... tissueplasminogen activator and factor XIa [69–71,74,77–91]. The GAG binding site in protein C inhibitorappears to be localized not to the D-helix as in AT and HC-II, but to the H-helix region, with possiblecontributions ... Research Centres for Vaccine Technology and Oral Health Sciences,Monash University, Clayton, Victoria, Australia2 The Victorian Bioinformatics Consortium, Monash University, Clayton, Victoria, Australia3 ... translo-cated from the top to the bottom of the inhibitor [6].In the process, the structure of the protease appears to be deformed by being ‘crushed’ against the bottom ofthe inhibitor [7]. In particular,...