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Báo cáo y học: "Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study" pptx

Báo cáo y học:

Báo cáo y học: "Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study" pptx

... citation purposes) effects of the different NSAIDs should be consistent in vitro and in vivo.The direct negative effects of indomethacin are mainlyreflected by an inhibition of proteoglycan synthesis ... features in terms of proteoglycan turnover (Table 1): low proteoglycan synthesis, high proteoglycan release (both newly formed pro-teoglycans and resident proteoglycans) and diminished prote-oglycan ... percent-age release of glycosaminoglycans (normalized to the glycosaminogly-can content); and (d) proteoglycan content (proteoglycan content). White bars represent effects of indomethacin (10 µmol/l);...
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Tài liệu Báo cáo Y học: Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils pot

Tài liệu Báo cáo Y học: Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils pot

... synthetase, inhibition of CoA-IT results in an increase in free AA and a corresponding build-up of AA in triacylglycerols that can be prevented by co-incubation of cells with CoA-synthetase inhibitors ... & Snyder, F. (1973) The enzymicincorporation of arachidonic acid into ether-containing cholineand ethanolamine phosphoglycerides by deacylation-acylationreactions. Biochim. Biophys. Acta ... radioactivity imaging system (Washington, DC,USA) and the amount of radioactivity migrating with PAFwas determined by zonal scraping, followed by liquidscintillation counting.Determination of 5-LO...
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Báo cáo y học:

Báo cáo y học: "Lifetime health effects and medical costs of integrated stroke services - a non-randomized controlled cluster-trial based life table approach"

... additional training and a trans-mural stroke nurse was in charge of patient transfers.This was the only fully integrated stroke service asdefined ex ante, and was the only one cost-effective in the ... strokemorbidity rates using a disability-based two-state transi-tion model combining population projections and exist-ing data on stroke epidemiology. Their projectionsindicated that the aging of the ... institutionalized rehabilitation by amultidisciplinary team [33]. However, length of stay in stroke units may vary within Europe and this maychange the financial, short-term, impact of stroke...
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Tài liệu Báo cáo Y học: Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor pot

Tài liệu Báo cáo Y học: Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor pot

... transduction pathways were analyzedby studying the activation level of JAK/STAT and MAPkinase signaling components known to be mainly tyrosinephosphorylated in response to IL-6 type cytokines ... and/oradditional transfection of the human LIF-R were stimulatedwith increasing amounts of Hyper-IL-6, Hyper-CNTF, LIFor medium alone. Proliferation of cells was assayed bymeasuring [3H]thymidine incorporation ... C-terminus of the extracellular domain of human CNTF-R (amino acids 1–346) was linked via a single glycineresidue to the N-terminus of human CNTF (amino acids1–186). Recombinant Hyper-CNTF protein...
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Báo cáo Y học: Differential regulation of the Fe-hydrogenase during anaerobic adaptation in the green alga Chlamydomonas reinhardtii pot

Báo cáo Y học: Differential regulation of the Fe-hydrogenase during anaerobic adaptation in the green alga Chlamydomonas reinhardtii pot

... [27].MATERIALS AND METHODSAlgae strains, culture conditions and anaerobicadaptationWild-type Chlamydomonas reinhardtii 137c(mt+) strainwas originally obtained from the Chlamydomonas CultureCollection ... of hydA contains a 1494-bp ORFencoding a protein with an apparent molecular mass of 53.1 kDa. The t ranscription of the hydrogenase gene isvery rapidly induced during anaerobic adaptation of ... Thefermentation of organic compounds is associated withhydrogen evolution. The key enzyme hydrogenase, which issynthesized only after an anaerobic adaptation, catalyzesthe reversible reduction of protons...
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Báo cáo Y học: Differential scanning calorimetric study of myosin subfragment 1 with tryptic cleavage at the N-terminal region of the heavy chain pdf

Báo cáo Y học: Differential scanning calorimetric study of myosin subfragment 1 with tryptic cleavage at the N-terminal region of the heavy chain pdf

... far from actin-bindingsites in the 3D structure of S1 [28], these effects of actin canbe explained by long-range conformational changes inducedby the attachment of actin to its binding sites, ... contact may serve as an additional communica-tion pathway between the motor domain and the regula-tory domain, and it may play a crucial role in thetransmission of actin-induced conformational ... N-terminal region of theS1 heavy chain plays an important role in structural stabili-zation of the entire motor domain of the myosin head, and along-distance communication pathway may exist...
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Báo cáo Y học: Differential regulation of telomerase activity by six telomerase subunits potx

Báo cáo Y học: Differential regulation of telomerase activity by six telomerase subunits potx

... Tung-Chieh Chang1, Yin-Ling Chen2, Huei-Ting Yang2, Chi-Yuan Chen2and Ann-Joy Cheng21Department of Radiation Oncology, Chang Gung Memorial Hospital, Taoyuan, Taiwan;2School of Medical ... activity of reconstituted telomerase in cell extracts, demonstratingthe role of hsp90 in the holoenzyme complex [36]. In our in vitro and cellular study of antisense oligonucleotide inhibition, ... TEP1, have an additional stimulatory effect on telomerase requires furtherinvestigation. Antisense inhibition of dyskerin, althoughshowing comparable inhibition of telomerase function in cells,...
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Báo cáo y học:

Báo cáo y học: "Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages" docx

... Pro-inflammatory cytokines may also control protein ex-pression of TLRs on the cell surface and intracellularly through regulation of inhibitory RNA pathways, pro-tein translation and post-translational ... TLR2 and TLR4 in neutrophils and monocytes. GM-CSF up-regulated expression of TLR2 and TLR4 in neutrophils and TLR2 in monocytes. TLR5 was down-regulated by inflammatory cytokines in monocytes. ... relative importance of TLR2 and TLR4 in anti-bacterial innate immunity surveillance. Alterna-tively, they suggest that separate expression control of TLR5 by inflammatory cytokines may contribute...
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Báo cáo y học:

Báo cáo y học: "Costs and effects of paliperidone extended release compared with alternative oral antipsychotic agents in patients with schizophrenia in Greece: A cost effectiveness study" pdf

... dis-continue prior to the end of the year may switch toanother oral atypical antipsychotic or discontinue antip-sychotic medication altogether. If they discontinue antip-Annals of General Psychiatry ... thediscontinuation of patients during the year of study.Treated EPS and clinically significant weight gain (≥7%increase of body weight compared to baseline), which arefrequent side effects of ... Effectiveness of olanzapine, quetiapine,risperidone, and ziprasidone in patients with chronic schizo-phrenia following discontinuation of a previous atypicalantipsychotic. Am J Psychiatry 2006,...
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Báo cáo y học:

Báo cáo y học: "Costs and effects of paliperidone extended release compared with alternative oral antipsychotic agents in patients with schizophrenia in Greece: a cost effectiveness study" ppsx

... schizophrenia in Greece: a costeffectiveness study. Annals of General Psychiatry 2008, 7:16.Table 1: Mean annual number of stable days and cost per patient by pharmaceutical treatment.Paliperidone ER ... archived on PubMed Central yours — you keep the copyrightSubmit your manuscript here:http://www.biomedcentral.com/info/publishing_adv.aspBioMedcentralAnnals of General Psychiatry 2009, 8:15 ... Kousoulakou H, Ollandezos M, Athanasakis K, Papanico-laou S, Kyriopoulos I: Costs and effects of paliperidoneextended release compared with alternative oral antipsy-chotic agents in patients with...
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