... gastrointestinal tract: a paradisefor acronyms (GUMP, GIST, GANT, and now GIPACT). Implications of c-kit in genesis, and yet another of many emerging roles of the interstitialcell of Cajal in the pathogenesis ... pathogenesis of gastrointestinal disease. Adv AnatPathol 1999, 6:19-40.13. Miettinen M, Sarlomo-Rikala M, Lasota J: Gastrointestinal stromal tumours.Ann Chir Gynaecol1998, 87:278-281.14. Chiappa A, ... immunohistochemical markers have revolutionised the classification of gastrointestinal stromal tumours (GISTs) whilst tyrosine kinase inhibitors (imatinib) have had a significant impact onthe treatment of advanced...