcinoma cell line, which resembles human oncogenic expression patterns" ppsx

... Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands and 3Department of Infectious Diseases and Immunology, Division of Virology, Faculty of Veterinary Medicine, ... with the neoplastic nature of the cells [11], and suggests the presence of both fully differentiated hepato-cytes and progenitor cells in the cHCC cell culture. The hepatocytic nature of the ... 1 of 10(page number not for citation purposes)Comparative HepatologyOpen AccessResearch The establishment and characterization of the first canine hepatocellular carcinoma cell line, which...
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Báo cáo y học: "The occurrence and nature of early signs of schizophrenia and psychotic mood disorders among former child and adolescent psychiatric patients followed into adulthood" docx

... purposes) Child and Adolescent Psychiatry and Mental HealthOpen AccessResearchThe occurrence and nature of early signs of schizophrenia and psychotic mood disorders among former child and adolescent ... Psychotic mood disorders& quot;. Clearly psychotic mood disorders are rare among children and adolescents.Individuals experiencing early onset of disorders catego-rized as "F20–F29: Schizophrenia, ... "F20–29: Schizophrenia, schizotypal and delusional disorders& quot; may already exhibit typical symptoms upon admission to child and adolescent psychiatric care of the age of 13–17; whereas late-onset disorders it...
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Báo cáo y học: "The change and effect of endothelial progenitor cells in pig with multiple organ dysfunction syndromes" ppt

... 1Number of endothelial progenitor cells during progression of multiple organ dysfunction syndromesNumber of endothelial progenitor cells during progression of multiple organ dysfunction syndromes. ... progression of multiple organ dysfunction syndromesAngiogenic capacity of endothelial progenitor cells during progression of multiple organ dysfunction syndromes. The angiogenic capacity of endothelial ... endothelial progenitor cells during progression of multiple organ dysfunction syndromesMigratory and adhesive capacities of endothelial progenitor cells during progression of multiple organ dysfunction...
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Báo cáo y học: "The ups and downs of biological timers" pdf

... sensitivity in all cases (fig. 1). c-e, Delay time sen-sitivity as a function of η and PT for the cases of accumulation (c), decay (d) and non-linear decay (e). The logarithm of the delay time ... sensitivity of the delay time is smallest for non-linear decay and largest for accumulation. b, η = 2. Also here the sensitivity of the delay time is smallest for non-linear decay and largest ... CentralPage 1 of 7(page number not for citation purposes)Theoretical Biology and Medical ModellingOpen AccessResearchThe ups and downs of biological timersNoa Rappaport, Shay Winter and Naama...
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Báo cáo y học: " The performance and assessment of hospital trauma teams" ppt

... organised model of care. The trauma team represents only one facet of the trauma system and separating the relative merits or drawbacks of the trauma team in isolation of the trauma system isnot ... madebythetraumateam.Thismaybeovercomebyadirectvital sign stream to the video or by review of the medi-cal records. The audio quality may be poor and analysis of events outside the field of view ... lack of ongoing improvement in the last six years of the twenti-eth century [6], rec ommending amongst other things, the introduction of a system of trauma audit and the establishment of hospital...
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