Báo cáo y học: "Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients" potx

Báo cáo y học: "Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain"

Báo cáo y học: "Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain"

... significantly shorter in the CCI rats compared with sham controls. Mechanical allodynia and thermal hyperalgesia in- duced by CCI was attenuated by intrathecal adminis- tration with TLR4 -siRNA (p<0.05, ... Conclusions/Significance: These findings suggest that suppression of TLR4 mediated by intrathecally administered siRNA may be a new strategy for the treatment of neuro...
Ngày tải lên : 25/10/2012, 11:48
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Báo cáo y học: "Association between antipsychotics and weight gain among psychiatric outpatients in Pakistan: a retrospective cohort study" ppsx

Báo cáo y học: "Association between antipsychotics and weight gain among psychiatric outpatients in Pakistan: a retrospective cohort study" ppsx

... and weight gain among psychiatric outpatients in Pakistan: a retrospective cohort study Syed Ahmer* 1 , Rashid AM Khan 1 and Saleem Perwaiz Iqbal 2 Address: 1 Department of Psychiatry, Aga ... Aga Khan University, Karachi, Pakistan and 2 Department of Paediatrics & Child Health, Aga Khan University, Karachi, Pakistan Email: Syed Ahmer* - syed.ahmer@aku.edu; R...
Ngày tải lên : 08/08/2014, 23:20
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Báo cáo y học: "Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab therapy" ppt

Báo cáo y học: "Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab therapy" ppt

... not for citation purposes) Vol 10 No 6 Research article Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab ... enzyme immunoassay; ELISA: enzyme-linked immunosorb- ent assay; MCV: mutated citrullinated vimentin; PTPN22: protein tyrosine phosphatase nonreceptor type 22...
Ngày tải lên : 09/08/2014, 01:22
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Báo cáo y học: "New insights into integrin signalling: implications for rheumatoid arthritis synovial fibroblasts" pptx

Báo cáo y học: "New insights into integrin signalling: implications for rheumatoid arthritis synovial fibroblasts" pptx

... transfer to synoviocytes and osteoclasts. J Clin Invest 1999, 104:137-146. 14. Pap T, Franz JK, Hummel KM, Jeisy E, Gay RE, Gay S: Activation of synovial fibroblasts in rheumatoid arthritis: lack ... cultured rheumatoid synoviocytes. J Rheumatol 1995, 22:817-828. 12. Morel JC, Park CC, Zhu K, Kumar P, Ruth JH, Koch AE: Signal transduction pathways involved in rheumatoid arthritis s...
Ngày tải lên : 09/08/2014, 01:22
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Báo cáo y học: "Improved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation model" potx

Báo cáo y học: "Improved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation model" potx

... 5 Research article Improved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation model Jarno van de Breevaart Bravenboer 1 , Caroline D In der Maur 2 , ... constructs. Discussion In the present study we found an improvement in histologi- cal and biomechanical integration of articular cartilage after trea...
Ngày tải lên : 09/08/2014, 01:24
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Báo cáo y học: "Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients" potx

Báo cáo y học: "Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients" potx

... single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients Matthias Pierer, Sylke Kaltenhäuser, Sybille Arnold, Matthias ... provide further evidence that the PTPN22 1858T allele is associated with RA irrespective of autoantibody production. The increas...
Ngày tải lên : 09/08/2014, 08:22
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Báo cáo y học: " Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab the" pdf

Báo cáo y học: " Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab the" pdf

... released in increased amounts in response to growth factors and proinflammatory cytokines, suggesting involvement in the pathophysiology of RA [24]. The few stud- ies of anti-MCV usually found performance ... widely expressed by mesenchymal cells and macrophages and easy to detect in the synovium. Modification of the protein occurs in macro- phages undergoing apoptosis, a...
Ngày tải lên : 09/08/2014, 13:22
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Báo cáo y học: "Offensive’ snakes: cultural beliefs and practices related to snakebites in a Brazilian rural settlement" docx

Báo cáo y học: "Offensive’ snakes: cultural beliefs and practices related to snakebites in a Brazilian rural settlement" docx

... substance as an antivenom is both historically ancient and geographically Table 3 Charms related to snakebites, according to the inhabitants of the county of Pedra Branca, Bahia State, Brazil. Charms ... pricking are synonymous and used as equivalent to offending. In this artic le, the word offense means a direct injury, real and/ or imaginary, caused by any animal to a...
Ngày tải lên : 10/08/2014, 09:21
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Báo cáo y học: "Cor triatriatum presenting as heart failure with reduced ejection fraction: a case report" pptx

Báo cáo y học: "Cor triatriatum presenting as heart failure with reduced ejection fraction: a case report" pptx

... bypas s (CPB) was achieved by standard ascending aorta and bicaval cannulation. Mildly hypothermic (32°C) CPB was established. Cold blood car- dioplegia was administered in an antegrade fashion through ... triatriatum. Cathet Cardiovasc Diagn 1992, 25:323-6. doi:10.1186/1749-8090-6-83 Cite this article as: Kokotsakis et al.: Cor triatriatum presenting as heart failure with redu...
Ngày tải lên : 10/08/2014, 09:21
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Báo cáo y học: "Delayed intracardial shunting and hypoxemia after massive pulmonary embolism in a patient with a biventricular assist device" pdf

Báo cáo y học: "Delayed intracardial shunting and hypoxemia after massive pulmonary embolism in a patient with a biventricular assist device" pdf

... CAS E REP O R T Open Access Delayed intracardial shunting and hypoxemia after massive pulmonary embolism in a patient with a biventricular assist device Thomas Weig 1* , Michael E Dolch 1 , ... months postpartum on a cardiac biventricular assist device (BVAD) as bridge to heart transplantation with delayed onset of intracardial shunting and subseque...
Ngày tải lên : 10/08/2014, 09:22
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Báo cáo y học: "Association between isotretinoin use and central retinal vein occlusion in an adolescent with minor predisposition for thrombotic incidents: a case report" doc

Báo cáo y học: "Association between isotretinoin use and central retinal vein occlusion in an adolescent with minor predisposition for thrombotic incidents: a case report" doc

... purposes) Journal of Medical Case Reports Open Access Case report Association between isotretinoin use and central retinal vein occlusion in an adolescent with minor predisposition for thrombotic incidents: ... documented case of this association. Case presentation: An otherwise healthy 17-year-old white man who was treated with systemic isotreti...
Ngày tải lên : 11/08/2014, 20:20
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Báo cáo y học: " Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B" pps

Báo cáo y học: " Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B" pps

... purposes) NTHi-induced COX-2 and PGE2 expression mediated by p38 MAPK and NF-kappa B signaling pathway To determine the role of NTHi-induced p38 MAPK and NF-kappa B activations in NTHi-induced COX-2 and PGE2 ... the inhibition of p38 MAPK. Conclusion: NTHi induces COX-2 and PGE2 expression in a p38 MAPK and NF-kappa B-dependent manne...
Ngày tải lên : 12/08/2014, 15:21
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Báo cáo y học: "Circulating immune complexes and complement C3 and C4 levels in a selected group of patients with rhinitis in Lebanon" pot

Báo cáo y học: "Circulating immune complexes and complement C3 and C4 levels in a selected group of patients with rhinitis in Lebanon" pot

... (65.5%). Dermatophagoides pteronyssinus (Dpt) was the causative allergen in 62, Dermatophagoides farinae (Df) in 58, cat hair dander in 23 and dog hair dander in 9 patients (some patients were allergic ... because C3 and C4 levels were within the normal range in all patients tested (Table 1). In support of the lack of involvement of the classical and lectin...
Ngày tải lên : 13/08/2014, 13:22
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Báo cáo y học: "Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury" pps

Báo cáo y học: "Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury" pps

... Silva et al., Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury Critical Care 2010, 14:R114 Silva et al. Critical Care ... 68:585-618. 33. Kulkarni AC, Kuppusamy P, Parinandi N: Oxygen, the lead actor in the pathophysiologic drama: enactment of the trinity of normoxia, hypoxia, and...
Ngày tải lên : 13/08/2014, 20:22
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Báo cáo y học: "Association between serum soluble CD40 ligand levels and mortality in patients with severe sepsis" potx

Báo cáo y học: "Association between serum soluble CD40 ligand levels and mortality in patients with severe sepsis" potx

... procalcitonin to determine its association with sCD40L levels. There are been reported an association between sCD40L levels and severity of acute coronary artery syndrome [31] and between tropo- nin and ... associated with mor- tality at 30 days in a large series of septic patients. We found higher serum sCD40L levels in patients with severe sepsis than in h...
Ngày tải lên : 14/08/2014, 08:21
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