... found in Parkin-son’s disease and other synucleinopathies. J Biol Chem278, 24095–24102.64 Ihara M, Yamasaki N, Hagivara A, Tanigaki A, Kit-ano A, Hikawa R, Tomimoto H, Noda M, TakanashiM, ... [40]. The predominance of 3R-tau results in the tauopathyobserved in Pick disease, whereas the predominance of 4R-tau causes tau pathology and neuronal loss in pro-gressive supranuclear palsy and ... et al. [53]revealed that DYRK 1A phosphorylates APP atThr668 in vitro and in mammalian cells. The increase in DYRK 1A concentration is associated with increasedAPP phosphorylation at Thr668 and...