Báo cáo y học: "Fat-Storing Multilocular Cells Expressing CCR5 Increase in the Thymus with Advancing Age: Potential Role for CCR5 Ligands on the Differentiation and Migration of Preadipocytes" pot
... the thymus with age. Hy-
pothesizing that the increased expression of chemokines and the CCR5 receptor may play a
role in adipocyte recruitment and/ or differentiation within the aging thymus, ... is enhanced in the
aging thymus. To further investigate a possible role
for CCR5 on immigration of fat-storing cells, we ex-
amined the expression of...
... against infected and
stressed epithelial cells [12]. Some populations of these
cells are known to be involved in the initiation of acute
inflammatory responses and in the persistence of chronic
inflammation ... T cells in the inflammatory infiltrates of oral
ulcers, erythema nodosum-like lesions and pathergy reac-
tions [7,8].
Increases in γ/δ T cells in...
... encoded by genes in the redefined
Aec2 region may be involved in secondary manifestations of
SjS, OX40L is the one factor that clearly stands out as a pri-
mary candidate gene underlying not only the ... accumulate within the cells due to the downregulation or
dysfunction of the lipid transporter. In addition, the functional
activities of cells whose differentia...
... enzymes, phagocytosis can trigger the release of anti-
inflammatory cytokines such as transforming growth factor-
beta whilst inhibiting the production of proinflammatory
cytokines, including ... disc cells to phagocytose and the capability
of apoptopic disc cells to stimulate phagocytosis could be
beneficial to the intervertebral disc in vivo in many ways. Death
of...
... pilot
investigation based on the hypothesis that older adults
with uncontrolled diabetes (poor glycemic control and
sustained hyperglycemia) engaged in resistance exercise
training for 16 ... observed with resistance training.
Moreover, the observed increase expression in hSGLT3
was significantly associated with improved glycemic
control and functional capacity....
... biologic action of vitamin
D extends well beyond the classic function to include effects
on immunity, muscle and vasculature, reproduction, and the
growth and differentiation of many cell types [14]. ... exert
many of its action through interaction with a specific intracel-
lular receptor. At the molecular level, 1,25-dihydroxyvitamin D3
inhibits the accumulation of...
... assignment
of progression was therefore a combination of the reader's
choice of the better image with the choice of first in time or the
combination of the worse image and the second in time;
assignment ... of repair. Adding information on features of repair only marginally influences the
discrimination between progression and repair.
b
Designatio...
... although
only one and five, respectively, were within coding
regions. Of the insertions and deletions within 10 Mb of
Isl1, none were within coding regions.
Isl1 is expressed in the middle ear
We ... protein is in red. (b) Secondary structure representation of the two proteins. The two LIM domains of
the ISL1 protein are colored yellow and orange, with the rema...
... see that the decline s of CD8+ T cells are
mainly composed of EMRA and EM subsets, which may
play important roles in direct killing of target cells. The
decrease of EMRA and EM subsets may result ... during ART.
Background
CD8+ T cells play an important role in protection against
intracellular pathogens. Eliminating CD8+ T lymphocytes
from monkeys during chronic SIV...
... correctly, can help
the surgeon to successfully treat high demanding
situations.
Consent
Written informed consent was obtained from the patient
for publication of this case report and the accompanying
images. ... copy of the written consent is available for
review by the Editor -in- Chief of this journal.
Authors’ contributions
GM performed the operation and made th...