... mild
diarrhea at the beginning of the treatment and a reversible
weight loss preventing further dose escalation. These
observations are reminiscent of earlier findings in healthy
rats after high dose intravenous ... administra-
tion. In a first in vivo study in healthy rats, repeated
intravenous injections of ErPC were well tolerated and
revealed an accumulation of E...
... or the treatment they received was inappropriate or inadequate. The
conclusion is that promoting suicide prevention requires the improving of training and skills of both
psychiatrists and many ... non-psychiatrists and especially GPs in recognizing and treating depression
and anxiety. A shift of focus of attention is required in primary care to detect potentially suicida...
... water
quality control and restoration programs. The State of
São Paulo is one of the most deforested areas in Latin
America, due to agriculture (mainly coffee and sugar-
cane), urbanisation and ... Zagatto E.A.G., Krug F.J., Bergamin Filho H.,
Jorgensen S.S., Reis B.F., Merging zones in flow injection
analysis. Part 2. Determination of Ca, Mg and K in plant mater-
ial by c...
...
Effect of pyrogen
induced fever on the pharmacokinetics of cefazolin in goats.
Indian J Pharmacol 1992. 24,51.
15. Saini SPS. Effect of fever on pharmacokinetics and dosage
regimen of amikacin in ... 2415-2418.
2. Ahmad AH, Bagha HS, Sharma LD. Pharmacokinetics of
gentamicin following single dose of intravenous
administration in normal and febrile goats. J Vet P...
... a relative decrease in the
number of studies aimed at gaining an understanding
of the structural conformation of chromatin, and the
changes in chromatin structure that accompany gene
activation. ... detailed
understanding of the true nature of active chromatin.
There are many levels at which gene activation is facil-
itated by increasing chromatin accessibility, whether it...
... acti-
vation of the ERK signal cascade and that miR-34a
downregulates MEK1, which is one of the main regu-
lators of ERK signaling, indicates that miR-34a is
involved in negative-feedback regulation ... the
formation of complex regulatory networks.
Model of regulatory networks in the (A)
MAPK signaling pathway, (B) Notch signal-
ing pathway, (C) EcR signaling pathway, (D)
Hipp...
... P
i
washes and incubation with
the nuclear stain 4¢,6-diamidino-2-phenylindone for 20 min,
the MSCs were washed in NaCl ⁄ P
i
for 10 min and
mounted in gelvatol for microscopic imaging.
Protein extraction ... repressed.
Hypoxia
⁄
SD induces cleavage of pro-IL-1b into
mature IL-1b
Given that hypoxia⁄ SD induced significant transla-
tional upregulation of pro-IL-1b and that process...
... test data and the full line on training data. The
straight line represents a random classification and the cross indi-
cates the cut-off value used in PREDMUT.
J. Carlsson et al. Prediction of p53 ... stability of the protein, indicating that it
either possesses more relaxed binding that tolerates
small changes in structure, or that it binds harder and
thereby stabilizes the prot...
... Pasqualucci L, Falini B & Stirpe F (1998)
Evaluation of immunotoxins containing single-chain
ribosome-inactivating proteins and an ati CD-22
monoclonal antibody (OM-124): in vitro and in vivo
studies. ... added and, after incubating the plates for 30 min at
37 °C and 30 min at 24 °C, the hemagglutination titer was
scored visually.
Hemagglutination-inhibition assays were p...