... birth of the field of biochemical engineer-ing. Following on the heels of the antibiotic products was the development of efficient microbial processes for the manufacture of vitamins (riboflavin,cyanocobalamine,biotin), ... the later development of bio-processes in Japan is the discovery of monosodium l-glutamate as a flavorenhancer of food in 1908. Kikunae Ikeda, Professor of the University of Tokyo,was interested ... battle.Workers at the University of Wisconsin isolated ultraviolet-induced mutants of Demerec’s strain. One of these, Wis. Q-176, which produced 550 mg/ml, is theparent of most of the strains used in...