... providing an additional contact with
the SH2 domain of SOCS-3 involving R94. A conforma-
tional change induced by the phosphorylation of tyrosine
Y4 31 may also contribute to the increase in binding affinity
compared ... subtracted nonspecific
binding. Determination of the dissociation constant was
carried out by Scatchard analysis [22].
Peptide precipitation assay and imm...
... 2002
A single charged surface residue modifies the activity of ikitoxin,
a beta-type Na
+
channel toxin from
Parabuthus transvaalicus
A. Bora Inceoglu
1,
*, Yuki Hayashida
2
, Jozsef Lango
3
, Andrew ... Laboratory, University of California, Davis, CA, USA
We previously purified and characterized a peptide toxin,
birtoxin, from the South African sco...
...
coronary angiography in the study by Weiss et al.
showed a higher sensitivity and specificity for the
detection of coronary stenosis by 3DMP than by
12-lead ECG [18].
One lim
itation of the ...
systems. In the case of the heart, analysis is performed
on the signals emitted by the heart, such as the surface
resting electrical signal recorded by an ECG....
... nonobstructive coronary artery disease.
Heart Dis. 2002; 4: 2-12.
22. Grube E, Bootsveld A, Yuecel S, et al. Computerized two-lead
resting ECG analysis for the detection of coronary artery
stenosis. ...
Computerized two-lead resting ECG analysis for the detection of coronary
artery stenosis after coronary revascularization
Eberhard Gru...
...
Monoclonal Antibodies against Nucleophosmin Mutants: Potentials for the
Detection of Acute Myeloid Leukemia
Shi Tan
1
, Ling Zhang
1
, Xiao-Ming Zhong
1
, Zai-Lin Yang
2
, Liu-Yang Zhao
1
, Yu-Jie ...
value of their detection by immunocytochemistry. Blood. 2002;
99: 409-26.
17. Falini B, Mecucci C, Tiacci E, et al. Cytoplasmic nucleophosmin
in acute myelo...
... sIL-1R, increasing the
binding affinity of IL-1α and IL-1β to type II sIL-1R by
approximately 100-fold, while leaving unaltered the low
binding affinity of IL-1Ra to type II sIL-1R, thus enhancing
inhibition ... are
broader and include activating or increasing the level of
factors able to inhibit proinflammatory cytokines or other
catabolic factors.
Interleukin-1
β
For s...
... responsible for most of the
experiments, data analysis and drafting of the manuscript.
HEH helped conceive of the study and shared responsibility
for study design coordination and drafting of the manuscript.
ES ... HMGB1
expression has been demonstrated in human and experimental
synovitis. The aim of the present study was to elucidate the
temporal and spatial expr...
... response.
Identifying the signalling pathways that are involved in
inducing the observed alterations in MMP expression may
contribute to our understanding of the initiation of kidney
damage in lupus nephritis. ... Candidate
mediators of such changes include enzymes and signalling
substances involved in maintaining the delicate balance
between synthesis and breakdow...
... genes, and the total has steadily
grown since then.
Currently, the average number of genes listed in the
human gene catalogs appears to be somewhere around
22,500, with an uncertainty of around ... uncertainty surrounding their
numbers. In recent years, as a result of the dramatic
breakthroughs in our understanding of RNA interference
[7] and miRNAs [8], the...
... dermatophyte genomes encode the basic meta-
bolic machinery for glycolysis, tricarboxylic acid cycle,
glyoxylate cycle, pentose phosphate shunt, and synthesis
of all 20 standard a mino acids and the ... Comparative and functional
genomics provide insights into the pathogenicity of dermatophytic
fungi. Genome Biology 2011 12:R7.
Submit your next manuscript to BioM...
... problem among women of
reproductive age. The behavior and other characteristics of
the male partners in this study were important predictors
for HIV in women. Therefore, involvement of men in HIV
prevention ... regarding the
male partner& apos;s behavior characteristics was reported by the
women. The accuracy may be low due to lack of openness
regardin...
... cells
Since induction of cytolytic effector cells is pivotal in
ensuring the success of tumor vaccines, we investigated
relative efficacy of phytols and known adjuvants in their
ability to augment ... formulation: 1. assessment
of safety and efficacy during stimulation of humoral and
cell-mediated immune responses
So-Yon Lim
1,2
, Matt Meyer
1,3
, R...
... helped in physiotherapy and functional recovery of the hand in a month.
Conclusion: A continuous blockade of the brachial plexus with a low concentration of bupivacaine and fentanyl helps
to alleviate ... Glove Syndrome after intravenous
administration of phenytoin. She was managed conservatively by limb elevation, physiotherapy and oral antibiotics. A
20G i...
... Montero-Marín et al.: Sociodemographic and
occupational risk factors associated with the development of different
burnout types: the cross-sectional University of Zaragoza study. BMC
Psychiatry 2011 11:49.
Submit ... 5.50).
Burnout type, sociodemographic and occupational risk
factors
Table 3 shows the raw and adjusted ORs for the “fre-
net...
... will be at least 18 years old with a primary
complaint of thoracic pain (Figure 1: Mannequin defining
the area of thoracic pain) and with no contraindications
to manual therapy or Graston Technique.
Upon ... trial performed assessing the effectiveness of
spinal manipulative therapy on thoracic spinal pain [1].
Spinal manipulative therapy (SMT) was compared to...