Báo cáo sinh học: "ECM approaches to heteroskedastic mixed models with constant variance ratios" docx
Báo cáo sinh học: "ECM approaches to heteroskedastic mixed models with constant variance ratios" docx
... of squares (¿ y2) in each suclass.Original articleECM approaches to heteroskedastic mixed models with constant variance ratiosJL FoulleyStation de génétique quantitative ... easily generalized to several independent random factorsif conditional maximization is performed factor by factor. The system [AI8] applies to each factor k with APPENDIX B: ... San Cristobal M, Gianola D, Im S (1992) Marginal likelihood and Bayesian approaches to the analysis of heterogeneous residual variances in mixed linear Gaussian models. Comput...
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Báo cáo sinh học: " Inference about multiplicative heteroskedastic components of variance in a mixed linear Gaussian model with an application to beef cattle breeding" docx
... cycles for heteroskedastic T e -models with <7J estimated by EM-R.EML ((i) stage), and 15-40cycles for fully heteroskedastic T -models or heteroskedastic T e -models with randomeffects. ... due to poor accuracy of within herd or herd-yearvariances (Brotherstone and Hill, 1986). It then suffices to use a hierarchical (linear) mixed model for herd log-variances ... interesting to extend our method to a fully generalized linear mixed model on means and on variances with or without common parameters betweenthe mean model and the variance...
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Tài liệu Báo cáo khoa học: Chemical approaches to mapping the function of post-translational modifications ppt
... binding was detected with themouse innate immunity protein DC-SIGN-R2. Thissynthetic protein probe also selectively bound to thenuclei of a neuron subpopulation, with no binding to the nuclei of ... common to organic synthesis but not yet amenable to proteinmodification. As new methodologies emerge, the studyof other PTMs and that of regulatory PTMs will hope-fully provide a powerful tool ... oligosaccharideassembly in the yeast Pichia pastoris: production ofcomplex humanized glycoproteins with terminal galac-tose. Glycobiology 14, 757–766.20 Hamilton SR, Bobrowicz P, Bobrowicz B, DavidsonRC,...
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Tài liệu Báo cáo khoa học: Combinatorial approaches to protein stability and structure pdf
... long day), we want to be able both to understand what makes proteins ÔtickÕ andtoengineerproteins with native-like properties.In this review we discuss combinatorial approaches toward understanding ... genes must be pieced together with PCR-basedmethods. Using mixed phosphoramidites to create Ôdegen-erateÕ codons, it is not possible to specify every mix of aminoacids, due to the limitations ... difficult to purify and has a complex doublehydrophobic core (Fig. 4). The authors first sought to directly randomize the structural residues in TIM to estimate the overall tolerance to mutation....
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Tài liệu Báo cáo khoa học: Computational approaches to understand a-conotoxin interactions at neuronal nicotinic receptors doc
... and increasing use of computational tools in the fieldof nicotinic receptors has led to the publication of several models of ligand–receptor interactions. These models are allbased on the crystal ... on the interaction ofa-conotoxins with neuronal nicotinic receptors in light of ournew understanding of the receptor structure. Computationaltools are expected to reveal the molecular recognitionmechanisms ... ligand–receptor interaction.The accurate identification of a-conotoxin interactions with the neuronal nAChR using homology modeling anddocking simulations is expected to provide new informationinto...
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Báo cáo khoa học: "SYNTACTIC APPROACHES TO AUTOMATIC BOOK INDEXING" docx
... manually selected) 209 SYNTACTIC APPROACHES TO AUTOMATIC BOOK INDEXING Gerard Salton Department of Computer Science Cornell University Ithaca, NY 14853 ABSTRACT Automatic book indexing systems ... automatic indexing systems using sophisticated term weighting systems to assess the importance of the indexing units. [Salton 1975a, 1975b] By joining the available linguistic procedures with ... available know-how in automatic indexing, satisfactory book indexing sys- tems may be developed. AUTOMATIC PHRASE CONSTRUCTION Book indexing systems differ from standard automatic text indexing...
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Báo cáo khoa học: "Computational Approaches to Sentence Completion" docx
... comple-tion with LSA is to compute the total similarity of apotential answer a with the rest of the words in thesentence S, and to choose the most related option.We define the total similarity as:totsim(a, ... novels, and is identicalin format to the SAT questions. Due to the source ofthis data, we refer to it as the Holmes data. To train models, we have experimented with avariety of data sources. ... set,along with the comparable SAT results. Note thatthe latter are derived from models trained with theLos Angeles Times data, while the Holmes resultsare derived from models trained with 19th-centurynovels....
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Báo cáo khóa học: Genetic approaches to the cellular functions of polyamines in mammals potx
... accumulation during latespermatogenesis appears to be detrimental to the germ cellsand, hence, antizyme 3 apparently functions to limit anyODC expression to the early spermatogenesis. The trans-gene-derived ... forms a ternarycomplex with the transcription factor Smad1 and protea-somal subunit HsN3 that is translocated into nucleus inresponse to bone morphogenetic protein receptor activation[22]. In ... developed to the blastocyst stage, i.e., to more advanced stage thanthose grown in vitro in the presence of DFMO [136], wasin all likelihood attributable to maternal components[139]. Attempts to...
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Báo cáo khoa học: "New Approaches to Parsing Conjunctions Using Prolog" pptx
... the theory to be put into practice, there remain two important questions to be answered :- • I-low to produce surface strings from a set of sentences to be conjoined? • tlow to produce ... enough to describe ,~ll of the l)henomenon in coordi:tation, hut also constrained enough to reject all u.'l- gr;unmatical examples without undue complications. It is difficult to ;tcldeve ... sen- testes. We will show how Lhese processes can be combined to produce a parser and a generator. The device used for comparison with Dahl & McCord scheme is a simplified version of the...
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báo cáo sinh học:" Using nurses to identify HAART eligible patients in the Republic of Mozambique: results of a time series analysis" potx
... appointments with MD/MOs, social workersand other treatment support staff) or scheduled to return to the CD4 nurse for periodic monitoring until deemedHAART-eligible based on clinical and/or laboratoryparameters.The ... limiting non-HAART eligible patient visits to MD/MOs. To calculatethis indicator, we selected all adult patients who had ini-tial visits with an MD/MO within 30 days of enrollmentat the HIV clinic, ... mmicek@u.washington.edu; Kenneth H Gimbel-Sherr - ksherr@u.washington.edu; Thomas Koepsell - koepsell@u.washington.edu; James P Hughes - jphughes@u.washington.edu; Katherine K Thomas - kkthomas@u.washington.edu;...
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