Chapter 081 Principles of Cancer Treatment (Part 11) potx
Chapter 081. Principles of Cancer Treatment (Part 11) potx
... drugs; SIADH, syndrome of inappropriate antidiuretic hormone; WBCs, white blood cells. Chapter 081. Principles of Cancer Treatment (Part 11) Table 81-2 Commonly Used Cancer Chemotherapy ... continuous; 1250 mg/m2 bid 2 weeks on/ 1 off; 829 mg/m2 bid 2 weeks on/ 1 off + 60 mg/d leucovorin Diarrhea Hand-foot syndrome Prodrug of 5FU due to intratumoral metabolism Cytosine ... Myalgia Use limited to leukemia Altered methylation of DNA alters gene expression Gemcitabine 1000 mg/m2 IV Marrow Nausea of 6 weeks Diarrhea Neutropenia Miscellaneous Arsenic...
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Chapter 081. Principles of Cancer Treatment (Part 21) potx
... administration of chemotherapy. Also, patients with myeloid leukemias undergoing induction therapy may have a slight reduction in the duration of neutropenia if G-CSF is Chapter 081. Principles of Cancer ... extensive compromise of marrow by prior radiation or chemotherapy; or active, open wounds or deep-seated infection—may support primary treatment with G-CSF or GM-CSF. Administration of G-CSF or GM-CSF ... concomitant chemoradiation treatment, particularly those with thoracic neoplasms, likewise are not generally recommended for treatment. In contrast, administration of G-CSF to high-risk patients...
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Chapter 081. Principles of Cancer Treatment (Part 22) potx
... dolasetron (Anzamet), 100 mg IV or p.o.; Chapter 081. Principles of Cancer Treatment (Part 22) Nausea and Vomiting The most common side effect of chemotherapy administration is nausea, ... classes of agent is the cornerstone of successful management of chemotherapy-induced nausea and vomiting. Of great importance are the prophylactic administration of agents and such psychological ... cycles of chemotherapy. Accordingly, antiemesis agents differ in their locus and timing of action. Combining agents from different classes or the sequential use of different classes of agent...
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Chapter 081. Principles of Cancer Treatment (Part 1) docx
... benefit. One of the challenges of cancer treatment is to use the various treatment modalities alone and together in a fashion that maximizes the chances for patient benefit. Cancer treatments ... attention to minimizing the toxicity of potentially toxic treatments becomes a significant goal. Irrespective of the clinical scenario, the guiding principle of cancer treatment should be primum succerrere, ... this "organ-like" behavior of tumors may provide additional clues to cancer control and treatment. treatment has the potential to cause harm, and treatment may be given that produces...
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Chapter 081. Principles of Cancer Treatment (Part 2) ppsx
... those with pancolonic involvement with ulcerative colitis), the presence of Chapter 081. Principles of Cancer Treatment (Part 2) Figure 81-1 ... Principles of Cancer Surgery Surgery is used in cancer prevention, diagnosis, staging, treatment (for both localized and metastatic disease), palliation, and rehabilitation. Prophylaxis Cancer ... incisional biopsy is the procedure of second choice. A wedge of tissue is removed, and an effort is made to include the majority of the cross-sectional diameter of the tumor in the biopsy to minimize...
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Chapter 081. Principles of Cancer Treatment (Part 3) pps
... information for treatment planning and may determine the extent and nature of primary cancer treatment. Treatment Surgery is the most effective means of treating cancer. Today about 40% of cancer ... resection of certain tumors that would otherwise not be possible. Chapter 081. Principles of Cancer Treatment (Part 3) Staging As noted in Chap. 77, an important component of patient ... including local control of tumor, preservation of organ function, debulking that permits subsequent therapy to work better, and staging information on extent of involvement. Cancer surgery aiming...
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Chapter 081. Principles of Cancer Treatment (Part 4) pdf
... Chapter 081. Principles of Cancer Treatment (Part 4) Palliation Surgery is employed in a number of ways for supportive care: insertion of central venous catheters, control of pleural ... for recurrent pulmonary emboli, stabilization of cancer- weakened weight-bearing bones, and control of hemorrhage, among others. Surgical bypass of gastrointestinal, urinary tract, or biliary ... (Fig. 81-2). Plotting the fraction of surviving cells against doses of x-rays or gamma radiation, the curve has a shoulder that reflects the cell's repair of sublethal damage, followed by...
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Chapter 081. Principles of Cancer Treatment (Part 5) ppt
... the target volume is often the cause of complications to tissues in the transit volume, and the minimum dose in the target Chapter 081. Principles of Cancer Treatment (Part 5) Although ... include the D0 of the tumor (the dose required to deliver an average of one lethal hit to all the cells in a population), the Dq of the tumor (the threshold dose—a measure of the cell's ... basis of the amount of radiation absorbed in the patient; it is not based on the amount of radiation generated by the machine. The rad (radiation absorbed dose) is defined as 100 erg of energy...
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Chapter 081. Principles of Cancer Treatment (Part 6) ppsx
... dose of therapeutic radiation exists below which the incidence of second cancers is decreased. High rates of second tumors occur in people who receive as little as 1000 cGy. Chapter 081. Principles ... breast cancer, Hodgkin's disease, head and neck cancer, prostate cancer, and gynecologic cancers. Radiation therapy can also palliate disease symptoms in a variety of settings: relief of bone ... Principles of Cancer Treatment (Part 6) Application to Patients Teletherapy Radiation therapy can be used alone or together with chemotherapy to produce cure of localized tumors and control of...
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Chapter 081. Principles of Cancer Treatment (Part 7) docx
... described in Chapter 80, successful tumors have activated biochemical pathways that lead to uncontrolled proliferation through the Chapter 081. Principles of Cancer Treatment (Part 7) Karnofsky ... providing a basis for patients to make sensible choices. Cancer Drugs: Overview and Principles for Use Cancer drug treatments are of four broad types. Conventional chemotherapy agents were ... connotes disappearance of all tumor; progression of disease signifies an increase in size of existing lesions by >25% from baseline or best response or development of new lesions; and "stable"...
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