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Báo cáo y học: "Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis" pdf

Báo cáo y học:

Báo cáo y học: "Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis" pdf

... simply reflect the level of synthesis/release and catabolism of endocannabinoids and entourage compounds in the synovium. The source of the endocannabinoids present in the synovium and synovial fluid ... Representativemicrographs of this grading system are presented in Figure 1.Quantification of inflammatory cytokines in synovial fluid Cytokine profiles in synovial fluid were determined using aBD™ cytometric ... 1. Patients were told to stop taking aspirin and all cytokine inhibitors 10to 14 days prior to surgery.Histology of synovial biopsies and levels of cytokinesHaematoxylin and eosin histology...
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Báo cáo y học: " Characterisation of the immune response to type I collagen in scleroderma" pps

... detected interferon (IFN)-γ staining but no interleukin (IL)-4 staining. Mul-tiplex cytokine assay was used to analyse the cytokine profile of three T-cell line supernatants. (b) An excess of Th1 ... al.Page 6 of 9(page number not for citation purposes)Cell line cytokine profileWe were interested in comparing the Th1 and Th2 cytokinesecretion profile of CI-specific cell lines. Cell lines generatedfrom ... our findings, we also analysed intracellular cytokineproduction by flow cytometry, using fluorochrome-conjugatedantibodies to IFN-γ and IL-4 as representative cytokines of aTh1 and Th2 profile,...
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Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

... member of the Hsp70 family and promotes the folding and assembly of protein byrecognizing unfolded polypeptides and inhibiting intra- and intermolecular aggregation [17]. To investigate the role of ... CRThave been described as being necessary to the folding and oligomeric assembly of various glycoproteins [17].To study the role of CNX and CRT in the folding of newly synthesized TSHR molecules, ... of the main molecular chap-erones present in the endoplasmic reticulum, interact with the TSHR and what effects these interactions might haveon the folding of the receptor. In the first set of...
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Báo cáo y học: "Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes" pps

... RA.Introduction Rheumatoid arthritis (RA) is a chronic inflammatory diseasecharacterized by synovial lining hyperplasia and sublining infil-tration of inflammatory cells [1]. Fibroblast-like synoviocytes(FLSs) ... in rheumatoid arthritis synoviocytesDeepa R Hammaker1, David L Boyle1, Tomoyuki Inoue2 and Gary S Firestein11Division of Rheumatology, Allergy and Immunology, UCSD School of Medicine, ... arthritis synoviocytes. J Clin Invest 1990,86:1790-1798.4. Alvaro-Gracia JM, Zvaifler NJ, Brown CB, Kaushansky K, FiresteinGS: Cytokines in chronic inflammatory arthritis. VI. Analysis of the synovial...
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Báo cáo y học: "Reliability of the TekScan MatScan® system for the measurement of plantar forces and pressures during barefoot level walking in healthy adults" potx

... study was to deter-mine the reliability of the TekScan MatScan® system in assessing plantar forces and pressures during level bare-foot walking using a test-retest analysis of thirty healthyasymptomatic ... Zammit G, Landorf K, Handley C, Elzarka A, Deluca J: Efficacy of intra-articular hyaluronan (Synvisc(R)) for the treatment of osteoarthritis affecting the first metatarsophalangeal joint of the foot ... practice. The purpose of this study was to investigate the reliability of the TekScan MatScan® system in assessing plantar forces and pressures during barefoot level walking.Methods: Thirty participants...
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Báo cáo y học: "Use of the measure your medical outcome profile (MYMOP2) and W-BQ12 (Well-Being) outcomes measures to evaluate chiropractic treatment: an observational study"

... correlating with the findings of the SF-36 [1].Based on this and the observational findings of thisstudy, the MYMOP2 has potential as a clinically usefultool to assess chiropractic care in terms of ... objective was to investigate the validity of the MyMOP2 instrument to detect a change in well-being of patients attending the RMIT chiroprac-tic teaching clinic. The mean baseline MYMOP2 profile score ... deliveredby student chiropractors in a clinical teaching facility. The W-BQ12 was also used as a tool to assess the validity of the well being component of the MyMOP2 against the validated W-BQ12 instrument...
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Báo cáo y học: "Impact of the Kenya post-election crisis on clinic attendance and medication adherence for HIV-infected children in western Kenya"

... hugerisks and acted with great bravery to return to the clinic and to obtain their medication refills.▪ Patients really surprised us. They walked distances, theyran away, they tried again, they came ... University School of Medi-cine and Moi Teaching and Referral Hospital (Eldoret,Kenya) and the Institutional Review Board of the IndianaUniversity School of Medicine (Indianapolis, Indiana).Informed ... complementedthese analyses with qualitative key informant interviews of selected healthcare providers who were working within the AMPATH clinical care system during the time of the post-election...
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Báo cáo y học: "Evaluation of the Prevalence of Concomitant Idiopathic Cyclic Edema and Cellulit"

... of idiopathic cyclic edema was based on a clinical history and fluid retention throughout the day, in particular difficulty in removing rings on waking in the morning which improves later in ... The lack of specific clinical and laboratory studies hinders research on cyclic edema and the dissemination of information on this disease. The fact that it is idiopathic is another limiting ... later in the day. All patients with cyclic edema were treated with 75 mg aminaphtone three times daily. Statistical analysis con-sidered the frequency of edema. Of the 82 women evaluated with...
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Báo cáo y học:

Báo cáo y học: "Enhancement of the Click Chemistry for the Inverse Diels Alder Technology by Functionalization of Amide-Based Monomers"

... the cor-responding tetrazine 6, which in turn reacts with a mixture of the dansyl derivative and the N-ethyl-diisoproylamine and the dansyl sulfamidoethylamine to the tetrazine product 7 linked ... glycine’s N-terminus, as originally described by Nielsen in the protocols for the synthesis of the peptide nucleic acid (PNA) backbone [29, 30]. We synthesized and investigated ligations of ... cell- and tissue specific therapeutic approaches. They are also ideal as diagnostic tools in the increas-ing fields of the patient-specific therapy and in imag-ing of metabolic processes at the...
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Báo cáo y học: " Efficacy of the Valsalva Maneuver on Needle Projection Pain and Hemodynamic Responses During Spinal Puncture"

... obtund pain of needle insertion including infiltration analgesia and EMLA patch. Local anesthetics themselves may pro-duce pain on injection and many anesthetists are un-sure that infiltration ... venous canulation could decrease the incidence and severity of pain associated with venipuncture in adult patients. 7 In another study by Gupta et al the efficacy of ... spinal puncture and first and third minutes after that were also recorded. Statistical analysis In a pilot study of 20 patients having spinal an-esthesia by 25-guage Quincke needle, 90% of...
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