... copeptin, a novel biomarker, in lower respiratory tract infections. Eur J Clin Invest 2007, 37:145-152.22. Christ-Crain M, Muller B: Biomarkers in respiratory tract infections: diagnostic guides ... management and superior allocation of health care resources. Trial Registration : NCT00350987.IntroductionThe assessment of disease severity and prediction of out-come in lower respiratory tract infections ... contributionsPS, BM and MCC had the idea and initiated the study. MCC, WZ, HCB, MW, PS,US, and BM designed the study and wrote the protocol. PS, US, KR, RT, CF, IW,SN, CB, TF, RS, CH, TB, CH, MK, WZ and BM...