... monopolar spindles (Fig. 5C).Discussion In this study, we have provided several lines of evi-dence indicating that the antiproliferative mechanism of action of curcumin involves the perturbation of microtubule ... acquisition andprocessing. MCF-7 cells were transfected with EGFP–a-tubulin plasmid, as described previously [20] and the stably transfected MCF-7 cells were maintained in the pres-ence of the ... checkpoint andinduces apoptosis in MCF-7 cellsMithu Banerjee, Parminder Singh and Dulal PandaDepartment of Biosciences & Bioengineering, Indian Institute of Technology Bombay, Mumbai, IndiaIntroductionCurcumin,...