... amyloid and advanced glycation end products (AGEs)[15]. AGEs are the products of nonenzymatic glycation and oxidation of proteins that form with aging, diabetes and renalfailure, and at sites of inflammation ... Goodson and colleaguesrecently demonstrated 10% mortality, predominantly owing toCV events, within 10 years of onset of inflammatory polyarthri-tis [27]. In a large study of CV mortality in RA ... and RAGEGly82→Ser polymorphism in 232 patients with RA attending atertiary referral hospital. CV events, the duration and severity of RA, and risk factors for CV disease were determined usingpatient...