... implications.Introduction Rheumatoid arthritis (RA) is a chronic disabling inflammatorydisease with increased risk of premature death, mainly due tocoronary vascular disease [1], but modern therapeutic strate-gies in early ... 21:885-906.2. Askling J, Dixon W: The safety of anti-tumour necrosis factortherapy in rheumatoid arthritis. Curr Opin Rheumatol 2008,20:138-144.3. Cush JJ: Early rheumatoid arthritis is there a window ... decreased 3 years after diagnosis and insti-tuted DMARD therapy – but rather, on the contrary, hadincreased. We think this observation is interesting, but it needsfurther scrutiny in future...