Báo cáo y học: "Tumor necrosis factor alpha-dependent aggrecan cleavage and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitro" pptx
Báo cáo khoa học: Tumor necrosis factor-a converting enzyme is processed by proprotein-convertases to its mature form which is degraded upon phorbol ester stimulation pptx
... Tumor necrosis factor-a converting enzyme is processed by proprotein-convertases to its mature form which is degraded upon phorbol ester stimulation Kristina Endres, Andreas ... mature TACEwas inhibited by blocking endocytosis [39] it is possible thatthe effect of phorbol esters on TACE maturation dependson vesicle formation and endocytosis.PMA is known to bind to ... arrows mark the immature enzyme forms and black arrows the mature forms. (B) Quantitativeanalysis of mature TACE degradation by Western blot. The ratio of mature TACE to immature TACE was determined...
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Báo cáo y học: "β Treatment with recombinant interferon-β reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis" ppt
... DahaMR, Kluin PM, Meinders AE, Tak PP: Increased expression of IL-15 in the synovium of patients with rheumatoid arthritis compared with patients with Yersinia-induced arthritis and osteoarthritis. ... protein for the treatment of rheumatoid arthritis (RA). Collagen-induced arthritis was induced in DBA/1 mice.At the first clinical sign of disease, mice were given dailyinjections of recombinant ... treatment. *Statistically significant difference. SEM, standard error of the mean.Figure 2Representative histologic staining (hematoxylin and eosin; ì100) of the ankle joints in mice with collagen-induced arthritis...
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Báo cáo y học: "Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte" pptx
... articleTumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyteAaron R Klooster and Suzanne M BernierCIHR Group in Skeletal Development and ... induced by epidermal growth factor (EGF)Tumor necrosis factor alpha (TNF-α) enhances elongated cell morphology induced by epidermal growth factor (EGF). Confluent monolayers of chondrocytes were ... morphology induced by the combination of tumor necrosis factor alpha (TNF-α) + epidermal growth factor (EGF) are partially reduced by inhibition of MEK1/2Changes in cell morphology induced by the...
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Báo cáo y học: "α Tumor necrosis factor-α blockade in ankylosing spondylitis: a potent but expensive anti-inflammatory treatment or true disease modification" pps
... placebo-controlled trial [2] and afterwardsCommentary Tumor necrosis factor-αα blockade in ankylosing spondylitis: a potent but expensive anti-inflammatory treatment or true disease modification?Filip Van den ... colleagues seemto indicate that at least for the vast majority of ankylosing spondylitis patients treatment with infliximab can not be withdrawn,if one wants to control disease activity in a continuous ... 121AS = ankylosing spondylitis; SpA = spondyloarthropathies; TNF = tumor necrosis factor.Available online http://arthritis-research.com/contents/7/3/121AbstractBlocking tumor necrosis factor-α...
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Báo cáo y học: "Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes" ppt
... anti-inflammatory properties are used in human ther-apy, regulate in vitro CD36 expression. Aspirin increases CD36 expression in lines of human THP1 macrophages [23],dexamethasone induces CD36 expression ... TNFα and adalimumab, a human anti-TNFα monoclonal antibody widely used in human pathology, in CD36 expression in human monocytes. Human monocytes were prepared by adherence from whole-bloodbuffy-coat ... signaling via NADPHoxidase activation. CD36 expression on human monocytes isinhibited by TNFα and independently increased by adalimumab. These data highlight that pro-inflammatory cytokines and...
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Báo cáo y học: "NF-κB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating factor" docx
... articleNF-κB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating ... involved in osteoclastogenesisEffect of dehydroxymethylepoxyquinomicin on serum factors involved in osteoclastogenesis. Effect of dehydroxymethylepoxyquinomicin (DHMEQ) on serum levels of (a) osteoprotegerin ... cell-permeableNF-κB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ), suppresses expression of proinflammatory cytokines and ameliorates mouse arthritis. It remained unclear, however,whether DHMEQ directly affects...
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Báo cáo y học: "Tumor necrosis factor α-induced adipose-related protein expression in experimental arthritis and in rheumatoid arthritis" pptx
... analysis usingsplenocytes of mice with GPI-induced arthritis. Expression ofTNFα-induced adipose-related protein (TIARP) mRNA and protein in spleens, joints and lymph nodes was evaluated, and fluctuation ... splenocytes. In arthritic mice, TIARP mRNAwas expressed mainly in CD11b+ cells in the spleen, and TIARP mRNA level was increased in the joints (accompaniedby joint swelling), especially in hyperplastic ... days 7 and 8, peaked in severity on day 14, and then gradually subsided. High expression levels of TIARP mRNA and proteins were detected in splenocytes on day 7 (the onset of arthritis) . In...
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Báo cáo y học: "Tumor necrosis factor alpha-dependent aggrecan cleavage and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitro" pptx
... and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitroHenning Voigt, Angelika K Lemke, Rolf Mentlein, Michael Schünke and Bodo ... aggre-canase activity might be involved in the early TNFα -mediated aggrecanolysis in the meniscus. Inhibition of aggrecanase activity or TNFα -activity might therefore help to prevent menis-cal destruction. ... tissues can be mediated by both the production of NO and the involvement of matrix-degrading enzymes. We there-fore studied the influence of the NO-synthetase inhibitor L-NMMA on meniscal tissue....
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Báo cáo y học: "Tumor necrosis factor-a enhances hyperbaric oxygen-induced visfatin expression via JNK pathway in human coronary arterial endothelial cells" ppt
... Open AccessTumor necrosis factor-a enhances hyperbaric oxygen-induced visfatin expression via JNK pathway in human coronary arterial endothelial cellsBao-Wei Wang1,2, Chiu-Mei Lin3, Gong-Jhe ... 14 human CAECs. Since JNK kinase inhibitor reduced the visfatin protein expression most significantly. We thenfocused on the JNK kinase pathway on the visfatin protein expression induced by HBO. ... necrosis factor-a enhances hyperbaric oxygen-induced visfatin expression via JNK pathway in human coronary arterial endothelial cells. Journal of Biomedical Science2011 18:27.Submit your next manuscript...
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Báo cáo y học: " Isolated radial head dislocation, a rare and easily missed injury in the presence of major distracting injuries: a case report" ppsx
... report Isolated radial head dislocation, a rare and easily missed injury in the presence of major distracting injuries: a case reportUlfin Rethnam*, Rajam SU Yesupalan and Salah S BastawrousAddress: ... of the radial head in an adult. J Orthop Trauma 1995,9(5):441-4.5. Yasuwaki Y, Itagane H, Nagata Y, Nishimoto S, Nakano A, Tanaka S: Isolated lateral traumatic dislocation of the radial head ... of the radial head. The reduction was achieved in supination and immobilisation of the elbow in flexion and supinationgave a favourable final outcome. In the presence of major distracting injuries...
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Báo cáo y học: " Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis" ppt
... of these cells.Density of neutrophils in synovial tissues of patients with OA and RA The presence of HNP1-3 prompted us to study the den-sity of elastase-positive neutrophils in synovial tissues ... defensins from synovial tissue/ cells and density of synovial neutrophils. (a) Levels of human neutrophil pep-tides 1-3 (HNP1-3) in superfusate of synovial tissue of two patients with rheumatoid ... 3d). The relatively low density of neutrophils is due to the factthat neutrophils were present mainly in the lining and adjacent sublining area but not in deeper layers of the synovial tissue, ...
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Báo cáo y học: "Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macrophages by an NF-B-dependent pathwa" pptx
... therefore,investigated this proposal and the macrophage signaling pa thways underlying it.Methods: Caspase-3 activity, annexin-V binding/7-aminoactinomycin D (7-AAD) exclusion and cell-cycle analysiswere ... and assayed for caspase-3 activity asdescribed previously [20].Flow cytometry analysisApoptotic cells were quantitated by staining wit hannexin V-PE and 7-AAD, as specified by the manufac-turer ... promotes degradation of IkBa and resynthesis over 60 minutes. IBa and b-actinprotein levels were assessed by Western blot analysis and quantified by densitometry (lower panel). Densitometry...
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Báo cáo y học: " α Tumor necrosis factor-α and muscle wasting: a cellular perspective" docx
... pathway activates Jun-N-terminalkinases and the transcription factor AP-1. The thirdpathway activates NF-κB, a primary mediator of tran-scriptional control and a major candidate for catabolicsignaling. ... pathways mediate the cellular response to TNF -α. One pathway stimulatesapoptosis via interaction with the TNF -α- receptorcomplex and the Fas-associated protein with deathdomain. A second pathway ... reactive oxygen species (ROS) production viamitochondrial electron transport. NF-κB appears toincrease activity of the ubiquitin/proteasome pathway,Commentary Tumor necrosis factor- α and muscle...
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Báo cáo y học: "Tumor Necrosis Factor-α +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease" doc
... emphysema, is associated with TNF-α +489G/A gene polymorphism. Keywords: Caucasians, COPD, Gene polymorphism, Susceptibility, Tumor necrosis factor-α IntroductionThe pro-inflammatory cytokine ... 1http://respiratory-research.com/content/3/1/29Kỹỗỹkaycanet al.Research articleTumor Necrosis Factor- +489G/A gene polymorphism is associated with chronic obstructive pulmonary diseaseMehmet Kỹỗỹkaycan1, Michiel Van ... study the putative involvement of TNF-α gene polymorphisms in pathogenesis of COPD was studied by analysis of four TNF-α gene polymorphisms in a Caucasian COPD population.Methods: TNF-α gene polymorphisms...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyencd11b gr 1 lo cells isolated from joints of tumor necrosis factor transgenic mice express high levels of vegf cbáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngbáo cáo y tế học đường cuối nămbáo cáo y tế học đường năm 2012báo cáo y tế học đường trường mầm nonbiểu mẫu báo cáo y tế trường họcbáo cáo y tế học đường trường tiểu họcbáo cáo y tế trường tiểu họcBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDENghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinChuong 2 nhận dạng rui roQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015