... of neither of these pathways was inhib-ited by ATRA. As a reduced phosphorylation of p38 wasthought to contribute to the inhibitory effect of ATRA on IL-1-induced expression of cytokines in ... inhibition of tpl2 blocks inflammatory responses in pri-mary human monocytes, synoviocytes, and blood. J Biol Chem2007, 282 :33 295 -33 304. 37 . Georganas C, Liu H, Perlman H, Hoffmann A, Thimmapaya B,Pope ... TR: Retinoylation of the cAMP-binding regulatory subunits of type I and type IIcAMP-dependent protein kinases in HL60 cells. Arch BiochemBiophys 1991, 290:2 93- 302.48. Tournier S, Raynaud F,...