...
Chapter 057. Photosensitivity and
Other Reactions to Light
(Part 5)
Polymorphous Light Eruption
After sunburn, the most common type of photosensitivity disease is
polymorphous light eruption ... exposure.
Phototoxicity and Photoallergy
These photosensitivity disorders are related to the topical or systemic
administration of drugs and other chemical...
... penetrates to the dermis and is capable of altering
structural and matrix proteins that contribute to photoaging of chronically sun-
exposed skin, particularly in individuals of light complexion. ... between 290 and
Photosensitivity occurs when a photon-absorbing chemical (chromophore)
present in the skin absorbs incident energy, becomes excited, and transfers the
absorbed...
... extent in the
Chapter 057. Photosensitivity and
Other Reactions to Light
(Part 2)
Molecular Targets for UVR-Induced Skin Effects
Epidermal DNA, predominantly in keratinocytes and in Langerhans ... released into the circulation from the bone marrow
and the liver and are transported to the skin, where they absorb incident energy
both in the Soret band, around 400...
... persistent photosensitivity is known as chronic
actinic dermatitis. These patients are typically elderly men with a long history of
Chapter 057. Photosensitivity and
Other Reactions to Light
(Part ... energy, become photoexcited,
generate ROS, and evoke cutaneous photosensitivity. The mechanism of porphyrin
photosensitization is known to be photodynamic, or oxygen...
...
Fig. 57-1.
Figure 57-1
Chapter 057. Photosensitivity and
Other Reactions to Light
(Part 7)
Porphyria cutanea tarda is the most common type of human porphyria and
is associated with decreased ... include an acute photosensitivity
characterized by subjective burning and stinging of exposed skin that often
An algorithm for the diagnosis of a patient with photo...
... dioxide 25
Chapter 057. Photosensitivity and
Other Reactions to Light
(Part 8)
Natural photoprotection is provided by structural proteins in the epidermis,
particularly keratins and melanin. ... effects of long-term UV-B phototherapy
and PUVA photochemotherapy mimic those seen in individuals with chronic sun
exposure and include skin dryness, actinic keratoses,...
... including the face, the neck, and the hands. Major
risk factors include male sex, childhood sun exposures, older age, fair skin, and
residence at latitudes closer to the equator. Whites of darker complexions ... but this is likely due to failure to control for confounding
factors such as sunscreen stability and frequency of application. Since no
prospective studies are availab...
... difficulty interpreting and reacting to environmental sounds
since primary auditory cortex and subcortical auditory relays are intact. Since
auditory information cannot be conveyed to the language ... paranoid reactions are frequent in the acute stages. Cerebrovascular
lesions are the most frequent cause.
Chapter 027. Aphasia, Memory Loss, and
Other Focal Cerebral Disorde...
... Chapter 027. Aphasia, Memory Loss, and
Other Focal Cerebral Disorders
(Part 11)
The Occipitotemporal Network for Face and Object Recognition:
Prosopagnosia and Object Agnosia ... association areas of occipitotemporal cortex and then to other heteromodal
and paralimbic areas of the cerebral cortex. Bilateral lesions in the fusiform and
lingual gyri of the occipitot...
...
Smokeless tobacco is the fastest growing part of the tobacco industry and
represents a substantial health risk. Chewing tobacco is a carcinogen linked to
Chapter 078. Prevention and Early
Detection ... prevention
and early detection (also known as cancer control) to expand beyond the
identification and avoidance of carcinogens. Specific interventions to prevent
cancer in...