... Kizawa H, Kou I, Iida A, Sudo A, Miyamoto Y, Fukuda A, Mabuchi
A, Kotani A, Kawakami A, Yamamoto S, Uchida A, Nakamura K,
Notoya K, Nakamura Y, Ikegawa S: An aspartic acid repeat poly-
morphism ... analysis in disc as was
reported by Kizawa et al. [4] in cartilage. Another shortcoming
is that we were not able to carry out a complete analysis of the
localization of asporin...
... specifically control the PGE
2
synthesis asso-
ciated with inflammation in patients with OA and other
inflammatory diseases.
Conclusion
mPGES-1 was upregulated by proinflammatory cytokines
in OA chondrocytes ... 485 ATG CAG CCT GCT TCT GCA AA
CCT TAC TCC AGA TCT GGC AT
30
COX-1 401 CTT TCT CCA ACG TGA GCT ATT
GTG CAT CAA CAC AGG CGC CTC TTC
32
COX-2 1157 AGA CAG ATC ATA AGC GAG GGC C...
... to mannan (data not shown).
Assessment of MBL pathway activation
MBL pathway activation was assessed by an enzyme-linked
immunosorbent assay technique that measures the complete
MBL pathway activity ... pathway in this assay, an antibody
against C1q is added to the reaction mixture [23]. Functional
activity of the MBL pathway was expressed as percentage of
a standard consisting...
... advanced OA. In contrast to general-
ized arterial calcification of infancy, in which hydroxyapatite
crystals are formed, calcium pyrophosphate dihydrate crystal
deposition is observed in these patients ... hand
OA in a large sample of Caucasian nuclear families. We
focused our attention on a relatively isolated population in
southern Russia, the Chuvashians. They live in...
... thus the recall bias may affect the accuracy of information
gathered. Finally, vitamin D intake was not assessed in our
population.
Despite these limitations, the present findings are not antici-
pated ... she was classified as having finger OA.
Symmetrical OA was defined as a subcategory of OA in at
least two symmetrical pairs of the joints (if two joints of the
hand are af...
... 2005,
310:644-648.
24. Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, Ishikawa S, Fujiwara S,
Watanabe H, Kurashina K, Hatanaka H, Bando M, Ohno S, Ishikawa Y,
Aburatani H, Niki T, Sohara Y, Sugiyama Y, Mano H: ... validation of the
fusion candidate. All validated fusions in this data set
have breakpoints lying at the exon boundary. This
might indicate that, in case of geno...
... Access
ExpressionPlot: a web-based framework for
analysis of RNA-Seq and microarray gene
expression data
Brad A Friedman
1,2,3*
and Tom Maniatis
4
Abstract
RNA-Seq and microarray platforms have ... looking at the distribution of the whole
set, the event_heatmap tool visualizes the individual
levels or fold-change of all the genes in the set as a
heatmap (Figure 6c)....
... National
Academy of Sciences of the United States of America 2004, 101:6062–7.
15. Ihaka R, Gentleman R: R: A Language for Data Analysis and Graphics.
Journal of Computational and Graphical Statistics ... performance against alternative
approaches. In all cases, SpeCond displayed higher sensitivity and a lower false
discovery rate. Importantly, the SpeCond package is not a...
... between hypoalbu-
minemia and CVD is the reflection of inflammation
induced malnutrition. The underlying mechanism be-
hind this includes appetite suppression and increased
catabolism by inflammatory ... hypoalbuminaemia is an independent predictor of CVD in early CKD stages; b) hypoalbu-
minaemia may be used to identify the population at higher risk for CVD.
Key words: Hyp...