Báo cáo y học: "Adrenal suppression: A practical guide to the screening and management of this under-recognized complication of inhaled corticosteroid therapy" pptx

... Open AccessAdrenal suppression: A practical guide to the screening and management of this under-recognized complication of inhaled corticosteroid therapyAlexandra Ahmet1*, Harold Kim2,3 and ... in the diagnosis and management of asthma over the past decade, as wellas the availability of comprehensive and widely-acceptednational and international clinical practice guidelines forthedisease[6,7],asthmacontrolinCanadaremainssuboptimal. ... Spier4Abstract Inhaled corticosteroids (ICSs) are the most effective anti-inflammatory agents available for the treatment of asthma and represent the mainstay of therapy for most patients with the...

Báo cáo y học: " Chemokine blockade: a new era in the treatment of rheumatoid arthritis" ppsx

... forclinical use, there was also a marked reduction insymptoms and histopathology if the antagonist was givenonly after the disease had already developed. The protective effect on cartilage and bone ... of one ligand or receptormay be compensated for by other members of the superfamily. In addition, some ligands may be agonists atone receptor and antagonists at others. Another issue isthat ... and other chronic inflammatory disorders.Keywords: chemokines, rheumatoid arthritis, synovial tissue9721. Ogata H, Takeya M, Yoshimura T, Takagi K, Takahashi K: The role of monocyte chemoattractant...

Báo cáo y học: "Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score" potx

... index.Because calculation of the SDAI (and of the DAS28) is fre-quently limited at the time of the patient's visit either by a waitfor laboratory results or their unavailability, omitting the APRfrom ... in the SDAI. A purely clinical score is a valid measure of diseaseactivity and will have its greatest merits in clinical practice ratherthan research, where APRs are usually always available. ... HealthOrganization–International League of Associations for Rheu-matology) core set variables of disease activity [13-15] areavailable, such as the Disease Activity Score (DAS) [16]. Alsoavailable are...

Báo cáo y học: "T-614, a novel immunomodulator, attenuates joint inflammation and articular damage in collagen-induced arthritis" docx

... Sense Antisenseβ-actin 5'-AGGCCAACCGTGAAAAGATG-3' 5'-ACCAGAGGCATAC AGGGACAA-3'IFN-γ 5'-GAAAGACAACCAGGCCATCAG-3' 5'-TCATGAATGCATCCTTTTTTGC-3'IL-4 5'-CCACGGAGAACGAG ... 5'-CCACGGAGAACGAG CTCATC-3' 5'-GAGAACCCCAGACTTGTTCTTCA-3'IL-17 5'-GGGAAGTTGGACCACCACAT-3' 5'-TTCTCCACCCGGAAA GTGAA-3'Arthritis Research & Therapy Vol ... infiltration and participate in a number of inflammatory and destructive events, such as synovial hyperplasia, pannus for-mation, cartilage and bone erosion, and joint malformation [5-8]. RA was...

Báo cáo hóa học: " Research Article A New Method for Least-Squares and Minimax Group-Delay Error Design of Allpass Variable Fractional-Delay Digital Filters" pdf

... usuallystable when mean delay of the desired response is equal to the order of the designed allpass ﬁlter and the range of adjustableparameter is properly assigned. This paper is organized as ... section. To evaluate the accuracy of the designed system, the normalized root-mean-squared group-delay error, the maxi-mum group-delay error, the normalized root-mean-squaredphase error, and the maximum ... Minimax Group-DelayError Design of Allpass Variable Fractional-Delay Digital FiltersCheng-Han Chan,1Soo-Chang Pei (EURASIP Member),2 and Jong-Jy Shyu31Department of Aviation and Communication...

Báo cáo hóa học: "Research Article A Novel Approach to the Design of Oversampling Low-Delay Complex-Modulated Filter Bank Pairs" doc

... design of analysis prototype filter with minimum group delay and approximately linear-phase frequency response in the passband and the transition band and (ii) Design of synthesis prototypefilter ... groupdelay not only in the passband but also in the transitionband. The mean value of the group delay ranges below that of linear-phase filters of the same length. The observed overallsignal delay ... in the passband and the transition bands. As the objectivefunction to be minimised we adopt a particularrepresentation of the group delay [20], while the stopband magnitude specifications of the...

báo cáo hóa học:" Research Article A New Technique for the Digitization and Restoration of Deteriorated Photographic Negatives" pptx

... cost-eﬀective camera and LCD system that are already available to most libraries and museums. An initial analysis is provided to show the accuracy of this method and promising results of restoration of actual ... and analysis of a new image-based photonegative restoration system. Deteriorated acetate-based safety negatives are complex objects due to the separation and channeling of their multiple layers ... designate this information as“photometric” in the sense that the intensity variations along the emulsion layer are the crucial photometric property to becaptured. Any damage to this layer or to anything...

Báo cáo hóa học: " Research Article A Variational Approach to the Modeling of MIMO Systems" docx

... they are very useful in the study of scattering the- ory and their power comes from the fact that they arerepresentation independent; one may work either in the realspaceorintheFourierdualandcanmovefromonerepresentation ... which asso-ciates to the two vectors f∈ H∗ and g ∈ H the scalarf | g. The ket and bra notations satisfy the usual prop-erties of the Hilbert space including linearity and normal-ization; they ... show brie y how standardmethods of scattering theory can be used to study MIMOchannel. Here we exhibit rapidly the par allel between the channel equation of radio propagation and the so-calledBorn...

Báo cáo y học: " Histone deacetylases — a new target for suppression of cartilage degradation" pdf

... DNA. In the case of H3 and H4, specific lysinesidechains undergo acetylation, through the action of histoneacetyltransferases, by way of acetyl coenzyme A, a stepwhich is associated with transcriptional ... modulated by cytokines, intracellular signaling, and transcription factor action, but recent work by Young and colleagues [1] indicates that there is significantly more to this process than has ... trichostatin A and butyrate were shown to drastically reduce expression of theseenzymes relatively selectively, with concomitant inhibition of breakdown of matrix components. This family of enzymes...

Báo cáo y học: "Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units"

... the acquisition of data. NMhelped to draft the manuscript, and participated in the acquisi-tion of data. AZ participated in the coordination of the study.AAZ participated in the design of the ... purposes)Authors' contributionsKA and IK contributed equally to the work. KA and IK drafted the manuscript and participated in the acquisition of data and the study design. JB participated in the ... approximately 550 patients annually withan average age of 40 years. Surgery patients, coronarypatients, neonates and burn patients are treated in specializedunits. The study protocol was approved...

Xem thêm