Báo cáo y học: "Class effect of pharmacotherapy in bipolar d

Báo cáo y học: "Class effect of pharmacotherapy in bipolar disorder: fact or misbelief" pptx

... double-blind, placebo-controlled efficacy and safety study of quetiapine or lithium as monotherapy for mania in bipolar disorder. J Clin Psychiatry 2005, 66:111-121. 66. McElroy SL, Martens BE, Winstanley ... double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitated patients di...

Ngày tải lên : 09/08/2014, 01:21

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Báo cáo y học: "Lithium alters brain activation in bipolar disorder in a task- and state-dependent manner: an fMRI study" ppt

... S, Raymont V, Frangou S: The Maudsley Bipolar Disorder Project: the effect of medication, family history, and duration of illness on IQ and memory in bipolar I disorder. J Clin Psychiatry 2003, ... effect in either group in a working memory task. Interestingly, in previous work in healthy volunteers (unpublished information) using the same two cognitive tests we found th...

Ngày tải lên : 08/08/2014, 21:20

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Báo cáo y học: "Different effect of exercise on left ventricular diastolic time and interventricular dyssynchrony in heart failure patients with and without left bundle branch block"

... dyssynchrony during dobutamine stress in patients with wide QRS duration (20). In contrast, Kurita et al. reported on an increased mechanical dyssynchrony during pacing–induced tachycardia in ... mechanical dyssynchrony. These findings may further explain why patients with normal QRS duration may benefit from cardiac re- synchronization whether or not they have mechanical dyssy...

Ngày tải lên : 05/11/2012, 11:32

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Báo cáo Y học: The effect of amino-acid substitutions I112P, D147E and K152N in CYP11B2 on the catalytic activities of the enzyme pdf

... being attributed to the N-terminal part of human CYP11B2. Keywords: c ytochrome P450; 11 b-hydroxylase, aldosterone synthase; N-terminal protein region; engineering substrate speciﬁcity. Cytochromes ... CYP11B2 mutants in relation to the wild-type enzyme, when incubated with 11-deoxycortisol. The 11b-hydroxylation of 11-deoxycortisol catalysed by the mutated proteins is shown as percent...

Ngày tải lên : 24/03/2014, 03:21

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Báo cáo y học: " Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis" pptx

... interplay between several systemic factors and an array of local factors such as cytokines, inflammatory mediators and growth factors. As well as IL-1β, TNFα, and IL-6, local inflammatory mediators, ... RANKL.for RANKL.rev 5'-TGGAAGGCTCATGGTTGGAT-3' 5'-CATTGATGGTGAGGTGTGCAA-3' COX-2, cyclooxygenase-2; iNOS, inducible nitric oxide synthase; OPG, osteoprotegerin; RANK, r...

Ngày tải lên : 09/08/2014, 06:23

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Báo cáo y học: " Inhibitory effect of ribbon-type NF-κB decoy oligodeoxynucleotides on" potx

... inhibitory effect of RNODN on the induction and activity of osteoclasts. Direct intra-articular injection of RNODN into the joints may be an effective strategy for the treatment of arthritis. Introduction Osteoclasts ... Hayashi S, Higaki J, Ogihara T: Transcription factor decoy for nuclear factor-κB inhibits tumor necrosis factor-α-induced expression of interleukin-6 and intracel...

Ngày tải lên : 09/08/2014, 08:22

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Báo cáo y học: "Therapeutic effect of the potent IL-12/IL-23 inhibitor STA-5326 on experimental autoimmune uveoretinitis" pot

... necessary for EAU induction [24]. The nuclear factor (NF) κB is a popular target for effective blockade of activation of the promoter for genes encoding proinflammatory cytokines in cells involved in ... dose of 5 mg/kg or 20 mg/kg or vehicle only was orally administered once a day six days a week from day 0 to day 14 after immunization with human interphotoreceptor retinoid b...

Ngày tải lên : 09/08/2014, 13:22

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Báo cáo y học: "Suppressive effect of secretory phospholipase A2 inhibitory peptide on interleukin-1β-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice" ppt

... inhibition of sPLA 2 may logically block the formation of a wide variety of secondary inflammatory mediators. In our search for such an inhibitor, we designed a 17-residue peptide (P-NT.II) using the ... limited efficacy in clinical studies [14,15]. One of the potential rea- sons for the failure of LY333013 may be incomplete inactiva- tion of sPLA 2 in the SF due to inadequ...

Ngày tải lên : 09/08/2014, 14:22

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Báo cáo y học: "The effect of high correlated colour temperature office lighting on employee wellbeing and work performance" ppt

... were offered seating in a different part of the building. Individuals were informed that the aim of the study was to assess the acceptability of a new type of indoor lighting. They were informed ... out- door illuminance typically ranges between 2000 and 100,000 lux, indoor office illuminance is usually consid- erably lower, with norms of approximately 500 lux. More- over, typical...

Ngày tải lên : 10/08/2014, 09:20

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Báo cáo y học: "The effect of tight glycaemic control, during and after cardiac surgery, on patient mortality and morbidity: A systematic review and meta-analysis" pptx

... post-operatively, may reduce mortality and morbidity in cardiac surgery patients. The effect of tight glycaemic control on mortality following cardiac surgery The results of our meta-analysis on early mortality, including ... result of the meta-analysis for early mortality data. “Early mortality” was defined as death in CCU or within 30 days. Only three of the seven studies pr...

Ngày tải lên : 10/08/2014, 09:23

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