... X-linked agammaglobulin-emia. A clinical and molecular analysis. Medicine(Baltimore) 75, 287–299.27 Plebani A, Soresina A, Rondelli R, Amato GM, AzzariC, Cardinale F, Cazzola G, Consolini ... ITK and the gain-of-function fusions ITK–SYK and BTK–SYKAlamdar Hussain1,2,*, Liang Yu1,3,*, Rani Faryal1,2, Dara K. Mohammad1, Abdalla J. Mohamed1,4 and C. I. Edvard Smith11 Clinical ... [70]. In addition, we and others have demonstrated that the activation and plasma membrane localization of the fusion constructare dependent on phosphatidylinositol 3-kinase signal-ing, and that...