Báo cáo khoa học: "Distribution of trkA in cerebral cortex and diencephalon of the mongolian gerbil after birth" docx

... neurotrophines in the cerebral cortex and diencephalon during mongolian gerbil brainontogeny.Key words: trkA, NGF, mongolian gerbil, cerebral cortex, diencephalon Introduction In the developing ... to neurotrophinresponsiveness. To investigate the time course of NGF and trkA, we examined trkA expression in the cerebral cortex and diencephalon of postnatal Mongolian Gerbil brain. Thisstudy ... composed of trkA and p75 receptors, also known ashigh and low affinity receptors, according to their ligandbinding affinity [3,7,12]. The trkA protein, a tyrosine kinasereceptor of 140 kDa...

Tài liệu Báo cáo khoa học: Cell surface heparan sulfate proteoglycans Target and partners of the basic ®broblast growth factor in rat Sertoli cells pptx

... 509 The bFGF binding requires speci®c motifs on highlysulfated HS chains. Sodium chlorate, in inducing structuralalteration of HS chains, prevents the bFGF binding. Ourresults indicate that the ... sequences of HS chains are de®ned for the bFGF binding and for the recognition of the speci®c bFGFreceptor, leading to the formation of a ternary complexcomprising HSPG±bFGF±FGFR. These oligosaccharidicmotifs ... ngámL)1) and/ or sodium chlorate (10 mM).Before RNA extraction, cells were incubated for 24 heither in the absence or in prese nce of FSH, dbcAMP,cholera toxin or bFGF, either in combination...

Báo cáo khoa học: Polysaccharide binding sites in hyaluronate lyase – crystal structures of native phage–encoded hyaluronate lyase and its complexes with ascorbic acid and lactose docx

... for the binding because of the uniquepositions of LysC179 and GluB167 and the scope of conformational changes of their side chains (Fig. 2A).On moving further from the N-terminus and towards the ... Phe264. The structures of the complexes of HylP2 indicate the existence of three sub-sites in the long concave binding site of the enzymewhere lactose and ascorbic acid are located. The bind-ing ... concentrations in the range 0.2–8 mm [15],which are within the range of the IC50 of ascorbic acidagainst HylP2. For the ﬁrst time, the present studyprovides insight into the inhibitor binding sites in HylP2...

Báo cáo khoa học: From meiosis to postmeiotic events: Alignment and recognition of homologous chromosomes in meiosis ppt

... DSBs and the con-sequent recombination are involved in homologysearching in S. cerevisiae [5]. On the other hand,homologous pairing is independent of recombination in many organisms [5,6]. After ... formation and recombination of DNA,some residual levels of pairing still remain, suggestingthat a DSB-independent pairing mechanism may also beoperating in this organism [42–44].On the other hand, ... homologous DNAs involved in the process of homology searching and recombination along the chro-mosomes allow DSB-dependent pairing to occur [5].However, even in a mutant lacking Spo11 and other keyfactors...

Báo cáo khoa học: "INTEGRATING MULTIPLE KNOWLEDGE SOURCES FOR DETECTION AND CORRECTION OF REPAIRS IN HUMAN-COMPUTER DIALOG*" potx

... in words of the matched string, and the number of words between the two matched strings. Numbers in parentheses indicate the number of occurrences, and probabilities represent the likelihood ... (determined perceptually), and continuity of the speech im- mediately preceding and following the editing expression ("continuous" means there was no silent pause on either side of the ... edits, and also including the original string un- changed. Each of these strings was analyzed by the parser. When the original sequence did not 60 parse, but one of edits resulted in a sequence...

Báo cáo khoa học: "Wood density traits in Norway spruce understorey: effects of growth rate and birch shelterwood densit" ppsx

... progressive increase in the dimensions and corresponding changes in the form, structure and disposition of the cells " and " ;the cells in gen-eral having reached their ... tempera-ture and radiation indices and their adjustment to hor-izontal and inclined forest land, Stud. For. Suec. 194,1994.[35] Nakagawa S., Influence of pruning and lightintensity ... 50]. In frost-prone areas, the use of shelterwoods is of special interest as a means of raising the minimum temperature and reducing excesslight, thereby reducing frost...

Tài liệu Báo cáo khoa học: "Finding Synonyms Using Automatic Word Alignment and Measures of Distributional Similarity" pdf

... and for applying the frequency cutoff. In the following section we describe the data and resources used in our experiments and ﬁnally the results of this approach.869Proceedings of the COLING/ACL ... of conveying the same in- formation in different ways are referred to by the term paraphrase and in the case of single wordssharing the same meaning we speak of synonyms.Identiﬁcation of synonyms ... well-known combinatorialmeasure that computes the ratio between the size of the intersection of two feature sets and the sum of the sizes of the individual feature sets. Dice†is a measure that incorporates...

Báo cáo khoa học: Staphylococcus aureus elongation factor G – structure and analysis of a target for fusidic acid pdf

... affect the FA-binding pocket at the domain interface.Residues 666 and 670, within one b-strand of domain V, are also important for interdomain interac-tions. The N-terminal part of the strand interacts ... at the surface of EF-G and forms part of the FA-bindingsite, it points to the opposite direction in our structure,interacting with Glu93 in helix BG and Tyr126 in helixCG in the core of the ... Comparison of the positions of the tip of domain IV in all available EF-G structures in the PDB. The structures were superimposed on the basis of domains I and II. Looking from the direction of the...

Báo cáo khoa học: Relation between domain evolution, speciﬁcity, and taxonomy of the a-amylase family members containing a C-terminal starch-binding domain pot

... evolution of this domain [30].This together with the ﬁndings of the present study indicatesa separate evolution of the domains C and E compared to the domains A and B. The recent introduction ... thick dashed line separates the amylase group from the CGTase group, while the thin dotted line indicates the change of the border between the two parts in the C domain tree and the SBD tree.Ó ... N-terminal part of the enzymes toone in uenced more by taxonomy at the C-terminal part of the same enzymes (Figs 3 and 4) can be seen in the presentstudy. The four- and ﬁve-domain members of GH...

Báo cáo khoa học: "Viterbi Training for PCFGs: Hardness Results and Competitiveness of Uniform Initialization" doc

... of the string 10.A parse of the string sφusing Gφwill be usedto get an assignment by setting Yr= 0 if the ruleVYr→ 0 or V¯Yr→ 1 are used in the derivation of the parse tree, and ... self-training for parsing. In Proc. of HLT-NAACL.D. McClosky, E. Charniak, and M. Johnson. 2006b.Reranking and self-training for parser adaptation. In Proc. of COLING-ACL.R. McDonald and G. ... solving and even ap-proximating Viterbi training for PCFGs isNP-hard. We motivate the use of uniform-at-random initialization for Viterbi EM asan optimal initializer in absence of furtherinformation...

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