... position 42 of the vacidin A side chain,Fig. 1) are available for at least five polyene macrolides thatbelong to a group of polyenes specifically glycosylated bymycosamine, a hexose of theD-series. ... antifungal properties. Polyene macro-lides are of an authentic clinical value for efficient therapiesagainst animals, and human infectious diseases caused bypathogenic fungi. In particular, nystatin ... ChimiePhysique & Electronique de Lyon, Villeurbanne, France Glycosylated polyene macrolide antibiotics, as nystatins andamphotericins, are amphiphilic structures known to exert antifungal activity...