Báo cáo y học: "Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians" potx
Báo cáo y học: "Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians" potx
... gene as a susceptibilityfactor for osteoarthritis (OA). Alleles of this microsatellitedetermine the variable number of aspartic acid residues in the amino-terminal end of the asporin protein. ... in normal cartilage but that is notably increased in OA cartilage[4]. Variant ASPN proteins are due to a microsatellite in the ASPN coding sequence that determines a variable number of aspartic acid ... The OA-associated allele, with 14 aspartic acid residues, inhibits the anabolic effects of transforming growth factor beta more strongly than other asporin alleles, leading to increased OA liability....
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Báo cáo y học: "Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis" ppt
... synthesis asso-ciated with inflammation in patients with OA and otherinflammatory diseases.ConclusionmPGES-1 was upregulated by proinflammatory cytokines in OA chondrocytes and was one of the key ... CCA ACG TGA GCT ATTGTG CAT CAA CAC AGG CGC CTC TTC32COX-2 1157 AGA CAG ATC ATA AGC GAG GGC CACT TGC ATT GAT GGT GAC TGT28GAPDH 598 CCA CCC ATG GCA AAT TCC ATG GCATCT AGA CGG CAG GTC AGG ... shown).Expression of mPGES-1 protein in articular cartilage from patients with OAArticular cartilage obtained from patients with OA was fixed in formaldehyde, embedded in paraffin, and cut into serialsections...
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Tài liệu Báo cáo Y học: Tissue factor pathway inhibitor A possible mechanism of action doc
... KXaÀVIIaÀTFD¼kXaÀVIIaÀTFdkVIIaÀTF;Xa a A2 2Þ In a similar fashion, the analysis of VIIa–TF inhibition by Xa–TFPI or with the help of hypothetical reaction of the enzyme–product complex inhibition ... [18], the constants for the VIIa–TF inhibition by Xa–TFPI were measured by analysis of factor Xa generation curves in the presence of Xa–TFPI.If the hypothetical reaction of Xa–VIIa–TF inhibition ... that: (a) the mechanism suggested by Baugh et al. [8] allowsquantitative description of the inhibitory action of TFPI on the kinetics of factor X activation in the absence of factorXa at the initiation...
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Báo cáo y học: "Atherogenic lipid profile is a feature characteristic of patients with early rheumatoid arthritis: effect of early treatment – a prospective, controlled study" pps
... the commencement of therapy. After one year of treatment, a significant clinical andlaboratory improvement was noted. This was correlated with changes in the lipid profile, mainly the increase ... and after one year of therapy. The baseline values of CETP activity in ERApatients were significantly higher compared to controls,whereas they were significantly reduced after one year of ther-apy ... mg/day). The dose of MTX remained stable during the study while the dose of prednisone was tapered according to a patient's clinical response. Disease activity was assessed bymeasuring the...
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Báo cáo y học: "Alkylating HIV-1 Nef - a potential way of HIV intervention" ppsx
... study.SJB involved in data analysis and revision of the manuscript. All authors readand approved the final manuscript.Jin et al. AIDS Research and Therapy 2010, 7:26http://www.aidsrestherapy.com/content/7/1/26Page ... lower than that on chymotrypsin and trypsin, sug-gesting higher alkylation specificity than that of serineproteases. (2) Z-FA-FMK, a structurally very similaralkylation reagent, is inactive in ... Mutagenesis analysis indicated that the modification occurred at Cys55 and Cys206 in Nef.Mass spectrometry demonstrated that the modification was a covalent attachment (alkylation) of TPCK at Cys55and...
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Báo cáo y học: "iagnostic Markers based on a Computational Model of Lipoprotein Metabolism" ppsx
... Packard CJ, Shepherd J, Lindsay GM, Gaw A, Taskinen MR: Thyroid replacement therapy and its influence on postheparin plasma lipases and apolipoprotein-B metabolism in hypothyroidism. J Clin ... from a group because of a lack of steady state in the data (in- and efflux balance), individual subjects are mentioned. - 17 - The calibrated model produced an analysis of lipoprotein kinetics ... et al. [24], and atorvastatin and simvastatin treatment in mixed dyslipidemic subjects from Forster et al. [25]. All these studies contain lipoprotein kinetics data at baseline and after each...
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Báo cáo y học: "Primary malignant pericardial mesothelioma - a rare cause of pericardial effusion and consecutive constrictive pericarditis: a case report" pps
... original work is properly cited.AbstractIntroduction: Primary malignant pericardial mesothelioma is a very rare pericardial tumor of unknown etiology.Case presentation: A 61-year-old Caucasian ... Primarypericardial mesothelioma. Lung Cancer 2008, 60:291-293.3. Maruyama R, Sakai M, Nakamura T, Suemitsu R, Okamoto T,Wataya H, Nishiyama K, Kamei T, Ichinose Y: Triplet chemother-apy for malignant ... tomography (FDG-PET/CT) scan demon-strated an intrapericardial accumulation of the tracer,indicating a local infection or a tumor (Figure 3) [1]. The patient’s level of intrapericardial fluid...
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Báo cáo y học: "Internal supravesical hernia as a rare cauase of intestinal obstruction: a case report" potx
... diagnosis and therapy.IntroductionSupravesical hernias develop at the supravesical fossabetween the remnants of the urachus and the left or rightumbilical artery. They have many anatomical variants ... other anatomical variants.Case presentation: A 60-year-old Senegalese man was admitted with a two-day history of smallbowel obstruction. A physical examination showed abdominal distension. An ... a CTscan can lead to a preoperative diagnosis. Laparoscopymay also be used for diagnosis and for therapy. A computed tomography scan showing an image (arrow) in the left iliac fossa that suggests...
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Báo cáo y học: "Impaired vascular responses to parasympathetic nerve stimulation and muscarinic receptor activation in the submandibular gland in nonobese diabetic mice." ppt
... neuropeptide Y (NPY), which aremainly found in parasympathetic and sympathetic nerves,respectively. This finding indicates increased release of VIPand NPY by salivary glands of SS patients [18].As ... membrane in aci-nar epithelial cells in rat salivary glands [42], and seems to be of parasympathetic origin since they are significantly reducedafter parasympathetic denervation [43]. In mouse ... throughout the glan-dular parenchyma, frequently surrounding the acinar epithelialcells. In areas surrounding the focal infiltrates, the staining pat-tern of the submandibular glands from NOD...
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Báo cáo hóa học: " Source Depth Estimation Using a Horizontal Array by Matched-Mode Processing in the Frequency-Wavenumber Domain" pot
... depth with a vertical line array (VLA) in order to extract the mode amplitudes. In this paper, we focus on horizontal l ine arr ays (HLA) asthey are generally more practical for at sea applications. ... Details of the transforma-tion and hypothesis are given in the Appendix. Then, the the-oretical f− k transform of the data recorded at long range,after range normalization, and on an in nite ... performedusing a horizontal line array. Extraction is based on the frequency-wavenumber transform of the recorded data andon mask filtering. Secondly, another specificity of the methodis that masks are...
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Từ khóa: chuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíChuong 2 nhận dạng rui roKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015MÔN TRUYỀN THÔNG MARKETING TÍCH HỢPQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ