... Tung-Chieh Chang1, Yin-Ling Chen2, Huei-Ting Yang2, Chi-Yuan Chen2and Ann-Joy Cheng21Department of Radiation Oncology, Chang Gung Memorial Hospital, Taoyuan, Taiwan;2School of Medical ... activity of reconstituted telomerase in cell extracts, demonstratingthe role of hsp90 in the holoenzyme complex [36]. In our in vitro and cellular study of antisense oligonucleotide inhibition, ... TEP1, have an additional stimulatory effect on telomerase requires furtherinvestigation. Antisense inhibition of dyskerin, althoughshowing comparable inhibition of telomerase function in cells,...