... pathways, including MAPK
and PI3K pathways [2]. It is becoming evident that
signaling pathways induced by receptor tyrosine
kinases (RTK) may interact with GPCR pathways at a
variety of intracellular ...
as cell growth, differentiation, and metabolism. They
are stimulated by catecholamines, epinephrine and
norepinephrine (NE) and play important roles in car-
diovascular, respirator...
... anorexia nervosa
patients in a biweekly manner after initiation of
Table 1 Patient demographics
Demographic Healthy controls Anorexia nervosa patients P value
a
Patients, n 17 14 -
Age, years 30.4 ... result,
C 5a may be generated via thrombin-mediated coagula-
tion abnormalities that have been documented in anor-
exia nervosa patients [17,18]. In addition, phacocytic
cells are abl...
... Z, Jiang X, Gaubatz J, Yang F, Durante W,
Chan L, Schafer AI, Pownall HJ, Yang X, Wang H: Hyperhomo-
cysteinemia decreases circulating high-density lipoprotein
by inhibiting apolipoprotein A- I ... B12
deficiency [7,18,19]. Our results, in agreement with
Vrethem et al. [8] and Ramsaransing et al. [9], indicate that
Hcy increases may occur in MS in the absence of vitamin
B12 and folate...
... both
regulated by polyamines and regulates polyamine metabo-
lism in a feedback loop. Antizyme expression is regulated
translationally by a polyamine-stimulated ribosomal frame-
shifting [2,11,12]. In ... S., Matsufuji, T., Miyazaki, Y. , Murakami, Y. , Atkins,
J.F., Gesteland, R.F. & Hayashi, S. (1995) Autoregulatory frame-
shifting in decoding mammalian ornithine decarboxy...
... D., Francastel, C., Cimora, D.M., Reik, A. , Martin,
D.I.K. & Groudine, M. (2000) Nuclear localization and
histone acetylation: a pathway for chromatin opening and
transcriptional activation ... These authors suggest th at dynamic changes in the
acetylation patterns, initiated by the recruitment of h istone
acetyltransferase a nd deacetyltransferase to the LCR, may
affect globin ge...
... loci
may play a simultaneous role in response to pharmacother-
apy. Future research regarding the mysteries of asthma will
focus on not only phenotypic indicators but also better
understanding of potential ... one, as once
understood, we may be able to rely on a patient’s genetics
to aid in choosing the most appropriate therapy. As
clinicians attempting to stay current in the evolvi...
... suffering from mental
disorder, especially those placed as involuntary patients in a
psychiatric establishment. Strasbourg 2000.
37. Green L, Nayani T: Repatriating psychiatric patients. Psychiatr
Bull ... financial
planning; thus facilitating their inclusion in user and
information groups, and strategies aimed at improving
standards of care.
Recent changes to the Charging Regulations f...
... by Baraliakos et al., http://arthritis-research.com/content/7/3/R439
123
decrease in the hypervascularity typical of SpA and a
reduction of the synovial lining hyperplasia, indicating that
infliximab ... pathophysiological mechanisms
that for example lead to ankylosis in AS?
An interesting addition to our knowledge of TNF-α blockade
with infliximab in AS has been provided in a rec...
... by Ad-LacZ in
cartilage, as demonstrated by X-gal/hematoxylin and eosin staining
(original magnification 200×). A variety of cell types including (g) syn-
oviocytes, (h) lymphocytes, (i) macrophages, ... arrest inflammatory
synovium at an early stage of RA.
Introduction
Rheumatoid arthritis (RA) is a potentially very disabling dis-
ease that is characterized by chronic synovitis, a...
... Using a combination of microarrays, quantitative RT-PCR and a new fitting method for determining RNA decay
rates, we found a median half-life of 2.4 minutes and a median decay rate of 2.6 minutes ... 17 genes was used (Additional
file 2). In particular, we compared microarray data
derived by either Microarray Array Suite (MAS) or robust
multi-array analysis methods (as implemented...