Báo cáo y học: "Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupus" pot
Báo cáo y học: "Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupus" pot
... production of cytokines, and increased T cell stimulatory capacity before and after the onset of the disease [14].In our study we analyzed DCs in the original NZM2410 and NZB-W/F1 mice before and after ... No 2Research articleAbnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupusLucrezia Colonna1, Joudy-Ann Dinnall1, Debra K Shivers1, ... evi-dent only after the onset of the disease, the overexpression of CD40 precedes the onset of lupus and is sustained even dur-ing the course of the disease. We therefore propose that the decreased...
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Báo cáo y học: "Association between regulated upon activation, normal T cells expressed and secreted (RANTES) -28C/G polymorphism and asthma risk – A Meta-Analysis"
... author’s name, year of publica-tion, country of origin, ethnicity, type of asthma, number of cases and controls, and the minor allele fre-quency in controls. Meta-Analysis. The risk of asthma ... Immunol. 1993; 150: 3442-8. 24. Schall TJ, Bacon K, Toy KJ, et al. Selective attraction of monocytes and t lymphocytes of the memory phenotype by cytokine rantes. Nature. 1990; 347: 669-71. 25. ... severity [29]. Therefore, as one of the C-C chemokines, the RANTES polymorphisms necessarily resulted into the level of eosinophils elevating correspond, and then increased the individual risk of...
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Báo cáo y học: " Human embryonic stem cell (hES) derived dendritic cells are functionally normal and are susceptible to HIV-1 infection" pot
... celltherapy [9]. Recently we demonstrated derivation of phe-notypically and functionally normal macrophages fromhES-CD34+ cells and established that they could supportHIV-1 infection. These ... progenitor cells and spread via the bloodstream and lymphatics [12,13]. Theyare found in almost every organ as sentinels of the immune system. In innate immunity, DCs function viatype-1 interferon ... evaluation.Functional analysis of hES-DCs by Mixed Leukocyte Reaction (MLR) assay and antigen uptake assay The T cell stimulatory capacity of DCs derived from hES cells CD34+ progenitor cells was...
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Báo cáo y học: " Abnormal macrophage response to microbial stimulus in a 43-year-old man with a severe form of atherosclerosis: a case report" pptx
... assessment of the efficacy of drug therapy.IntroductionAtherosclerosis is the leading cause of death in the majority of industrialized countries. The absence of “tra-ditional” risk factors and the ... neces-sarily prove the existence of atherogenic effects,particularly in view of the widespread distribution of the microorganisms involved.Several authors have hypothesized that the number of different ... may provide an additional tool against atherosclerosis and its clinical complications. The evaluation of cell susceptibility before and after the correction of risk factors may contribute to the...
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Báo cáo y học: "B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin" pdf
... to that of APRIL homotrimers. The reduced potency of the heterotrimer ligands in the pri-mary human B cell-proliferation assay compared with the homotrimeric BLyS may be explained by the predo-minant ... the Hisx6-zz12.6 form of BLyS, and an ti-BLyS pAb followedby donkey anti-rabbit IgG-HRP for the trypsini zed form of BLyS. The molecular mass of the heterotrimers wasconfirmed by SEC-MALS mass distribution ... equally as active as the zzversions. This suggested tha t the zipper domain did notalter the biologic activity of these ligands in this assay.Atacicept and BCMA-Ig neutralized the activity of...
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Báo cáo y học: " Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment" pot
... production of reactiveoxygen species and inflammatory mediators by alveolarmacrophages (AM) [4-7] and epithelial [7-10] and otherlung cells [11]. When AM and airway epithelial cells aredirectly exposed ... dishes and cultured in BEGM. Light microscopy showed that95% of the isolated cells had features of bronchial epithe-lial cells, that is they formed a monolayer of ciliated cells. Also, by trypan ... of monocytes from the marrow as well as their recruitment into the lung. The close proximity of AM and epithelial cells in the lungsuggests that interaction between these cells is criticallyimportant...
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Báo cáo Y học: Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1 potx
... whetherhspry4 can be phosphorylated and palmitoylated similar tospry1 and spry2, and if TESK1 can interact with other spryproteins (directly). Finally, in view of the strength and specificity ... althoughfurther proof of a functional interaction is required. The relatively low levels of expression of the two proteins and the limited sensitivity/specificity of currently available polyclon-al ... sprouty(spry) gene family. Homology with murine spry4 (mspry4)was especially striking, i.e. 87% at the DNA and 88% at the protein level. Our novel gene was therefore named humanspry4 (hspry4)....
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Báo cáo y học: "Successful immunotherapy with matrix metalloproteinasederived peptides in adjuvant arthritis depends on the timing of peptide administration" pdf
... occurrence of MMP peptide-specific T cells during AA The PLN responses were analyzed in lymphocyte prolifera-tion assays at day 0 (naïve animals), day 10 (before clinical onset of disease), day 14 (onset ... such therapies.Acknowledgements The authors thank MC Grosfeld for the peptide–MHC binding assays. The research by Dr MHM Wauben was made possible by a fellowship of the Royal Netherlands Academy ... the percentage of the body weight at the time of AA induction. Data shown are the percentage of the body weight of twoexperiments (n = 10 rats per group) ± standard error of the mean. OVA323–339,...
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Báo cáo y học: " TGF β-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7" pps
... histological analysis of synovial fibrosis and PG content of the cartilage.HistologyKnee joints of mice were dissected and fixed in phosphate-buffered formalin for 7 days. Thereafter, they were decalcifiedin ... one of the synoviallining cells and thereby fully block the TGF-β-induced fibrosis.We have previously demonstrated that blocking TGF-β withAd-Smad7 in OA resulted in reduction of the synovial ... low point, and thereafter the incorpo-ration rapidly increases above normal incorporation levels. Byday 4, the incorporation of 35SO42- had significantly increasedto 165% of the normal...
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Báo cáo y học: "Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration" ppt
... design of the study, performed the majority of the laboratory work and analysis, and drafted the manuscript. AJF participated in the design of the study and interpretation of data. JAH conceived the ... to cytokines and growth factors[15]. Our data indicate that the senescent phenotype is linkedto the increased production of degradation enzymes whichmay be brought about by the catabolic cytokine ... expression of matrix-degrading enzyme genesReal-time PCR was performed for 18s, p16INK4a, MMP-13, and ADAMTS 5 using the standard curve method of analysison directly extracted cells and expanded cells. Primers...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyenbáo cáo khoa học y họcNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhát hiện xâm nhập dựa trên thuật toán k meansSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ