... Access
2004Fayet al.Volume 5, Issue 4, Article R26
Research
Population genetic variation in gene expression is associated with
phenotypic variation in Saccharomyces cerevisiae
Justin C Fay
*§
, Heather ... expression is associated with phenotypic variation in Saccharomyces cerevisiaeThe relationship between genetic variation in gene express...
... silencing of viral
genes, including the oncoprotein Tax, is associated with tumor onset.
Conclusion: Our findings suggest that silencing is critical for tumor progression and identify two distinct
mechanisms -genetic ... these findings suggest that besides
genetic changes, epigenetic mechanisms such as DNA
methylation and chromatin modifications might be
involved in tumor -associ...
... expression
expression is associated with
is associated with is associated with
is associated with good
good good
good prognosis in
prognosis in prognosis in
prognosis in
gastric cancer
gastric ...
performed in triplicate.
Immunohistochemical staining
Immunohistochemical stainingImmunohistochemical staining
Immunohistochemical staining
A...
... α-sma
Figure 1
Haematoxylin and eosin staining on healthy and arthritic synovial tissueHaematoxylin and eosin staining on healthy and arthritic synovial tissue. Haematoxylin and eosin staining was performed ... both the
lining and the sublining adjacent to the lining. This same stain-
ing pattern is found for collagen type IV. This observation
implies that, in RA patients, cells from the...
... OA, and
genetic variations in the ER-α gene may be involved in OA.
Keywords: estrogen receptor, haplotype, knee osteoarthritis, polymorphism
Introduction
Osteoarthritis (OA) is a common disorder ... BtgI polymorphism (codon 594) in the ER-α
gene and ER-α haplotypes of three polymorphisms (PvuII in
intron 1, XbaI in intron 1, and BtgI in exon 8) with primary
knee OA in...
... 1–4, weak staining; 5–8, moderate staining;
and 9–12, strong staining. For the purpose of statistical
analysis, the cohort was grouped into tumors with negli-
gible or weak staining (N = 34) ... and cisplatin.
Of the 221 patients, 88 were referred for treatment from a
single institution following initial diagnosis of NPC. For
logistic reasons, only patients from this hospital were
included...
... vitronec-
tin, fibronectin, osteopontin, sialoprotein, thrombospondin,
fibrinogen, von Willebrand factor, tenascin, agrin, matrix metal-
loproteinases, and prothrombin) [6]. The integrins are involved
in ... reproduction in any medium, provided the original work is properly cited.
Abstract
The integrin αvβ3, whose αv subunit is encoded by the ITGAV
gene, plays a key role in angioge...
... must arise during spermiogenesis since this
is when the NPYq-encoded genes are expressed in nor-
mal mice [3,5,28]. In keeping with the two step model
for the generation of DNA damage in epididymal ... compac-
tion. In addition to demonstrating the involvement of
NPYq-encoded genes in regulating chromatin remodel-
ing during spermiogenesis, the study also provides
important insi...
... Bayesian sta-
tistics that allows the integration of data from
heterogeneous sources. Integration is important because
with expression data alone it is difficult to distinguish
direct from indirect ... We
have also integrated information about binding motifs at
promoters. Doubtless, the dominant feature in our classi-
fication is gene expression. This is, however, rather spe-...
... nuclear staining of STAT3, and 24 cases (32.4%)
with strong nuclear staining of P-STAT3. Representative
staining outcomes were shown in Figure 1. There
existed a consistence between the STAT3 expression
and ... angiogenesis [11]. Hypermethylation
silencing of SOCS (the Suppressor of Cytokine Signal-
ing) genes leads to reactivation of STAT pathway,
resulting in the resistance to ABT-8...