Báo cáo y học: "Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-β/bone morphogenic protein signalling" pot
Báo cáo y học: "Differential gene expression in HIV/SIV-associated and spontaneous lymphomas"
... a-myb and capn4 genes in non-HIV-associated lymphomas and B-lymphocytes (Fig. 2a). The pub gene was slightly transcribed in B-lymphocytes and not transcribed in all non-HIV-associated lymphomas ... lymphomagenesis in human and monkey. Table 4. Selected human HIV-associated lymphomas h1 and h2 genes overexpressed in SIV-associated monkey lymphomas in comparison with monkey B lymphocytes ... dehydrogenase subunit 4 gene, IL5 – the interleukin 5 gene, λIg – the λ-chain of immunoglobulin gene, γIg – the γ-chain of immunoglobulin gene, IFN-ind – the interferone-inducible gene...
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Báo cáo y học: "Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats" potx
... respectively).DiscussionBy using microarray and real-time PCR, we investigateddifferential gene expression in the draining inguinal lymphnodes between the arthritis- susceptible DA and arthritis- resistant E3 rats ... analyzed individually.Flow cytometry analysisThe cell type composition and level of protein expression for some genes in the inguinal lymph nodes were analyzedby flow cytometry. Single cell ... cells in lymph nodes in DA and E3 naïve rats and rats 8 days after pristane injectionTotal cell number (millions)Difference between Difference between Cell type DA day 0* E3 day 0* DA and E3...
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Báo cáo y học: "Differential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patients" pptx
... 6Research articleDifferential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patientsLe-Hoa ... pro-duced by the various bone marrow and bone cell types in the bone microenvironment [42,43]. The role of these growth factors suggests their involvement in the preservation of the bone matrix. The ... is hypothesised to be due to increasedOB biosynthetic activity [18]. The lack of differential gene expression of these anabolic growth factors in our study ismost likely due to the gene expression...
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Báo cáo y học: "Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-β/bone morphogenic protein signalling" pot
... articleMicroarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-β /bone morphogenic protein signallingBlair Hopwood1,2, Anna Tsykin3, ... differentiallyexpressed genes in OA bone. Altered expression of WNT and TGF-β/BMP signalling pathway component and target genes in OA bone A significant number of the top-ranking differentially expressedgenes ... and consistency between the microarray and PCR detection of expression ratio differences for each of thegenes analyzed, suggesting that the majority of the genesidentified by the microarray...
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Báo cáo y học: " Microarray-based genomic surveying of gene polymorphisms in Chlamydia trachomatis" ppsx
... genomic surveying of gene polymorphisms in Chlamydia trachomatis<p>By comparing two fully sequenced genomes of <it> ;Chlamydia trachomatis </it>using competitive hybridization ... nothighly ranked in any of the other strains, the results indicatedthat the trp operon was present in the remainder of thestrains. The CT868 gene region of strain L1/440 was interest-ing because of ... evolution: a billion years andcounting. In Chlamydial Infections, Proceedings of the Tenth InternationalSymposium on Human Chlamydial Infections:16-21 June 2002. Antalya,Turkey Edited by: Schacter...
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Báo cáo y học: "Host gene expression profiling in influenza A virus-infected lung epithelial (A549) cells: a comparative analysis between highly pathogenic and modified H5N1 viruses" ppt
... this article as: Chakrabarti et al.: Host gene expression profiling in influenza A virus-infected lung epithelial (A5 49) cells: a comparative analysis between highly pathogenic and modified H5N1 ... was done using gene annotation files and raw data were extracted into MS EXCEL.Data Analysis Data was analyzed using GENOWIZ Microarray and Pathway analysis tool (Ocimum Biosolutions, Hyderabad,India). ... human lung carcinoma cells (A5 49) at early and late stages of infectionwith highly pathogenic avian Influenza A (H5N1) virus and compared it with a reverse genetics modified recombinant A (H5N1) ...
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Báo cáo y học: " Angiogenesis gene expression in murine endothelial cells during post-pneumonectomy lung growth" pptx
... Open Access Angiogenesis gene expression in murine endothelial cells during post-pneumonectomy lung growthMiao Lin1, Kenji Chamoto1, Barry C Gibney1, Grace S Lee1, Dinee Collings-Simpson1, ... phe-notypically uniform cell type (endothelial cells) andFigure 2 Cell cycle profiling of post-pneumonectomy lung CD31+ endothelial cells obtained by enzymatic digestion and analyzedusing flow cytometry ... was obtained using cell cycle flow cytometry ofCD31+ endothelial cells (Figure 2). An early increase in S-phase cells was noted on Day 3 after pneumonectomy.By Day 6 after pneumonectomy, 10%...
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Báo cáo y học: "Smad gene expression in pulmonary fibroblasts: indications for defective ECM repair in COPD" ppsx
... downregulation of decorin gene expression in COPD patients, at least partially via theSmad pathway. Our findings may explain why only a sub-set of smokers demonstrates an excess parenchymal ECM destruction ... inadequate in a subset of smokers, leading togradually increasing parenchymal ECM destruction andemphysematous changes [9]. We addressed three ques-tions to obtain more insight in the underlying ... inducing ubiquination of their receptors.Additionally, Smad7 can induce TGFβ-production byfibroblasts upon activation by pro-inflammatorycytokines like TNF and IFN-gamma, thereby enablingautocrine...
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Báo cáo y học: " Global gene expression patterns in the post-pneumonectomy lung of adult mice" ppt
... 1). Second, global gene expression patterns in the lung were analyzed independ-ently at each of the four time points following pneumon-ectomy (6 hours, 1 day, 3 day and 7 day). In this time-dependent ... purposes)Illustrations of the top gene networks at the 7 day time point of the time-dependent microarray analysisFigure 5Illustrations of the top gene networks at the 7 day time point of the time-dependent ... anti-inflammatory transcriptomicpattern observed during lung regeneration in this study,another recent study describes up-regulation of selectinflammatory cytokines (Hmgb1 and INF -y) during...
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Báo cáo y học: "The gene expression profile of preclinical autoimmune arthritis and its modulation by a tolerogenic disease-protective antigenic challeng" ppt
... Alleva D, Acosta HM, Martinez C, Ortega A, Lopez A, Araiza-Casillas R, Zlotnik A: Gene array analysis comparison between rat collagen-induced arthritis and human rheumatoid arthritis. Scandinavian ... acceptance. Copyedited and fully formatted PDF and full text (HTML) versions will be made available soon.The gene expression profile of preclinical autoimmune arthritis and its modulation by ... Pk phase of AA (Figure 1 and 2). This was evident by both the number and the level of expression of DEG. Rats at Inc phase had no overt signs of clinical arthritis (preclinical AA). A comparison...
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Báo cáo y học: " Tax gene expression and cell cycling but not cell death are selected during HTLV-1 infection in vivo" potx
... Zane et al.: Tax gene expression and cell cycling but not cell death are selected during HTLV-1 infection in vivo. Retrovirology2010 7:17.Submit your next manuscript to BioMed Central and take ... 101520253035 HTLV-1 Phenotype - + - +-+- + CD4+ CD8+CD4+ CD8+ Infection oviv nI ortiv nI** % Cells Figure 4 Cell cycling but not cell death is sel ected during HTLV- 1infection in vivo.CD4+ and ... and cell cycling but not cell death are selected during HTLV-1 infection in vivoLinda Zane1, David Sibon1,2,7, Lionel Jeannin1, Marc Zandecki3, Marie-Hélène Delfau-Larue4, Antoine...
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Báo cáo y học: "Early gene expression changes with rush immunotherapy" ppt
... study to evaluate gene expression changes inpatients undergoing IT. The goal of the study was to iden-tify a unique gene profile in RIT patients c ompared tohealthy controls and those with ... allergic patients to healthycontrols, the authors found only modest differences inthe gene expressions of the 32 genes. More recently,Zhang et al. analyzed gene expression of chemokines andtheir ... study include thatthe analysis was perform ed at only 2 timepoints as wellas the microarray dataset analyzed only 4100 genes.TGF-b was the only transcript that the authors identi-fied with...
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Báo cáo y học: "Common gene expression strategies revealed by genome-wide analysis in yeast" ppt
... comprehensive analysis of six variables characterizing gene expression in yeast, including transcription and translation, mRNA and protein amounts, reveals a general tendency for levels of mRNA and protein ... half-lives in the budding yeast proteome. Proc NatlAcad Sci USA 2006, 103:13004-13009.10. MacKay VL, Li X, Flory MR, Turcott E, Law GL: Gene expression analyzed by high-resolution state array analysis ... mainly by coordinating their synthesisrates, either if they correspond to abundant proteins, such asthe ones belonging to macromolecular complexes, or toscarce ones, such as those involved in...
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Báo cáo y học: "Genome-wide expression profiling and bioinformatics analysis of diurnally regulated genes in the mouse prefrontal cortex" pps
... Biology 2007, 8:R247Open Access2007Yanget al.Volume 8, Issue 11, Article R247ResearchGenome-wide expression profiling and bioinformatics analysis of diurnally regulated genes in the mouse prefrontal ... genes in the mouse genomeFigure 1A karyotype map showing the chromosome positions and frequencies of diurnally regulated genes in the mouse genome. Although these genes are scattered around the ... are regulated by TFs in other clusters (in Figure 4, many cells in the rows for TFBS2 and TFBS7 arered). Therefore, the diurnal expression of many genes in thesethree clusters may be due to the...
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Báo cáo y học: "Differential gene expression in anatomical compartments of the human eye" pptx
... exception being an intermingling of the ciliary body andiris specimens (Figure 1a). The lack of a clear distinctionbetween the expression patterns of the ciliary body and irismay be due to both their ... encodedproteins that help maintain the shape, transparency, or integ-rity of the cornea, which serves as the primary refractive ele-ment in the eye. Some of the genes encoded proteinsspecifically expressed ... obtained post-mortem. The expression of the inflammatory genes could therefore reflect,at least in part, changes in the eye that occur after death.Future studies examining gene expression in...
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