Báo cáo y học: "Colony variability under the spotlight in animal models of arthritis" pps
Báo cáo y học: "Colony variability under the spotlight in animal models of arthritis" pps
... distinct colonies of the susceptible mouse strainBALB/c. Although induction of disease by the usualimmunisation regime did not reveal any differences in incidence and severity, the sub-lines of ... of the research was to compare the incidence and severity of PGIAand proteoglycan-induced spondylitis and to determineexpression patterns of a panel of relevant genes in a largenumber of distinct ... that use inbred strains of mice as models for otherhuman diseases, particularly in cases when groups havepublished contradictory data.Competing interests The author declares that they have no...
- 2
- 234
- 0
Báo cáo y học: "Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination" pot
... [13].Alterations in the citrullination of myelin proteins and autoim-mune targeting of citrullinated myelin proteins have beenobserved in MS. Myelin basic protein (MBP) is partially citrull-inated (C8 isoform) ... using myelin and synovial antigen arrays. (a, b) Synovial and (d, e) myelin arrays were produced by printing synovial and myelin peptides and proteins in ordered arrays on the surface of microscope ... and 2). The smearobserved in lanes containing the CIA joint protein lysates wasmost probably due to heavy glycosylation of multiple synovialproteins, and the smearing limited our ability to excise...
- 12
- 364
- 0
Báo cáo y học: " Preliminary data concerning the reliability and psychometric properties of the Greek translation of the 20-item Subjective Well-Being Under Neuroleptic Treatment Scale (SWN-20)" pdf
... in order to assess the well-being of patients receiving antipsychoticmedication independent of the improvement in their psychotic symptoms. The current studyreports on the reliability and the ... treated eitherwith FGAs or SGAs showed that both quality of life andsymptom severity improved over the study period, regard-less of the antipsychotic taken, indicating that the type of antipsychotic ... and SD participated in the gather-ing of the data, interpretation of the results and writing of the manuscript.Acknowledgements The study was based on a research grant by AstraZenca Greece.References1....
- 8
- 412
- 0
Báo cáo y học: "DAS28 best reflects the physician''''s clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment" potx
... givea dose increase of infliximab could happen only at one timepoint. This difference in study design and therapy may explainwhy in the present study the AUC of DAS28 is smaller than in other studies ... remaining disease activity in daily prac-tice (and in clinical trials). The aim of the present analyses wasto evaluate whether the decision to increase the dose could bereflected by using single ... broadspectrum of manifestations that requires an early intensivetherapy in order to avoid joint destruction and physical disabil-ity. In order to measure the effect of therapy in daily practiceand in...
- 9
- 431
- 0
Báo cáo y học: "How safe are the biologicals in treating asthma and rhinitis" doc
... clinical trials.Interleukin-4 and Interleukin-13 InhibitionInterleukin-4 (IL-4) and Interleukin-13 (IL-13) arecytokines that play a role in allergic inflammation byinducing Th2 responses. Interleukin-4Rα ... authorsconcluded that there may be an increased risk of anaphy-laxis in asthmatic patients that may be dependent on the severity of asthma.Another variable and difficulty in interpreting the safety of biologics ... immunotherapy, the oldest biologic agent in current use, has the highest of frequency of the most serious and life-threatening reaction,anaphylaxis. It is also one of the only disease modifying interventions...
- 11
- 459
- 0
Báo cáo y học: "Preliminary evidence for a change in spectral sensitivity of the circadian system at night" potx
... different times of the night. These findings arehypothesized to be the result of a change in the sensitivity of the melanopsin-expressing retinalganglion cells to light during the night.BackgroundIt ... (rPA)was obtained by dividing the pupil area by the iris area.Only the rPA values obtained during the light exposureperiods were analyzed. All of the rPA values for a one-minute recording session ... condi-tions, the differential effects of the two spectra at the twotimes of the night strongly suggest that there is a change in the spectral sensitivity of the retinal phototransductionmechanisms of the...
- 9
- 363
- 0
Báo cáo khoa học: Recent insights into cerebral cavernous malformations: animal models of CCM and the human phenotype pptx
... phenotype. The myocardium proliferates to anormal number of cells, but instead of building intoconcentric layers to form the walls of the heart, the myocardial cells form into a single layer, ... mitogen-activated protein kinas-es (see the accompanying minireview [11] on the bio-chemical interactions of the CCM proteins).Furthering the pursuit of genetic interactions,co-morpholino experiments ... helptranslate the cellular and biochemical insights into a better understanding of disease mechanism. In this minireview, we discuss the contributions of animal models to our growing understanding of the...
- 8
- 416
- 0
Báo cáo y học: "Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis" ppsx
... detection of microbial antigens in the synovial tissuesby immunohistological staining.Conclusions Genetically defined cytokine production in the joint defines the severity of reactive arthritis by ... in the joint defines the severity of ReA by dictating the local clearance of the patho-gen. This interplay can be dramatically altered by heavy metalexposure, which results in suppression of ... reducedviability of C. pneumoniae in the infected cells [31]. In our in vivo model, the rise in NO was concurrent with an increase in chlamydial load in the host, suggesting that the increase in NOwas...
- 10
- 403
- 0
Báo cáo y học: "ITGAV polymorphism and disease susceptibility in a Japanese rheumatoid arthritis population" ppsx
... patients in the Japanese was not observed. Further studies in other ethnicgroups are necessary to draw definite conclusions.Competing interests The authors declare that they have no competing interests.References1. ... Cheresh DA: The role of alphav integrins duringangiogenesis: insights into potential mechanisms of actionand clinical development. J Clin Invest 1999, 103:1227-1230.4. Osorio YFJ, Bukulmez ... detect the effect of the ITGAV gene (> 0.96;number of cases = 1504, number of controls = 449, OR in the original French study [1] = 1.94, frequency of rs3738919-A allele in the controls = 0.078,...
- 2
- 313
- 0
Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtMÔN TRUYỀN THÔNG MARKETING TÍCH HỢP