Báo cáo y học: "roteoglycan 4 downregulation in a sheep meniscectomy model of early osteoarthritis" docx

... functional properties of synovial joints. A focal decrease in PRG4 in early OA couldhave a role in the pathogenesis of cartilage degeneration. In the present study we have demonstrated in an animal ... CR: Topographic variation in big-lycan and decorin synthesis by articular cartilage in the early stages of osteoarthritis: an experimental study in sheep. JOrthop Res 1996, 14: 433 -44 4.18. Wong ... proteoglycan 4 expression andlocalisation in the early phases of the disease. In normal controljoints, proteoglycan 4 was immunolocalised in the superficialzone of cartilage, particularly in those...

Báo cáo y học: "“Floating arm” injury in a child with fractures of the proximal and distal parts of the humerus: a case report" docx

... publication• PubMed indexing• Inclusion in Cases DatabaseAny patient, any case, can teach ussomethingwww.casesnetwork.comPage 4 of 4 (page number not for citation purposes)Journal of Medical ... injury. Hecomplained of pain in the left elbow and shoulder. Theproximal part of the left arm and elbow had swelling andcrepitus. His neurovascular examination was normal.Plain radiographs ... forearm. Arch OrthopTrauma Surg 2000, 120:205-208.5. Gül A, Sambandam S: Ipsilateral proximal and flexion supra-condylar humerus fracture with an associated olecranonfracture in a 4- year-old...

Báo cáo y học: "Emergency intraosseous access in a helicopter emergency medical service: a retrospective study"

... critically ill patients in emergency situations. As part of their HEMS trainingprogramme, intraosseous training was given using man-ual needles, Bone Injection Guns, and EZ-IO® on bothmanikins and ... resuscitation of criti-cally ill or injured adult and paediatric patients [1,2]. Itcan be challenging to obtain vascular access, especially in the resuscitation of small children in emergencysituations ... Heltne1,2,3AbstractBackground: Intraosseous access (IO) is a method for providing vascular access in out -of- hospital resuscitation of critically ill and injured patients when traditional intravenous access...

Báo cáo y học: "Primary Care Outcomes in Patients Treated by Nurse Practitioners or Physicians" docx

... withpatient interviews at 6 months after initial appointment and health services utilizationdata recorded at 6 months and 1 year after initial appointment.Setting Four community-based primary care ... clinics (17 physicians) and 1 primarycare clinic (7 nurse practitioners) at an urban academic medical center.Patients Of 3397 adults originally screened, 1316 patients (mean age, 45 .9 years;76.8% ... maintained in theinitially assigned group for the analy-ses, consistent with an intent-to-treatanalysis. All analyses were repeated with-out these 159 patients, and the resultswere the same.RESULTSRecruitment,...

Báo cáo y học: "5HT2A polymorphism His452Tyr in a German Caucasian systemic sclerosis population" ppt

... [7], as reported for theItalian population.HapMap data reveal considerable variation of Tyr452 fre-quency among populations. It is especially high withinAfricans, emphasizing the importance of ... (ANA-positive), 43 % anticentromere antibodies (ACA-positive),39% antitopoisomerase I antibodies (ATA-positive), and theyhad a mean age of disease onset of 49 .5 ± 13.8 years. Massspectrometry-based genotyping ... sero-tonin activity [2]. Beretta and colleagues also demonstratedthat plasma from healthy heterozygous carriers of His452Tyrshowed decreased platelet aggregation after serotoninstimulus compared...

Báo cáo y học: "Complex cytokine effects in a complex autoimmune disease: tumor necrosis factor in systemic lupus erythematosus" potx

... rheuma-toid synovial hyperplasia and a clinical benefit of anti-TNF-alpha therapy for RA. Cytokine 2000, 12:281-288.59. Yamasaki S, Kawakami A, Nakashima T, Nakamura H, Kamachi M,Honda S, Hirai ... may explain why TNF blockadecan induce increases in antinuclear antibodies and at thesame time rapidly reduce inflammation and prevent inflam-mation-induced damage, also observed in SLE patients.These ... 141 :1197-1201.76. Takemura T, Yoshioka K, Murakami K, Akano N, Okada M, Aya N,Maki S: Cellular localization of inflammatory cytokines in human glomerulonephritis. Virchows Arch 19 94, 42 4 :45 9 -46 4.77....

Báo cáo y học: "Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume" pps

... Cicuttini F: Early radio-graphic osteoarthritis is associated with substantial changes in cartilage volume and tibial bone surface area in both malesand females. Osteoarthritis Cartilage 20 04, ... per grade = 4. 89, 95% CI = 1.59–15.02). Two-year longitudinal datarevealed that medial meniscal extrusion at baseline wasassociated with a greater rate of loss of medial tibiofemoralcartilage ... medial joint space nar-rowing and osteophytes at baseline, loss of medial tibial carti-lage volume, and progression of tibiofemoral cartilage defectscore.Age, sex and family history of OA were...

Báo cáo y học: "5HT2A polymorphism His452Tyr in a German Caucasian systemic sclerosis population - authors’ response" docx

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Báo cáo y học: "Whole exome capture in solution with 3 Gbp of data" pps

... an increase in initial library com-plexity arising from better annealing efficiencies of theIllumina adapter. This is probably explained by the factthat Illumina adaptor sequences contain an ... 73% and the duplicate rate to nearly quadruple to27.6%, virtually identical to the Illumina frag libraryduplicate rate. The net effect of using PE data instead of frag data was a significant increase ... sample using either SOLiD orIllumina sequencing. Using approximately 10 Gbp of SOLiD data, approximately 93% of all HapMap variantsare discovered and over 88% of all variants are present in dbSNP....

Báo cáo y học: "Ectopic cervical thymoma in a patient with Myasthenia gravis" docx

... Photomicrography s (hematoxylin and eosin staining). (A) Lobules separated by thick fibrous bands (× 40 ). (B) Microscopicfindings of transition between lymphocyte-rich area and thelymphocyte-poor oval ... thyroid gland (Figure 2). The cut surface of thetumor was tan-colored with no areas of necrosis. A total of 40 gm of thymic tissue was removed additionally.The anatomopathological examination ... lymphocyte-poor spindle cellareas and lymphocyte-rich areas. These histopathologicfindings were consistent with a type AB according toWorld Health Organization Classification System(WHO), Masaoka...

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