Báo cáo y học: "Relationship between physical activity and stiff or painful joints in mid-aged women and older women: a 3-year prospective study" pot

... Anti-CCP antibodies may also be related increased oxidative activity in RA patients. Anti-CCP antibodies are directed against antigens containing the nonstandard amino acid citrulline, for example, ... TNF-alpha inhibitors act as a regulator against pentosidine formation, oxidative DNA damage, and lipid peroxidation and is associated with a decrease in serum levels of oxidative stress markers, and ... peroxide (H2O2), and hydroxyl rad-ical (OHS), with the potential to initiate cellular damage in joint tissues especially in RA. They are formed by phagocyte activation during inflammation. The...

... or cause prompted you to seek help in our outpatient clinic? (Mark as many items as apply) anal bleeding - in toilet paper, faeces or lavatory anal itch anal pain or discomfort anal burning ... for continuous variables such as age. Frequencies and percentages were calculated for categorical data such as the male to female ratio, history of symptoms, and anal lesions. Bivariate analyses ... discomfort anal burning (baking) anal soreness anal lump faecal soiling anal weeping anal mucous anal incontinence dubious abdominal pain constipation diarrhoea faecal occult blood...

... ofalmost all naturally occurring osmolytes. We reporthere that protein stability and activity are not largelycoupled in the presence of osmolytes. However, proteinstability and activity have ... yield and activity of human phenylalanine hydroxylase mutantenzymes produced in a prokaryotic expression system.Mol Genet Metab 73, 173–178.9 Tanaka M, Machida Y & Nukina N (2005) A noveltherapeutic ... l-lysine, l-serine, b-alanine, taurine, sarcosine,dimethylglycine, glycine betaine, trimethylamine N-oxide, and cytidine 2¢-3¢ cyclic monophosphate were also obtainedfrom Sigma. These and other...

... have a typical T-helper 2(Th2) cytokine inflammatory pattern as measured in rhino-sinusal lavage. Nonatopic or intrinsicasthmatic patients have an inflammatory patternsimilar to that of atopic ... MucosaSegmental bronchial allergen challenge in nonasth-matic allergic rhinitis patients leads to a decrease in nasal peak inspiratory flow and a concomitantincrease in nasal symptomatology.31It alsoincreases ... and mediator- or inflammatory-cell circulation. Inflam-matory mediators can reach the lower airwayfrom the upper airway through the airway pas-sages. They might also be able to reach the lowerairway...

... Tomokazu Sawada and Akira NaganoDepartment of Orthopaedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, JapanCorresponding author: Masaaki Takahashi (e-mail: taka1m@hama-med.ac.jp)Received: ... immunoassay kits (Fuji ChemicalIndustries, Toyama, Japan) [9]. The intra-assay and interassay variations in MMP-3, MMP-9 and TIMP-1 wereless than 8.9%.Statistical analysisThe statistical significance ... pyridinoline were corrected by urinarycreatinine. The intra-assay and interassay coefficients ofvariance were 6.4% and 5.9%, respectively.Serum YKL-40Serum YKL-40 was measured with an enzyme-linkedimmunosorbent...

... both internal systems and external data sources. The most important external datasource is state health department data. Validation of registrydata against health department recorded data involves ... authors would espe-cially like to thank data manager Lisa Ingerson and statistician Nicole Pratt from the Australian Orthopaedic Association National Joint Replacement Registry, and Ms Georgina ... diseases related toaging and obesity, such as OA, will therefore probablybecome more prevalent and will in turn increase the demandfor definitive therapies, such as joint replacement surgery.Obesity...

... (dsDNA), (b) nucleosomes and α-actinin and (c) dsDNA and α-actinin. Absorbance ratios (ARs) for each assay are plotted against each other. The Pearson correlation coefficient is given for each associ-ation ... Com-mittee.Renal outcome measuresFor each patient at each time point, urine was tested for pro-tein/creatinine ratio (PCR), and serum was tested for albumin and creatinine in the routine clinical laboratory. ... immunosorbent assay testsODs from all of the assays were converted to absorbanceratios (ARs) to standardise the data and minimise interassayvariation. The mean OD for each sample was calculated...

... 3120 antiretroviral treatment (ART) and pre-ART cards (Yirgalem); 2180 ART and pre ART cards (Arba-Minch); and more than 20 000 non-ART, ART and pre-ART cards (Hossana). The total number of cases ... collection. EL analysed and interpreted thedata and developed the manuscript. Both authors read and approved the final manuscript.AcknowledgementsWe thank Hawassa University Research and Extension ... haemoglobin, hematocrit and platelets in such analyses and also separate analysis for pregnant women, which we considered as the limitations of thismanuscript.Competing interestsThe authors...

... study and analyzed data. SW managed thelaboratory and participated in the analysis and discussion of the results. Allauthors read and approved the manuscript.Competing interestsThe authors ... of saliva wasdispensed into each well and left for 1.5 h. After anotherwashing, primary antibody (35514; Abcam, USA and FU47500254; Funakoshi, Japan) was added to the plates and incubated for ... the saliva was stored at -20°Cuntil use.Salivary hormone assayThesalivasampleswerecentrifugedat3,000rpmfor10 min to remove all mucin. A standard fluorescentimmunoassay was used to a ssess...