Báo cáo khoa học: "Stage II/III rectal cancer with intermediate response to preoperative radiochemotherapy: Do we have indications for individual risk stratification?" pdf

Báo cáo khoa học: MicroRNA-143 reduces viability and increases sensitivity to 5-ﬂuorouracil in HCT116 human colorectal cancer cells potx

... 5-FU cytotoxicityFEBS Journal 276 (2009) 66896700 ê 2009 The Authors Journal compilation ê 2009 FEBS 6699 MicroRNA-143 reduces viability and increases sensitivity to 5-ﬂuorouracil in HCT116 human ... apoptosis-inducing drug; indeed,it was shown previously that 5-FU induces apoptosis in HCT116 cells [20]. 5-FU has been used in the clinic forseveral decades, and its metabolic pathways and cyto-toxic ... [27] and found mainly in thecytoplasm, where it was more intense in the ascendingmore differentiated pre-apoptotic glandular cells than in the immature, proliferating cells at the bottom ofcrypts....

Báo cáo khoa học: Stage speciﬁc expression of poly(malic acid)-afﬁliated genes in the life cycle of Physarum polycephalum Spherulin 3b and polymalatase potx

... 1046–1055 ª 2006 The Authors Journal compilation ª 2006 FEBS 1049 Stage speciﬁc expression of poly(malic acid)-afﬁliated genes in the life cycle of Physarum polycephalum Spherulin 3b and polymalatase Nadthanan ... Among them, spheru-Fig. 2. Structural alignment of amino acid sequence by motifs, of spherulin 3b with spherulin 3a and other members of the bc-crystallin fam-ily: (1) spherulin 3b from P. polycephalum; ... of microgram quantities of protein util-izing the principle of protein-dye binding. Anal Biochem72, 248–254.N. Pinchai et al. Cell type expression of spherulin 3b and polymalatase FEBS Journal...

Báo cáo khoa học: BRCA1 accumulates in the nucleus in response to hypoxia and TRAIL and enhances TRAIL-induced apoptosis in breast cancer cells pdf

... Journal compilation ê 2007 FEBS 5145 BRCA1 accumulates in the nucleus in response to hypoxia and TRAIL and enhances TRAIL- induced apoptosis in breast cancer cells Latricia D. Fitzgerald1,*, Charvann ... TRAIL induces apoptosis. The inability of hypoxia to cause apoptosis was not surprising, consid-ering the number of reports demonstrating that hypoxia blocks TRAIL- induced apoptosis. There aretwo ... Thus, these data support the hypothesis that BRCA1 enhances TRAIL s ability to mediate apoptosis in breast cancer cell lines.DiscussionThere is increasing interest in the association betweenhypoxia...

Báo cáo khoa học: Stage-speciﬁc activation of MIG-17⁄ADAMTS controls cell migration in Caenorhabditis elegans docx

... results indicate that activation of MIG-17occurred in the basement membranes of the muscle,intestine and gonad in the L3 larvae.We next studied the activation of MIG-17 in adultanimals expressing ... staining of intestinaland muscular basement membranes was often faintand discontinuous (Fig. 5C). In the older adults,ABCDEFFig. 4. MIG-17 activation in L3 larvae. (A–D)Cross-sections of ... Fluorescein–phalloidin labeled actin in the outer surface of body wall muscle cells.(E) Coimmunostaining of anti-prodomain(pink) and Monoclonal 2 (green). Overlap of the two antibody stains appears...

Báo cáo khoa học: Stage-speciﬁc expression of Caenorhabditis elegans ribonuclease H1 enzymes with different substrate speciﬁcities and bivalent cation requirements ppt

... expression of Caenorhabditis elegans ribonuclease H1 enzymes with different substrate specificities and bivalent cation requirements Hiromi Kochiwa1,2, Mitsuhiro Itaya1,3, Masaru Tomita1,4 and Akio ... duplication within the C. elegans genome. In summary, C. elegans RNase H1 enzymes Table 2. Specific activities of Ce-RNH1a and Ce-RNH1b in the pres-ence of Mg2+or Mn2+ions. One unit of enzymatic ... theprocessing of Okazaki-primer RNA.Results and DiscussionPrimary structures of multiple RNase H1 enzymes in C. elegans Four RNase H1- related genes have been identified inC. elegans, and one of them...

báo cáo khoa học: "Prognostic factors in patients with node-negative gastric cancer: an Indian experience" pdf

... RESEARCH Open AccessPrognostic factors in patients with node-negative gastric cancer: an Indian experienceRamakrishnan A Seshadri1*, Sunil B Jayanand1and Rama Ranganathan2AbstractBackground: ... gastric cancer, we wished to study the factors influencing thesurvival in Indian patients with node-negative gastric cancer, most of whom have advanced gastric cancer.This will help in the o ... Although the incidenceof gastric cancer in Indi a is less than other Asian coun-tries like Japan, Korea and China, the age-standardized(world) incidence of gastric cancer in Chennai (12.2 and6.0/100,000...

báo cáo khoa học: "Recurrent differentiated thyroid cancer: to cut or burn" pot

... ofregional or distant metastasis, or older patients withoutextrathyroidal localization, either out of the thyroidalcapsule or at distance or without extrathyroidal localiza-tion or out of the thyroidal ... multifocality does notappear to be a significant risk factor in the developmentof local recurrence in patients who undergo total thyroi-dectomy (TT) or near total thyroidectomy (NTT) [23].When LR ... Edited by: Rosato L. GSEditrice, Santhià; 2008:257-261.doi:10.1186/1477-7819-9-89Cite this article as: Cirocchi et al.: Recurrent differentiated thyroid cancer: to cut or burn. World Journal...

báo cáo khoa học: "Double primary malignancies associated with colon Cancer in patients with Situs Inversus Totalis: Two Case Reports" pptx

... low anterior resection (black arrows). Double primary malignancies associated with colon Cancer in patients with Situs Inversus Totalis: Two Case Reports Young Wan Kim1, Hoon Ryu1, Dae ... versions will be made available soon.Double primary malignancies associated with colon Cancer in patients with Situs Inversus Totalis: Two Case ReportsWorld Journal of Surgical Oncology 2011, ... either situs inversus totalis (SIT) or partial situs inversus. Unlike partial situs inversus, in cases of SIT, the left and right aspects of the thoracic and intra-abdominal organs are inverted...

Báo cáo khoa học: "Stage II/III rectal cancer with intermediate response to preoperative radiochemotherapy: Do we have indications for individual risk stratification?" pdf

... is properly cited.ResearchStage II/III rectal cancer with intermediate response to preoperative radiochemotherapy: Do we have indications for individual risk stratification?Thilo Sprenger*1, ... article as: Sprenger et al., Stage II/III rectal cancer with intermediate response to preoperative radiochemotherapy: Do we have indications for individual risk stratification? World Journal ... patients with rectal adenocarcinoma, 107 patients with stage II/III cancers and intermediate response to preoperative 5-FU based RCT (ypT2/3 and TRG 2/3), treated within the German Rectal Cancer...

Báo cáo khoa học: "Middle bile duct cancer with portal vein tumor thrombus" pps

... of middle bile duct cancer with portal vein tumor thrombus.Background Bile duct cancer (BDC), classified as cancer of the middleor distal bile duct, was the 6th leading cause of cancer- related ... adiagnosis of middle bile duct cancer with portal vein tumor thrombus, the patient underwentsurgery. At laparotomy, the main tumor was found to be located in the middle bile duct with a tumor thrombus, ... figure, main tumor shows red arrow in the main bile duct and portal vein shows yellow arrowFigure 2a and b. A schematic figure, main tumor shows red arrow in the main bile duct and portal vein shows...

Báo cáo khoa học: "Clinical efficacy and problems with CT lymphography in identifying the sentinel node in breast cancer" docx

... method, CTLG: CT Lymphography Table 5: Number of lymph vessels leading to Sentinel nodes and the number of Sentinel nodesSingle rout and Single node 151(68%)Multi routs and single node 8(4%)Single ... clearenhancing of the lymph nodes in 88% of the patients,while in 5% of the patients identification of the SN waspossible on the basis of the CT value in spite of the factthat the lymph nodes were ... Journal of Surgical OncologyOpen AccessResearchClinical efficacy and problems with CT lymphography in identifying the sentinel node in breast cancerMasako Takahashi1, Mitsunori Sasa*2,...

Báo cáo khoa học: "Long-term results from a randomized phase II trial of neoadjuvant combined-modality therapy for locally advanced rectal cancer" ppt

... RESEA R C H Open AccessLong-term results from a randomized phase II trial of neoadjuvant combined-modality therapy for locally advanced rectal cancerVaneja Velenik*, Irena Oblak, Franc AnderluhAbstractBackground: ... meta-analysis. JAMA 2000,284:1008-1015.2. Colorectal Cancer Collaborative Group: Adjuvant radiotherapy for rectal cancer: a systematic overview of 8,507 patients from 22 randomisedtrials. Lancet ... regarding the use of adjuvant therapy in patients with locally advanc ed rectal ca ncerhave yet to be answered, and da ta regarding capecita-bine in this setting are limited, it is clear that...

Báo cáo khoa học: "A single centre experience with sequential and concomitant chemoradiotherapy in locally advanced stage IV tonsillar cancer" doc

... 9 of 10 RESEARC H Open AccessA single centre experience with sequential and concomitant chemoradiotherapy in locally advanced stage IV tonsillar cancerRobin J D Prestwich*†, Kiran Kancherla†, ... 2001,127(2):135-9.doi:10.1186/1748-717X-5-121Cite this article as: D Prestwich et al.: A single centre experience with sequential and concomitant chemoradiotherapy in locally advanced stage IV tonsillar cancer. Radiation Oncology 2010 5:121.Submit ... al: Concomitant chemoradiotherapy versus induction docetaxel, cisplatin and 5 fluorouracil (TPF) followed by concomitant chemoradiotherapy in locally advanced head and neck cancer: a phase II randomized...

Báo cáo khoa học: " Comparison of rectal volume definition techniques and their influence on rectal toxicity in patients with prostate cancer treated with 3D conformal radiotherapy: a dose-volume analysis" ppt

... AccessResearch Comparison of rectal volume definition techniques and their influence on rectal toxicity in patients with prostate cancer treated with 3D conformal radiotherapy: a dose -volume analysisCem ... Vavassori V, Sanguineti G, Bianchi C, Cattaneo GM, Piaz-zolla A, Cozzarini C: Rectum contouring variability in patients treated for prostate cancer: impact on rectum dose -volume histograms and ... techniques of rectal contouring significantly influence the calculation of radiation doses to the rectum and the prediction of rectal toxicity. Rectal volume receiving higherdoses (≥ 70 Gy) and mean rectal...

Báo cáo khoa học: "Cutaneous vascular reactivity and flow motion response to vasopressin in advanced vasodilatory shock and severe postoperative multiple organ dysfunction syndrome" pot

... 2ResearchCutaneous vascular reactivity and flow motion response to vasopressin in advanced vasodilatory shock and severe postoperative multiple organ dysfunction syndromeGünter Luckner1, Martin W Dünser1, ... distribution in microcir-culation after arginine vasopressin- induced arteriolar vaso-Key messagesã Supplementary AVP infusion in patients with advanced vasodilatory shock and severe postoperative multiple ... with advanced vasodilatory shock and severe postoperative multiple organ dysfunction syndrome did not compromise cutaneous reactivehyperaemia and flowmotion when compared with norepine-phrine infusion...

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